Deep learning has generated diverse perspectives in astronomy, with ongoing discussions between proponents and skeptics motivating this review. We examine how neural networks complement classical statistics, extending our data analytical toolkit for modern surveys. Astronomy offers unique opportunities through encoding physical symmetries, conservation laws, and differential equations directly into architectures, creating models that generalize beyond training data. Yet challenges persist as unlabeled observations number in billions while confirmed examples with known properties remain scarce and expensive. This review demonstrates how deep learning incorporates domain knowledge through architectural design, with built-in assumptions guiding models toward physically meaningful solutions. We evaluate where these methods offer genuine advances versus claims requiring careful scrutiny. - Neural architectures overcome trade-offs between scalability, expressivity, and data efficiency by encoding physical symmetries and conservation laws into network structure, enabling learning from limited labeled data. - Simulation-based inference and anomaly detection extract information from complex, non-Gaussian distributions where analytical likelihoods fail, enabling field-level cosmological analysis and systematic discovery of rare phenomena. - Multi-scale neural modeling bridges resolution gaps in astronomical simulations, learning effective subgrid physics from expensive high-fidelity runs to enhance large-volume calculations where direct computation remains prohibitive. - Emerging paradigms-reinforcement learning for telescope operations, foundation models learning from minimal examples, and large language model agents for research automation-show promise though are still developing in astronomical applications.
Ajit Kumar Mehta, Digvijay Wadekar, Isha Anantpurkar
et al.
We present the population properties of binary black hole mergers identified by the $\tt{IAS\text{-}HM}$ pipeline (which incorporates higher-order modes in the search templates) during the third observing run (O3) of the LIGO, Virgo, and KAGRA (LVK) detectors. In our population inference analysis, instead of only using events above a sharp cut based on a particular detection threshold (e.g., false alarm rate), we use a Bayesian framework to consistently include both marginal and confident events. We find that our inference based solely on highly significant events ($p_{\mathrm{astro}} \sim 1$) is broadly consistent with the GWTC-3 population analysis performed by the LVK collaboration. However, incorporating marginal events into the analysis leads to a preference for stronger redshift evolution in the merger rate and an increased density of asymmetric mass-ratio mergers relative to the GWTC-3 analysis, while remaining within its allowed parameter ranges. Using simple parametric models to describe the binary black hole population, we estimate a merger rate density of $32.4^{+18.5}_{-12.2}\ \mathrm{Gpc}^{-3}\,\mathrm{yr}^{-1}$ at redshift $z = 0.2$, and a redshift evolution parameter of $κ= 4.4^{+1.9}_{-2.0}$. Assuming a power-law form for the mass ratio distribution ($\propto q^β$), we infer $β= 0.1^{+1.9}_{-1.4}$, indicating a relatively flat distribution. These results highlight the potential impact of marginal events on population inferences and motivate future analyses with data from upcoming observing runs.
The LIGO Scientific Collaboration, the Virgo Collaboration, the KAGRA Collaboration
et al.
Version 4.0 of the Gravitational-Wave Transient Catalog (GWTC-4.0) adds new candidates detected by the LIGO, Virgo, and KAGRA observatories through the first part of the fourth observing run (O4a: 2023 May 24 15:00:00 to 2024 January 16 16:00:00 UTC) and a preceding engineering run. In this new data, we find 128 new compact binary coalescence candidates that are identified by at least one of our search algorithms with a probability of astrophysical origin $p_{\rm astro} \geq 0.5$ and that are not vetoed during event validation. We also provide detailed source property measurements for 86 of these that have a false alarm rate $< 1 \rm{yr}^{-1}$. Based on the inferred component masses, these new candidates are consistent with signals from binary black holes and neutron star-black hole binaries (GW230518_125908 and GW230529_181500). Median inferred component masses of binary black holes in the catalog now range from $5.79\,M_\odot$ (GW230627_015337) to $137\,M_\odot$ (GW231123_135430), while GW231123_135430 was probably produced by the most massive binary observed in the catalog. For the first time we have discovered binary black hole signals with network signal-to-noise ratio exceeding 30, GW230814_230901 and GW231226_01520, enabling high-fidelity studies of the waveforms and astrophysical properties of these systems. Combined with the 90 candidates included in GWTC-3.0, the catalog now contains 218 candidates with $p_{\rm astro} \geq 0.5$ and not otherwise vetoed, doubling the size of the catalog and further opening our view of the gravitational-wave Universe.
PURPOSE The aim of this guideline is to present recommendations regarding moderately hypofractionated (240-340 cGy per fraction) and ultrahypofractionated (500 cGy or more per fraction) radiation therapy for localized prostate cancer. METHODS AND MATERIALS The American Society for Radiation Oncology convened a task force to address 8 key questions on appropriate indications and dose-fractionation for moderately and ultrahypofractionated radiation therapy, as well as technical issues, including normal tissue dose constraints, treatment volumes, and use of image guided and intensity modulated radiation therapy. Recommendations were based on a systematic literature review and created using a predefined consensus-building methodology and Society-approved tools for grading evidence quality and recommendation strength. RESULTS Based on high-quality evidence, strong consensus was reached for offering moderate hypofractionation across risk groups to patients choosing external beam radiation therapy. The task force conditionally recommends ultrahypofractionated radiation may be offered for low- and intermediate-risk prostate cancer but strongly encourages treatment of intermediate-risk patients on a clinical trial or multi-institutional registry. For high-risk patients, the task force conditionally recommends against routine use of ultrahypofractionated external beam radiation therapy. With any hypofractionated approach, the task force strongly recommends image guided radiation therapy and avoidance of nonmodulated 3-dimensional conformal techniques. CONCLUSIONS Hypofractionated radiation therapy provides important potential advantages in cost and convenience for patients, and these recommendations are intended to provide guidance on moderate hypofractionation and ultrahypofractionation for localized prostate cancer. The limits in the current evidentiary base-especially for ultrahypofractionation-highlight the imperative to support large-scale randomized clinical trials and underscore the importance of shared decision making between clinicians and patients.
PURPOSE The aim of this guideline is to present recommendations regarding moderately hypofractionated (240-340 cGy per fraction) and ultrahypofractionated (500 cGy or more per fraction) radiation therapy for localized prostate cancer. METHODS AND MATERIALS The American Society for Radiation Oncology convened a task force to address 8 key questions on appropriate indications and dose-fractionation for moderately and ultrahypofractionated radiation therapy, as well as technical issues, including normal tissue dose constraints, treatment volumes, and use of image guided and intensity modulated radiation therapy. Recommendations were based on a systematic literature review and created using a predefined consensus-building methodology and Society-approved tools for grading evidence quality and recommendation strength. RESULTS Based on high-quality evidence, strong consensus was reached for offering moderate hypofractionation across risk groups to patients choosing external beam radiation therapy. The task force conditionally recommends ultrahypofractionated radiation may be offered for low- and intermediate-risk prostate cancer but strongly encourages treatment of intermediate-risk patients on a clinical trial or multi-institutional registry. For high-risk patients, the task force conditionally recommends against routine use of ultrahypofractionated external beam radiation therapy. With any hypofractionated approach, the task force strongly recommends image guided radiation therapy and avoidance of nonmodulated 3-dimensional conformal techniques. CONCLUSIONS Hypofractionated radiation therapy provides important potential advantages in cost and convenience for patients, and these recommendations are intended to provide guidance on moderate hypofractionation and ultrahypofractionation for localized prostate cancer. The limits in the current evidentiary base-especially for ultrahypofractionation-highlight the imperative to support large-scale randomized clinical trials and underscore the importance of shared decision making between clinicians and patients.
Purpose The AstroBio Cube Satellite (ABCS) will deploy within the inner Van Allen belt on the Vega C Maiden Flight launch opportunity of the European Space Agency. At this altitude, ABCS will experience radiation doses orders of magnitude greater than in low earth orbit, where CubeSats usually operate. The paper aims to estimate the irradiation effect on the ABCS payload in the orbital condition, their possible mitigation designing shielding solutions and performs a preliminary representativity simulation study on the ABCS irradiation with fission neutron at the TAPIRO (TAratura Pila Rapida Potenza 0) nuclear research reactor facility at ENEA. Methods We quantify the contributions of geomagnetically trapped particles (electron and proton), Galactic Cosmic Rays (GCR ions), Solar energetic particle within the ABCS orbit using the ESA’s SPace ENVironment information system. FLUKA (Fluktuierende Kaskade—Fluctuating Cascade) code models the ABCS interaction with the orbital source. Results We found a shielding solution of the weight of 300 g constituted by subsequent layers of tungsten, resins, and aluminium that decreases on average the 20% overall dose rate relative to the shielding offered by the only satellite’s structure. Finally, simulations of neutron irradiation of the whole ABCS structure within the TAPIRO’s thermal column cavity show that a relatively short irradiation time is requested to reach the same level of 1 MeV neutron Silicon equivalent damage of the orbital source. Conclusions The finding deserves the planning of a future experimental approach to confirm the TAPIRO’s performance and establish an irradiation protocol for testing aerospatial electronic components.
The LIGO, Virgo, and KAGRA (LVK) collaboration has announced 90 coalescing binary black holes (BBHs) with $p_{\rm astro} > 50\%$ to date, however, the origin of their formation channels is still an open scientific question. Given various properties of BBHs (BH component masses and individual spins) inferred using the default priors by the LVK, independent groups have been trying to explain the formation of the BBHs with different formation channels. Of all formation scenarios, the chemically homogeneous evolution (CHE) channel has stood out with distinguishing features, namely, nearly-equal component masses and preferentially high individual spins aligned with the orbital angular momentum. We perform Bayesian inference on the BBH events officially reported in GWTC-3 with astrophysically-predicted priors representing different formation channels of the isolated binary evolution (CEE: common-envelope evolution channel; CHE; SMT: stable mass transfer). Given assumed models, we report strong evidence for GW190517\_055101 being most likely to have formed through the CHE channel. Assuming the BBH events in the subsample are all formed through one of the isolated binary evolution channels, we obtain the lower limits on the local merger rate density of these channels at $11.45 ~\mathrm{Gpc^{-3}~yr^{-1}}$ (CEE), $0.18 ~\mathrm{Gpc^{-3}~yr^{-1}}$ (CHE), and $0.63 ~\mathrm{Gpc^{-3}~yr^{-1}}$ (SMT) at $90\%$ credible level.
PURPOSE This practice parameter aims to detail the processes, qualifications of personnel, patient selection, equipment, patient and personnel safety, documentation, and quality control and improvement necessary for an HDR brachytherapy program. METHODS AND MATERIALS This practice parameter was revised collaboratively by the American College of Radiology (ACR), the American Brachytherapy Society (ABS), and the American Society for Radiation Oncology (ASTRO). RESULTS Brachytherapy is a radiotherapeutic modality in which radionuclide or electronic sources are used to deliver a radiation dose at a distance of up to a few centimeters by surface, intracavitary, intraluminal, or interstitial application. Brachytherapy alone or combined with external beam radiotherapy plays an important role in the management and treatment of patients with cancer. High-dose-rate (HDR) brachytherapy uses radionuclides, such as iridium-192, at dose rates of ≥12 Gy/hr to a designated target point or volume, and it is an important treatment for a variety of malignant and benign conditions. Its use allows for application of high doses of radiation to defined target volumes with relative sparing of adjacent critical structures. CONCLUSIONS HDR brachytherapy requires detailed attention to personnel, equipment, patient and personnel safety, and continuing staff education. Coordination between the radiation oncologist and treatment planning staff and effective quality assurance procedures are important components of successful HDR brachytherapy programs.
Fundamental properties of neutrinos are investigated by studying double beta decays ( β β -decays), while atro-neutrino nucleo-syntheses and astro-neutrino productions are investigated by studying inverse beta decays (inverse β-decays) induced by astro-neutrinos. Neutrino nuclear responses for these β β and β-decays are crucial for these neutrino studies in nuclei. This reports briefly perspectives on experimental studies of neutrino nuclear responses (square of nuclear matrix element) for β β -decays and astro-neutrinos by using nuclear and leptonic (muon) charge-exchange reactions
Esse artigo discute a questão temporal em cosmologia, em particular a crítica de Gödel ao uso de um tempo cósmico global. Examina também os sistemas de coordenadas que permitem a separação da variedade espaço-tempo em três dimensões de espaço e um tempo único comum. Descreve a possibilidade de usar um sistema gaussiano que permite tal separação, e examina ainda as condições em que um tempo cósmico não pode ser usado para cobrir toda a variedade, como no modelo de Gödel.
M. L. Lister, D. C. Homan, K. I. Kellermann
et al.
We have analyzed the parsec-scale jet kinematics of 447 bright radio-loud AGN, based on 15 GHz VLBA data obtained between 1994 August 31 and 2019 August 4. We present new total intensity and linear polarization maps obtained between 2017 January 1 to 2019 August 4 for 143 of these AGN. We tracked 1923 bright features for five or more epochs in 419 jets. A majority (60%) of the well-sampled jet features show either accelerated or non-radial motion. In 47 jets there is at least one non-accelerating feature with an unusually slow apparent speed. Most of the jets show variations of 10 to 50 deg in their inner jet position angle (PA) over time, although the overall distribution has a continuous tail out to 200 deg. AGN with SEDs peaked at lower frequencies tend to have more variable PAs, with BL Lacs being less variable than quasars. The Fermi LAT gamma-ray associated AGN also tend to have more variable PAs than the non-LAT AGN in our sample. We attribute these trends to smaller viewing angles for the lower spectral peaked and LAT-associated jets. We identified 13 AGN where multiple features emerge over decade-long periods at systematically increasing or decreasing PAs. Since the ejected features do not fill the entire jet cross-section, this behavior is indicative of a precessing flow instability near the jet base. Although some jets show indications of oscillatory PA evolution, we claim no bona fide cases of periodicity since the fitted periods are comparable to the total VLBA time coverage.
ABSTRACT Tourism is regarded as a key sector through which to bring about sustainable development in rural areas. A suitable product offering should be identified that matches the rural area’s unique resources with market demand. The Karoo Rural Node in South Africa’s unique landscape coupled with hosting astronomy sites of global importance presents the ideal opportunity to develop Astro Tourism as niche offering. This paper explores the region’s state of readiness to harness this potential through describing existing visitors’ travel behaviour, experiences and expectations, alongside views from supply side stakeholders. Mixed methodology presents evaluations at the hand of an Importance Performance and a SOAR Analysis depicting the state of readiness. The paper describes how a unique experience such as Astro Tourism can be regarded as viable mechanism to bring about sustainable development in a rural context.
PURPOSE The comprehensive identification and delineation of organs at risk (OARs) are vital to the quality of radiation therapy treatment planning and the safety of treatment delivery. This guidance aims to improve the consistency of ontouring OARs in external beam radiation therapy treatment planning by providing a single standardized resource for information regarding specific OARs to be contoured for each disease site. The guidance is organized in table format as a quality assurance tool for practices and a training resource for residents and other radiation oncology students (see supplementary materials). METHODS AND MATERIALS The Task Force formulated recommendations based on clinical practice and consensus. The draft manuscript was peer reviewed by 16 reviewers, the American Society for Radiation Oncology (ASTRO) legal counsel, and ASTRO's Multidisciplinary Quality Assurance Subcommittee and revised accordingly. The recommendations were posted on the ASTRO website for public comment in June 2018 for a 6-week period. The final document was approved by the ASTRO Board of Directors in August 2018. RESULTS Standardization improves patient safety, efficiency, and accuracy in radiation oncology treatment. This consensus guidance represents an ASTRO quality initiative to provide recommendations for the standardization of normal tissue contouring that is performed during external beam treatment planning for each anatomic treatment site. Table 1 defines 2 sets of structures for anatomic sites: Those that are recommended in all adult definitive cases and may assist with organ selection for palliative cases, and those that should be considered on a case-by-case basis depending on the specific clinical scenario. Table 2 outlines some of the resources available to define the parameters of general OAR tissue delineation. CONCLUSIONS Using this paper in conjunction with resources that define tissue parameters and published dose constraints will enable practices to develop a consistent approach to normal tissue evaluation and dose documentation.
D. Thomson, David A. Palma, M. Guckenberger
et al.
Purpose Because of the unprecedented disruption of health care services caused by the COVID-19 pandemic, the American Society of Radiation Oncology (ASTRO) and the European Society for Radiotherapy and Oncology (ESTRO) identified an urgent need to issue practice recommendations for radiation oncologists treating head and neck cancer (HNC) in a time of limited resources and heightened risk for patients and staff. Methods and Materials A panel of international experts from ASTRO, ESTRO, and select Asia-Pacific countries completed a modified rapid Delphi process. Topics and questions were presented to the group, and subsequent questions were developed from iterative feedback. Each survey was open online for 24 hours, and successive rounds started within 24 hours of the previous round. The chosen cutoffs for strong agreement (≥80%) and agreement (≥66%) were extrapolated from the RAND methodology. Two pandemic scenarios, early (risk mitigation) and late (severely reduced radiation therapy resources), were evaluated. The panel developed treatment recommendations for 5 HNC cases. Results In total, 29 of 31 of those invited (94%) accepted, and after a replacement 30 of 30 completed all 3 surveys (100% response rate). There was agreement or strong agreement across a number of practice areas, including treatment prioritization, whether to delay initiation or interrupt radiation therapy for intercurrent SARS-CoV-2 infection, approaches to treatment (radiation dose-fractionation schedules and use of chemotherapy in each pandemic scenario), management of surgical cases in event of operating room closures, and recommended adjustments to outpatient clinic appointments and supportive care. Conclusions This urgent practice recommendation was issued in the knowledge of the very difficult circumstances in which our patients find themselves at present, navigating strained health care systems functioning with limited resources and at heightened risk to their health during the COVID-19 pandemic. The aim of this consensus statement is to ensure high-quality HNC treatments continue, to save lives and for symptomatic benefit.