We apply Nancy Cartwright's distinction between theories and basic models to explore the history of rival approaches to modeling a notion of chance for an ideal uniform physical process known as a fair spinner. This process admits both Archimedean and non-Archimedean models. Advocates of Archimedean models maintain that the fair spinner should satisfy hypotheses such as invariance with respect to rotations by an arbitrary real angle, and assume that the optimal mathematical tool in this context is the Lebesgue measure. Others argue that invariance with respect to all real rotations does not constitute an essential feature of the underlying physical process, and could be relaxed in favor of regularity. We show that, working in ZFC, no subset of the commonly assumed hypotheses determines a unique model, suggesting that physically based intuitions alone are insufficient to pin down a unique mathematical model. We provide a rebuttal of recent criticisms of non-Archimedean models by Parker and Pruss.
This oral history interview provides Yakir Aharonov's perspective on the theoretical discovery of the Aharonov-Bohm effect in 1959, during his PhD studies in Bristol with David Bohm, the reception of the effect, the efforts to test it empirically (up to Tonomura's experiment), and some of the debates regarding the existence of the effect and its interpretation. The interview also discusses related later developments until the 1980s, including modular momentum and Berry's phase. It includes recollections from meetings with Werner Heisenberg, Richard Feynman, and Chen-Ning Yang, also mentioning John Bell, Robert Chambers, Werner Ehrenberg, Sir Charles Frank, Wendell Furry, Gunnar Källén, Maurice Pryce, Nathan Rosen, John Wheeler, and Eugene Wigner.
Alexia Steelandt, Ambre Hittinger, Lukshe Kanagaratnam
et al.
Abstract Background Uncontrolled gout can cause articular impairment but is also associated with a global and cardiovascular excess mortality, especially in dialysis population. Data documented within existing research is not conclusive regarding gout flares evolution during hemodialysis and their control by urate lowering therapy (ULT). Without clear guidelines concerning hemodialysis patients management with chronic gout, this study proposes to investigate whether gout flare incidence reduction could be observed on this population treated by urate lowering therapy versus patients without treatment. Methods We performed a retrospective cohort study in two hemodialysis centers in France. Were selected patients over 18 years old with a gout history who started hemodialysis between January 2005 and September 2015. Demographics and clinicals data were recorded at hemodialysis start and throughout 5 years of follow up. Gout flare was defined as presence of uric acid crystal in joint punction or clinically diagnosed as such with a colchicine prescription. All statistical analysis were performed in SAS® version 9.4 (SAS Institute Inc., Cary, NC). Results One hundred eighty-one patients have been included, mean age at dialysis initiation was 68.6 years (± 12.4) with 72% of men, 54% were treated by ULT: 89.7% by allopurinol and 9.3% by febuxostat. One patient received both treatments successively. After hemodialysis initiation, 35.36% patients had experienced at least one gout flare. The appearance of at least one gout flare concerned 50% of patients in no ULT group and 22.68% patients in ULT group (p = 0.0002). Dialysis efficiency was measured at regular interval during follow-up and was similar in both groups. To study the association strength between clinical factors and gout flares occurrences, a Cox model was performed; ULT is a protector factor of gout flare (HR:0,42, CI 95: 0,25-0,71). The proportion of serum urate values within the target (median 53% vs 29.3%, p < 0.0001) was significantly higher in ULT group versus no ULT group (median 53% vs 29.3%, p < 0.0001). Conclusion Urate lowering therapy limit new gout flares occurrence in hemodialysis patients with gout historyCollaboration between rheumatologists and nephrologists may help to update guidelines for urate-lowering therapies in patients on dialysis.
Knowledge of the old German masters, the so-called "Primitives", from the end of the 18th century to the middle of the 20th century, is the result of an immense collective effort, to which art historians, museum curators, critics and writers have all contributed. France has played a fundamental role in it, and deserves a synthesis that has never really been done. Whether we describe it as a matter of fortune or reception, or whether we want to look for transerts, this French vision of the German Primitives is profoundly determined by the shared political history of the two nations, made up of as many moments of openness as of prejudices into which nationalist postures enter.
The Bohr and von Neumann views on the measurement process in quantum mechanics have been interpreted for a long time in somewhat controversial terms, often leading to misconceptions. On the basis of some textual analysis, I would like to show that, contrary to a widespread opinion, their views should be taken less inconsistent, and much closer to each other, than usually thought. As a consequence, I claim that Bohr and von Neumann are conceptually on the same side on the issue of the universality of quantum mechanics: hopefully, this might contribute to a more accurate history of the measurement problem in quantum mechanics.
Emily F. Kerrison, Ron D. Ekers, John Morgan
et al.
Recent observations of interplanetary scintillation (IPS) at radio frequencies have proved to be a powerful tool for probing the solar environment from the ground. But how far back does this tradition really extend? Our survey of the literature to date has revealed a long history of scintillating observations, beginning with the oral traditions of Indigenous peoples from around the globe, encompassing the works of the Ancient Greeks and Renaissance scholars, and continuing right through into modern optics, astronomy and space science. We outline here the major steps that humanity has taken along this journey, using scintillation as a tool for predicting first terrestrial, and then space weather without ever having to leave the ground.
The existing literature on the construction costs of nuclear power reactors has focused almost exclusively on trends in construction costs in only two countries, the United States and France, and during two decades, the 1970s and 1980s. These analyses, Koomey and Hultman (2007); Grubler (2010), and Escobar-Rangel and Leveque (2015), study only 26% of reactors built globally between 1960 and 2010, providing an incomplete picture of the economic evolution of nuclear power construction. This study curates historical reactor-specific overnight construction cost (OCC) data that broaden the scope of study substantially, covering the full cost history for 349 reactors in the US, France, Canada, West Germany, Japan, India, and South Korea, encompassing 58% of all reactors built globally. We find that trends in costs have varied significantly in magnitude and in structure by era, country, and experience. In contrast to the rapid cost escalation that characterized nuclear construction in the United States, we find evidence of much milder cost escalation in many countries, including absolute cost declines in some countries and specific eras. Our new findings suggest that there is no inherent cost escalation trend associated with nuclear technology.
Anne M. Dupuy, Jean P. Cristol, Anne S. Bargnoux
et al.
Abstract Background and Aims Mobility and migration flows are growing from different countries of the world to European countries, including France and in particular the Mediterranean basin. This study aimed to investigate the presence of hemoglobin (Hb) variants in outpatients/inpatients of the Montpellier Hospital (France) in whom an HbA1c assay had been performed and for which the country of birth had been informed. Methods This is a retrospective study from January 2016 to December 2020 based on all high‐performance liquid chromatography (HPLC) chromatograms (Tosoh Bioscience HLC‐723G8) having an alarm of suspected Hb variant during HbA1c measurement. The corresponding samples were systematically sent to the hematology laboratory for confirmation and identification of Hb variant. Patient's medical history, clinical and demographic data were extracted from each medical chart. Statistical analyses were performed using XLSTAT® software, version 2016.06.35661. Results Three hundred sixty‐three patients were confirmed with Hb variant exhibiting 17 different Hb profiles, highlighting the pivotal role of glycated hemoglobin (HbA1c) as a detection step. The prevalence of Hb variant in this southern French population was 0.71%, with the highest frequency for the beta‐globin variants (n = 342/363; i.e., 94.2%), including the most common: S, C, E, and D in 200/342 (58.5%), 83/342 (24.3%), 29/342 (8.5%), and 11/342 (3.2%), respectively. Among patients with Hb variants, almost half (165/363; i.e., 45.4%) were born in the African continent with a predominance for Morocco (32/165; i.e., 19.3%) and Algeria (29/165; i.e., 17.5%). Conclusion HbA1c assay is a useful tool to detect Hb variants. Hemoglobinopathies are a public health issue in the current French population which is a multiethnic society. Despite the monocentric nature of our study, we note a high frequency of Hb variants in the south of France, which underlines the importance of screening for Hb variants in the whole population.
The year 2023 marks three anniversaries: the 150th anniversary of the French Physical Society, the 100th anniversary since the publication of Louis de Broglie's articles (the first fundamental articles of Quantum Mechanics) and the 50th anniversary of the Standard Model, the theory which describes in a unified framework the strong, the electromagnetic and the weak interactions among elementary particles. This note is an attempt to present the situation of theoretical physics in France during these years and highlight the french contributions in this world effort. We shall see that, although these contributions have been important, french theorists rarely played the leading roles. At the end I will try to draw some conclusions from these findings.
Matthieu Doutreligne, Adeline Degremont, Pierre-Alain Jachiet
et al.
Real World Data (RWD) bears great promises to improve the quality of care. However, specific infrastructures and methodologies are required to derive robust knowledge and brings innovations to the patient. Drawing upon the national case study of the 32 French regional and university hospitals governance, we highlight key aspects of modern Clinical Data Warehouses (CDWs): governance, transparency, types of data, data reuse, technical tools, documentation and data quality control processes. Semi-structured interviews as well as a review of reported studies on French CDWs were conducted in a semi-structured manner from March to November 2022. Out of 32 regional and university hospitals in France, 14 have a CDW in production, 5 are experimenting, 5 have a prospective CDW project, 8 did not have any CDW project at the time of writing. The implementation of CDW in France dates from 2011 and accelerated in the late 2020. From this case study, we draw some general guidelines for CDWs. The actual orientation of CDWs towards research requires efforts in governance stabilization, standardization of data schema and development in data quality and data documentation. Particular attention must be paid to the sustainability of the warehouse teams and to the multi-level governance. The transparency of the studies and the tools of transformation of the data must improve to allow successful multi-centric data reuses as well as innovations in routine care.
Among the rare materials of the Department of Manuscripts of the National Library of France (Bibliotheque nationale de France. Departement des Manuscrits. Supplement turc 515) there is a small chronicle of the anonymous author dating back to the era of the Crimean Khanate. The manuscript is provided with a description: “The history of the Crimean khans from 880 to 1191 from the Hegira (1475–1777), without a title and without the name of the author. The epigraph read on the front side of the first page is not a title, but a summary of the content of this work, which is not of particular importance. Dating: 1786–1800”. Although this chronicle is known thanks to the researches of a number of orientalists, nevertheless, for its full introduction into scientific circulation, its translation into Russian is of the uttermost necessity. The text processing will serve as the basis for the literary and artistic analysis of “The History of the Crimean Khans”.
We reconsider the classical equality 0.999. .. = 1 with the tool of circular words, that is: finite words whose last letter is assumed to be followed by the first one. Such circular words are naturally embedded with algebraic structures that enlight this problematic equality, allowing it to be considered in Q rather than in R. We comment early history of such structures, that involves English teachers and accountants of the first part of the xviii th century, who appear to be the firsts to assert the equality 0.999. .. = 1. Their level of understanding show links with Dubinsky et al.'s apos theory in mathematics education. Eventually, we rebuilt the field Q from circular words, and provide an original proof of the fact that an algebraic integer is either an integer or an irrational number.
Marie Leszczyńska, daughter of King Stanisław I and Catherine, née Opalińska, was the wife of King Louis XV of France between 1725 and 1768. This article examines the presence of Poles at her court and in her closest entourage. The queen could rely very little on her compatriots’ support within her household, for the only Poles who officially belonged to her court were confessors and a chef. The number of Polish residents associated with Versailles in regard to the frequency of their stays or the status they enjoyed at the court of King Louis XV was also very limited. Among them were the Queen’s parents and the princesse de Talmond. The most numerous among them were travellers, relatives of the Leszczyńskis and visitors who came to see the queen of France out of curiosity, a sense of duty or in the hope of obtaining assistance with a difficult financial situation. They were usually offered the privilege of an audience with the Queen and access to some court honours, but, with the exception of a small circle of people, Marie Leszczyńska did not offer guests from Poland the opportunity to become part of the court or to establish stronger cultural ties.