The composition of the gut microbiota throughout life, with an emphasis on early life
J. M. Rodríguez, Kiera Murphy, C. Stanton
et al.
Abstract The intestinal microbiota has become a relevant aspect of human health. Microbial colonization runs in parallel with immune system maturation and plays a role in intestinal physiology and regulation. Increasing evidence on early microbial contact suggest that human intestinal microbiota is seeded before birth. Maternal microbiota forms the first microbial inoculum, and from birth, the microbial diversity increases and converges toward an adult-like microbiota by the end of the first 3–5 years of life. Perinatal factors such as mode of delivery, diet, genetics, and intestinal mucin glycosylation all contribute to influence microbial colonization. Once established, the composition of the gut microbiota is relatively stable throughout adult life, but can be altered as a result of bacterial infections, antibiotic treatment, lifestyle, surgical, and a long-term change in diet. Shifts in this complex microbial system have been reported to increase the risk of disease. Therefore, an adequate establishment of microbiota and its maintenance throughout life would reduce the risk of disease in early and late life. This review discusses recent studies on the early colonization and factors influencing this process which impact on health.
1233 sitasi
en
Biology, Medicine
Horizontal gene transfer: building the web of life
Shannon M. Soucy, Jinling Huang, J. Gogarten
1205 sitasi
en
Medicine, Biology
Cycle-life model for graphite-LiFePO 4 cells
John Wang, Ping Liu, Jocelyn Hicks-Garner
et al.
Mitochondrial fusion and fission in cell life and death
B. Westermann
1908 sitasi
en
Biology, Medicine
The heat shock response: life on the verge of death.
K. Richter, M. Haslbeck, J. Buchner
1889 sitasi
en
Biology, Medicine
The social life of small urban spaces
W. Whyte
Corporate Cultures: The Rites and Rituals of Corporate Life
William I. Gorden
2174 sitasi
en
Sociology, Business
Acquisition and Allocation of Resources: Their Influence on Variation in Life History Tactics
A. J. van Noordwijk, G. D. de Jong
Attempts to demonstrate trade-offs between alternative life history tactics have been relatively successful at higher taxonomic levels, but often fail at the level of individuals within a population. In this note we propose a simple model that explains this failure. The aim of our model is to understand the observations of positive correlations between life history traits where trade-offs, and hence negative correlations, are expected. It is assumed that the amount of resources that individuals can spend on life history traits varies between individuals. When some individuals spend much on several life history traits and others spend little, positive correlations are observed. Whether the observed correlations between life history traits are negative or positive depends on the relative variation in the acquisition and the variation in the allocation of resources.
The mitochondrial death/life regulator in apoptosis and necrosis.
G. Kroemer, B. Dallaporta, M. Resche-Rigon
2118 sitasi
en
Biology, Medicine
Calcium - a life and death signal
M. Berridge, M. Bootman, P. Lipp
2145 sitasi
en
Biology, Medicine
Wonderful Life: The Burgess Shale and the Nature of History
S. Gould
Diathesis-stress theories in the context of life stress research: implications for the depressive disorders.
S. Monroe, A. Simons
2044 sitasi
en
Psychology, Medicine
A life-span theory of control.
J. Heckhausen, R. Schulz
1782 sitasi
en
Psychology, Medicine
Psychometric Properties of the Life Events Checklist
Matt J. Gray, B. Litz, Julie L Hsu
et al.
1781 sitasi
en
Psychology, Medicine
Behavioral manifestations of autism in the first year of life
L. Zwaigenbaum, S. Bryson, Tracey Rogers
et al.
1634 sitasi
en
Medicine, Psychology
The Quality of American Life: Perceptions, Evaluations, and Satisfactions
A. Campbell, P. Converse, W. Rodgers
2438 sitasi
en
Medicine, Sociology
Laboratory Life
R. Krohn
vailing political tone. Significantly, there is no theory of politics to account for these patterns, and the shifting trends do not leave us with much grounds for clear long-term extrapolation. It does look, though, as if a pretty serious ideological confrontation could be building up. On the prospects of sociological theory being able to predict the future, at any rate, I see no reason to be pessimistic. What we need is at least a few sociologists to pull back from the polemics and the purely descriptive data-gathering,andmakeasustained effort to build theory around relevant topics. I think it can and will be done, although this is not the place to explain why. Finally, I have to mention the chapter by Andrew Greeley on American Catholicism. This chapter is an exception to most of what I was just saying. It says nothing, really, aboutthefuture,andthereisnotheory in it either. Greeley’s is principally a topical account of recent events in the papacy and in church politics, and the reaction of American Catholics to them. But it is as lively and informed an account of these matters as I have seen, a wonderful combination of insider’s political info with sophisticated techniques of data analysis. It is a fascinating piece of writing, and Greeley’s virulent involvement in all this adds to its steam. Some of the personal footnotes are almost worth the price of the book.
How to treat uncertainties in life cycle assessment studies?
E. Igos, E. Benetto, Rodolphe Meyer
et al.
341 sitasi
en
Engineering
The life course cube: A tool for studying lives.
L. Bernardi, J. Huinink, R. Settersten
This paper proposes a conceptualization of the life course as a set of behavioral processes characterized by interdependencies that cross time, life domains, and levels of analysis. We first discuss the need for a systematized approach to life course theory that integrates parallel and partially redundant concepts developed in a variety of disciplines. We then introduce the 'life course cube,' which graphically defines and illustrates time-domain-level interdependencies and their multiple interactions that are central to understanding life courses. Finally, in an appendix, we offer a formal account of these interactions in a language that can be readily adopted across disciplines. Our aim is to provide a consistent and parsimonious foundation to further develop life course theories and methods and integrate life course scholarship across disciplines.
314 sitasi
en
Medicine, Computer Science
How's Life? 2020
Note: ❶=top-performing OECD tier (equivalent), ❷=middle-performing OECD tier (equivalent), ❸=bottom-performing OECD tier (equivalent). ➚ indicates consistent improvement; ↔ indicates no clear or consistent trend; ➘ indicates consistent deterioration, and “...” indicates insufficient time series to determine trends since 2010. For methodological details, see the Reader’s Guide of How’s Life? 2020. Income and Wealth Household income ... ... Household wealth ... ... S80/S20 income ratio (household income for the top 20% is 7.1x that of the bottom 20%) ...