{"results":[{"id":"ss_380b37847a052a237091b16aeb55d46b4e56b8a7","title":"External Beam Radiation Therapy for Palliation of Symptomatic Bone Metastases: An ASTRO Clinical Practice Guideline.","authors":[{"name":"Sara Alcorn"},{"name":"Á. Cortés"},{"name":"Lisa Bradfield"},{"name":"M. Brennan"},{"name":"K. Dennis"},{"name":"D. Diaz"},{"name":"Yee-Cheen Doung"},{"name":"Shekinah N C Elmore"},{"name":"L. Hertan"},{"name":"C. Johnstone"},{"name":"Joshua A. Jones"},{"name":"N. Larrier"},{"name":"Simon S. Lo"},{"name":"Quynh-Nhu Nguyen"},{"name":"Yolanda D Tseng"},{"name":"D. Yerramilli"},{"name":"S. Zaky"},{"name":"Tracy Balboni"}],"abstract":"PURPOSE This guideline provides evidence-based recommendations for palliative external beam radiation therapy (RT) in symptomatic bone metastases. METHODS The American Society for Radiation Oncology (ASTRO) convened a task force to address 5 key questions regarding palliative RT in symptomatic bone metastases. Based on a systemic review by the Agency for Health Research and Quality, recommendations using predefined consensus-building methodology were established; evidence quality and recommendation strength were also assessed. RESULTS For palliative RT for symptomatic bone metastases, RT is recommended for managing pain from bone metastases and spine metastases with or without spinal cord or cauda equina compression. Regarding other modalities with RT, for patients with spine metastases causing spinal cord or cauda equina compression, surgery and postoperative RT are conditionally recommended over RT alone. Furthermore, dexamethasone is recommended for spine metastases with spinal cord or cauda equina compression. Patients with non-spine bone metastases requiring surgery are recommended postoperative RT. Symptomatic bone metastases treated with conventional RT are recommended 800 cGy in 1 fraction (800 cGy/1fx), 2000 cGy/5fx, 2400 cGy/6fx, or 3000 cGy/10fx. Spinal cord or cauda equina compression in patients ineligible for surgery and receiving conventional RT are recommended 800 cGy/1fx, 1600 cGy/2fx, 2000 cGy/5fx, or 3000 cGy/10fx. Symptomatic bone metastases in selected patients with good performance status without surgery or neurological symptoms/signs are conditionally recommended SBRT over conventional palliative RT. Spine bone metastases re-irradiated with conventional RT are recommended 800 cGy/1fx, 2000 cGy/5fx, 2400 cGy/6fx, or 2000 cGy/8fx; non-spine bone metastases re-irradiated with conventional RT are recommended 800 cGy/1fx, 2000 cGy/5fx, or 2400 cGy/6fx. Determination of an optimal RT approach/regimen requires whole person assessment, including prognosis, previous RT dose if applicable, risks to normal tissues, quality of life, cost implications, and patient goals and values. Relatedly, for patient-centered optimization of treatment-related toxicities and quality of life, shared decision-making is recommended. CONCLUSIONS Based on published data, the ASTRO task force's recommendations inform best clinical practices on palliative RT for symptomatic bone metastases.","source":"Semantic Scholar","year":2024,"language":"en","subjects":["Medicine"],"doi":"10.1016/j.prro.2024.04.018","url":"https://www.semanticscholar.org/paper/380b37847a052a237091b16aeb55d46b4e56b8a7","is_open_access":true,"citations":54,"published_at":"","score":69.62},{"id":"ss_a1cbe47d127f71a49debb39a52537fe1119dc861","title":"Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part I: Introduction and Treatment Decision-Making at the Time of Suspected Biochemical Recurrence after Radical Prostatectomy","authors":[{"name":"Todd M. Morgan"},{"name":"S. Boorjian"},{"name":"M. Buyyounouski"},{"name":"B. Chapin"},{"name":"David Y T Chen"},{"name":"Heather H. Cheng"},{"name":"Roger Chou"},{"name":"Heather A Jacene"},{"name":"Sophia C. Kamran"},{"name":"Sennett K. Kim"},{"name":"Erin Kirkby"},{"name":"A. Luckenbaugh"},{"name":"Ben J Nathanson"},{"name":"Y. Nyame"},{"name":"Edwin M Posadas"},{"name":"P. T. Tran"},{"name":"Ronald C. Chen"}],"abstract":"Purpose: The summary presented herein covers recommendations on salvage therapy for recurrent prostate cancer intended to facilitate care decisions and aid clinicians in caring for patients who have experienced a recurrence following prior treatment with curative intent. This is Part I of a three-part series focusing on treatment decision-making at the time of suspected biochemical recurrence (BCR) after radical prostatectomy (RP). Please refer to Part II for discussion of treatment delivery for non-metastatic BCR after RP and Part III for discussion of evaluation and management of recurrence after radiotherapy (RT) and focal therapy, regional recurrence, and oligometastasis. Materials and Methods: The systematic review that informs this Guideline was based on searches in Ovid MEDLINE (1946 to July 21, 2022), Cochrane Central Register of Controlled Trials (through August 2022), and Cochrane Database of Systematic Reviews (through August 2022). Update searches were conducted on July 26, 2023. Searches were supplemented by reviewing electronic database reference lists of relevant articles. Results: In a collaborative effort between AUA, ASTRO, and SUO, the Salvage Therapy for Prostate Cancer Panel developed evidence- and consensus-based statements to provide guidance for the care of patients who experience BCR after initial definitive local therapy for clinically localized disease. Conclusions: Advancing work in the area of diagnostic tools (particularly imaging), biomarkers, radiation delivery, and biological manipulation with the evolving armamentarium of therapeutic agents will undoubtedly present new opportunities for patients to experience long-term control of their cancer while minimizing toxicity.","source":"Semantic Scholar","year":2024,"language":"en","subjects":["Medicine"],"doi":"10.1097/JU.0000000000003892","url":"https://www.semanticscholar.org/paper/a1cbe47d127f71a49debb39a52537fe1119dc861","is_open_access":true,"citations":50,"published_at":"","score":69.5},{"id":"ss_13ac800d9b6206d2a0664340ce6cc3a3ec4a367e","title":"ASTRO: Teaching Language Models to Reason by Reflecting and Backtracking In-Context","authors":[{"name":"Joongwon Kim"},{"name":"Anirudh Goyal"},{"name":"Liang Tan"},{"name":"Hanna Hajishirzi"},{"name":"Srini Iyer"},{"name":"Tianlu Wang"}],"abstract":"We introduce ASTRO, the\"Autoregressive Search-Taught Reasoner\", a framework for training language models to reason like search algorithms, explicitly leveraging self-reflection, backtracking, and exploration in their outputs. Recently, training large language models (LLMs) via reinforcement learning (RL) has led to the advent of reasoning models with greatly enhanced reasoning capabilities. Open-source replications of reasoning models, while successful, build upon models that already exhibit strong reasoning capabilities along with search behavior observed even before RL. As a result, it is yet unclear how to boost the reasoning capabilities of other non-reasoner models including Llama 3. ASTRO teaches such models to internalize structured search behavior through a synthetic dataset derived from Monte Carlo Tree Search (MCTS) over mathematical problem-solving trajectories. By converting search traces into natural language chain-of-thoughts that capture both successes and recoveries from failure, ASTRO bootstraps models with a rich prior for exploration during RL. We finetune our models on these search-derived traces and further improve performance via RL with verifiable rewards. We apply ASTRO to the Llama 3 family of models and achieve absolute performance gains of 16.0% on MATH-500, 26.9% on AMC 2023, and 20.0% on AIME 2024, especially improving upon challenging problems that require iterative correction. Our results demonstrate that search-inspired training offers a principled way to instill robust reasoning capabilities into open LLMs.","source":"Semantic Scholar","year":2025,"language":"en","subjects":["Computer Science"],"doi":"10.48550/arXiv.2507.00417","url":"https://www.semanticscholar.org/paper/13ac800d9b6206d2a0664340ce6cc3a3ec4a367e","is_open_access":true,"citations":5,"published_at":"","score":69.15},{"id":"ss_32827ded439585838b92b6708a04c2add4c89c54","title":"Radiation Therapy for HPV-Positive Oropharyngeal Squamous Cell Carcinoma: An ASTRO Clinical Practice Guideline.","authors":[{"name":"D. Margalit"},{"name":"C. Anker"},{"name":"M. Aristophanous"},{"name":"M. Awan"},{"name":"Gopal K Bajaj"},{"name":"Lisa Bradfield"},{"name":"Joseph A. Califano"},{"name":"Jimmy J Caudell"},{"name":"Christina H Chapman"},{"name":"A. Garden"},{"name":"P. Harari"},{"name":"Amanda R. Helms"},{"name":"Alexander Lin"},{"name":"E. Maghami"},{"name":"Ranee Mehra"},{"name":"L. Parker"},{"name":"Y. Shnayder"},{"name":"Sharon A. Spencer"},{"name":"P. Swiecicki"},{"name":"Jillian Tsai"},{"name":"David J Sher"}],"abstract":"PURPOSE Human Papilloma Virus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is a distinct disease from other head and neck tumors. This guideline provides evidence-based recommendations on the critical decisions in its curative treatment, including both definitive and postoperative radiation therapy (RT) management. METHODS ASTRO convened a task force to address 5 key questions on the use of RT for management of HPV-associated OPSCC. These questions included indications for definitive and postoperative RT and chemoradiation; dose-fractionation regimens and treatment volumes; preferred RT techniques and normal tissue considerations; and posttreatment management decisions. The task force did not address indications for primary surgery versus RT. Recommendations were based on a systematic literature review and created using a predefined consensus-building methodology and system for grading evidence quality and recommendation strength. RESULTS Concurrent cisplatin is recommended for patients receiving definitive RT with T3-4 disease and/or 1 node \u003e3 cm, or multiple nodes. For similar patients who are ineligible for cisplatin, concurrent cetuximab, carboplatin/5-fluorouracil, or taxane-based systemic therapy are conditionally recommended. In the postoperative setting, RT with concurrent cisplatin (either schedule) is recommended for positive surgical margins or extranodal extension. Postoperative RT alone is recommended for pT3-4 disease, \u003e2 nodes, or a single node \u003e3 cm. Observation is conditionally recommended for pT1-2 disease and a single node ≤3 cm without other risk factors. For patients treated with definitive RT with concurrent systemic therapy, 7000 cGy in 33 to 35 fractions is recommended, and for patients receiving postoperative RT without positive surgical margins and extranodal extension, 5600 to 6000 cGy is recommended. For all patients receiving RT, intensity modulated RT over 3-dimensional techniques with reduction in dose to critical organs at risk (including salivary and swallowing structures) is recommended. Reassessment with positron emission tomography-computed tomography is recommended approximately 3 months after definitive RT/chemoradiation, and neck dissection is recommended for convincing evidence of residual disease; for equivocal positron emission tomography-computed tomography findings, either neck dissection or repeat imaging is recommended. CONCLUSIONS The role and practice of RT continues to evolve for HPV-associated OPSCC, and these guidelines inform best clinical practice based on the available evidence.","source":"Semantic Scholar","year":2024,"language":"en","subjects":["Medicine"],"doi":"10.1016/j.prro.2024.05.007","url":"https://www.semanticscholar.org/paper/32827ded439585838b92b6708a04c2add4c89c54","pdf_url":"http://www.practicalradonc.org/article/S1879850024001395/pdf","is_open_access":true,"citations":36,"published_at":"","score":69.08},{"id":"ss_e643441c1f39e0e5c24c3bf832ad935ea7afabaa","title":"Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part II: Treatment Delivery for Non-metastatic Biochemical Recurrence After Primary Radical Prostatectomy","authors":[{"name":"Todd M. Morgan"},{"name":"S. Boorjian"},{"name":"M. Buyyounouski"},{"name":"B. Chapin"},{"name":"David Y T Chen"},{"name":"Heather H. Cheng"},{"name":"Roger Chou"},{"name":"Heather A Jacene"},{"name":"Sophia C. Kamran"},{"name":"Sennett K. Kim"},{"name":"Erin Kirkby"},{"name":"A. Luckenbaugh"},{"name":"Ben J Nathanson"},{"name":"Y. Nyame"},{"name":"Edwin M Posadas"},{"name":"P. T. Tran"},{"name":"Ronald C. Chen"}],"abstract":"Purpose: The summary presented herein covers recommendations on salvage therapy for recurrent prostate cancer intended to facilitate care decisions and aid clinicians in caring for patients who have experienced a recurrence following prior treatment with curative intent. This is Part II of a three-part series focusing on treatment delivery for non-metastatic biochemical recurrence (BCR) after primary radical prostatectomy (RP). Please refer to Part I for discussion of treatment decision-making and Part III for discussion of evaluation and management of recurrence after radiotherapy (RT) and focal therapy, regional recurrence, and oligometastasis. Materials and Methods: The systematic review that informs this Guideline was based on searches in Ovid MEDLINE (1946 to July 21, 2022), Cochrane Central Register of Controlled Trials (through August 2022), and Cochrane Database of Systematic Reviews (through August 2022). Update searches were conducted on July 26, 2023. Searches were supplemented by reviewing electronic database reference lists of relevant articles. Results: In a collaborative effort between AUA, ASTRO, and SUO, the Salvage Therapy for Prostate Cancer Panel developed evidence- and consensus-based guideline statements to provide guidance for the care of patients who experience BCR after initial definitive local therapy for clinically localized disease. Conclusions: Optimizing and personalizing the approach to salvage therapy remains an ongoing area of work in the field of genitourinary oncology and represents an area of research and clinical care that requires well-coordinated, multi-disciplinary efforts.","source":"Semantic Scholar","year":2024,"language":"en","subjects":["Medicine"],"doi":"10.1097/JU.0000000000003891","url":"https://www.semanticscholar.org/paper/e643441c1f39e0e5c24c3bf832ad935ea7afabaa","is_open_access":true,"citations":27,"published_at":"","score":68.81},{"id":"ss_17cf380d5effb1ad6f565613d25f17eb393129ef","title":"Radiation Therapy Summary of the AUA/ASTRO Guideline on Clinically Localized Prostate Cancer.","authors":[{"name":"C. Deville"},{"name":"Sophia C. Kamran"},{"name":"Scott C. Morgan"},{"name":"K. Yamoah"},{"name":"N. Vapiwala"}],"abstract":"PURPOSE Our purpose was to develop a summary of recommendations regarding the management of patients with clinically localized prostate cancer based on the American Urologic Association/ ASTRO Guideline on Clinically Localized Prostate Cancer. METHODS The American Urologic Association and ASTRO convened a multidisciplinary, expert panel to develop recommendations based on a systematic literature review using an a priori defined consensus-building methodology. The topics covered were risk assessment, staging, risk-based management, principles of management including active surveillance, surgery, radiation, and follow-up after treatment. Presented are recommendations from the guideline most pertinent to radiation oncologists with an additional statement on health equity, diversity, and inclusion related to guideline panel composition and the topic of clinically localized prostate cancer. SUMMARY Staging, risk assessment, and management options in prostate cancer have advanced over the last decade and significantly affect shared decision-making for treatment management. Current advancements and controversies discussed to guide staging, risk assessment, and treatment recommendations include the use of advanced imaging and tumor genomic profiling. An essential active surveillance strategy includes prostate-specific antigen monitoring and periodic digital rectal examination with changes triggering magnetic resonance imaging and possible biopsy thereafter and histologic progression or greater tumor volume prompting consideration of definitive local treatment. The panel recommends against routine use of adjuvant radiation therapy (RT) for patients with prostate cancer after prostatectomy with negative nodes and an undetectable prostate-specific antigen, while acknowledging that patients at highest risk of recurrence were relatively poorly represented in the 3 largest randomized trials comparing adjuvant RT to early salvage and that a role may exist for adjuvant RT in selected patients at highest risk. RT for clinically localized prostate cancer has evolved rapidly, with new trial results, therapeutic combinations, and technological advances. The recommendation of moderately hypofractionated RT has not changed, and the updated guideline incorporates a conditional recommendation for the use of ultrahypofractionated treatment. Health disparities and inequities exist in the management of clinically localized prostate cancer across the continuum of care that can influence guideline concordance.","source":"Semantic Scholar","year":2024,"language":"en","subjects":["Medicine"],"doi":"10.1016/j.prro.2023.09.007","url":"https://www.semanticscholar.org/paper/17cf380d5effb1ad6f565613d25f17eb393129ef","pdf_url":"http://www.practicalradonc.org/article/S1879850023002758/pdf","is_open_access":true,"citations":18,"published_at":"","score":68.53999999999999},{"id":"ss_76fe995de2a5886df50659c275631feeab092386","title":"CompOSE reference manual","authors":[{"name":"S. Typel"},{"name":"M. Oertel"},{"name":"T. Klähn"},{"name":"D. Chatterjee"},{"name":"V. Dexheimer"},{"name":"C. Ishizuka"},{"name":"M. Mancini"},{"name":"J. Novak"},{"name":"H. Pais"},{"name":"C. Providência"},{"name":"Ad. R. Raduta"},{"name":"M. Servillat"},{"name":"L. Tolos"}],"abstract":"CompOSE (CompStar Online Supernovae Equations of State) is an online repository of equations of state (EoS) for use in nuclear physics and astrophysics, e.g., in the description of compact stars or the simulation of core-collapse supernovae and neutron-star mergers, see https://compose.obspm.fr. The main services, offered via the website, are: a collection of data tables in a flexible and easily extendable data format for different EoS types and related physical quantities with extensive documentation and referencing; software for download to extract and to interpolate these data and to calculate additional quantities; webtools to generate EoS tables that are customized to the needs of the users and to illustrate dependencies of various EoS quantities in graphical form. This manual is an update of previous versions that are available on the CompOSE website, at arXiv:1307.5715 [astro-ph.SR], and that was originally published in the journal “Physics of Particles and Nuclei” with doi:10.1134/S1063779615040061. It contains a detailed description of the service, containing a general introduction as well as instructions for potential contributors and for users. Short versions of the manual for EoS users and providers will also be available as separate publications.","source":"Semantic Scholar","year":2022,"language":"en","subjects":["Physics"],"doi":"10.1140/epja/s10050-022-00847-y","url":"https://www.semanticscholar.org/paper/76fe995de2a5886df50659c275631feeab092386","pdf_url":"https://link.springer.com/content/pdf/10.1140/epja/s10050-022-00847-y.pdf","is_open_access":true,"citations":75,"published_at":"","score":68.25},{"id":"ss_aae4898b6aa86d3b1c776b95cb7fe59a10ce0138","title":"Galaxy growth in a massive halo in the first billion years of cosmic history","authors":[{"name":"D. Marrone"},{"name":"J. Spilker"},{"name":"C. Hayward"},{"name":"J. Vieira"},{"name":"M. Aravena"},{"name":"M. Ashby"},{"name":"M. Bayliss"},{"name":"M. Béthermin"},{"name":"M. Brodwin"},{"name":"M. Bothwell"},{"name":"J. Carlstrom"},{"name":"S. Chapman"},{"name":"Chian-Chou Chen"},{"name":"T. Crawford"},{"name":"D. Cunningham"},{"name":"C. Breuck"},{"name":"C. Fassnacht"},{"name":"A. Gonzalez"},{"name":"T. Greve"},{"name":"Y. Hezaveh"},{"name":"K. Lacaille"},{"name":"K. Litke"},{"name":"S. Lower"},{"name":"J. Ma"},{"name":"M. Malkan"},{"name":"T. Miller"},{"name":"W. Morningstar"},{"name":"E. Murphy"},{"name":"D. Narayanan"},{"name":"K. Phadke"},{"name":"K. Rotermund"},{"name":"J. Sreevani"},{"name":"B. Stalder"},{"name":"A. Stark"},{"name":"M. Strandet"},{"name":"M. Tang"},{"name":"A. Arizona"},{"name":"Flatiron"},{"name":"Cfa"},{"name":"Illinois."},{"name":"Udp"},{"name":"Mit"},{"name":"Marseille"},{"name":"Umkc"},{"name":"Cavendish"},{"name":"Kicc"},{"name":"Kicp"},{"name":"UChicago Phys"},{"name":"UChicago Efi"},{"name":"UChicago Astro"},{"name":"Dalhousie"},{"name":"Eső"},{"name":"Saint Mary’s"},{"name":"UCDavis"},{"name":"Florida"},{"name":"Ucl"},{"name":"Kipac"},{"name":"McMaster"},{"name":"Ucla"},{"name":"Nrao"},{"name":"Lsst"},{"name":"Mpifr"},{"name":"IMPRS-Bonn"},{"name":"Hubble Fellow"}],"abstract":"According to the current understanding of cosmic structure formation, the precursors of the most massive structures in the Universe began to form shortly after the Big Bang, in regions corresponding to the largest fluctuations in the cosmic density field. Observing these structures during their period of active growth and assembly—the first few hundred million years of the Universe—is challenging because it requires surveys that are sensitive enough to detect the distant galaxies that act as signposts for these structures and wide enough to capture the rarest objects. As a result, very few such objects have been detected so far. Here we report observations of a far-infrared-luminous object at redshift 6.900 (less than 800 million years after the Big Bang) that was discovered in a wide-field survey. High-resolution imaging shows it to be a pair of extremely massive star-forming galaxies. The larger is forming stars at a rate of 2,900 solar masses per year, contains 270 billion solar masses of gas and 2.5 billion solar masses of dust, and is more massive than any other known object at a redshift of more than 6. Its rapid star formation is probably triggered by its companion galaxy at a projected separation of 8 kiloparsecs. This merging companion hosts 35 billion solar masses of stars and has a star-formation rate of 540 solar masses per year, but has an order of magnitude less gas and dust than its neighbour and physical conditions akin to those observed in lower-metallicity galaxies in the nearby Universe. These objects suggest the presence of a dark-matter halo with a mass of more than 100 billion solar masses, making it among the rarest dark-matter haloes that should exist in the Universe at this epoch.","source":"Semantic Scholar","year":2017,"language":"en","subjects":["Medicine","Physics"],"doi":"10.1038/nature24629","url":"https://www.semanticscholar.org/paper/aae4898b6aa86d3b1c776b95cb7fe59a10ce0138","pdf_url":"https://repository.arizona.edu/bitstream/10150/627936/1/spt0311disc.pdf","is_open_access":true,"citations":166,"published_at":"","score":65.98},{"id":"ss_a7d1ec91c524af1adfdb652c431a67834f159a54","title":"Hitomi (ASTRO-H) X-ray Astronomy Satellite","authors":[{"name":"Tadayuki Takahashi"},{"name":"M. Kokubun"},{"name":"K. Mitsuda"},{"name":"R. Kelley"},{"name":"T. Ohashi"},{"name":"F. Aharonian"},{"name":"H. Akamatsu"},{"name":"F. Akimoto"},{"name":"S. Allen"},{"name":"N. Anabuki"},{"name":"L. Angelini"},{"name":"K. Arnaud"},{"name":"M. Asai"},{"name":"M. Audard"},{"name":"H. Awaki"},{"name":"M. Axelsson"},{"name":"P. Azzarello"},{"name":"C. Baluta"},{"name":"A. Bamba"},{"name":"N. Bando"},{"name":"M. Bautz"},{"name":"T. Bialas"},{"name":"R. Blandford"},{"name":"K. Boyce"},{"name":"L. Brenneman"},{"name":"G. Brown"},{"name":"E. Bulbul"},{"name":"E. Cackett"},{"name":"E. Canavan"},{"name":"M. Chernyakova"},{"name":"M. Chiao"},{"name":"P. Coppi"},{"name":"E. Costantini"},{"name":"Steve O’ Dell"},{"name":"M. Dipirro"},{"name":"C. Done"},{"name":"T. Dotani"},{"name":"J. Doty"},{"name":"K. Ebisawa"},{"name":"M. Eckart"},{"name":"T. Enoto"},{"name":"Y. Ezoe"},{"name":"Andrew C. Fabian"},{"name":"C. Ferrigno"},{"name":"A. Foster"},{"name":"R. Fujimoto"},{"name":"Y. Fukazawa"},{"name":"S. Funk"},{"name":"A. Furuzawa"},{"name":"M. Galeazzi"},{"name":"L. Gallo"},{"name":"P. Gandhi"},{"name":"K. Gilmore"},{"name":"M. Giustini"},{"name":"A. Goldwurm"},{"name":"L. Gu"},{"name":"M. Guainazzi"},{"name":"D. Haas"},{"name":"Y. Haba"},{"name":"K. Hagino"},{"name":"K. Hamaguchi"},{"name":"I. Harrus"},{"name":"I. Hatsukade"},{"name":"T. Hayashi"},{"name":"K. Hayashi"},{"name":"K. Hayashida"},{"name":"J. D. den Herder"},{"name":"J. Hiraga"},{"name":"K. Hirose"},{"name":"A. Hornschemeier"},{"name":"A. Hoshino"},{"name":"J. Hughes"},{"name":"Y. Ichinohe"},{"name":"R. Iizuka"},{"name":"H. Inoue"},{"name":"Y. Inoue"},{"name":"K. Ishibashi"},{"name":"M. Ishida"},{"name":"K. Ishikawa"},{"name":"K. Ishimura"},{"name":"Y. Ishisaki"},{"name":"M. Itoh"},{"name":"M. Iwai"},{"name":"N. Iwata"},{"name":"N. Iyomoto"},{"name":"C. Jewell"},{"name":"J. Kaastra"},{"name":"T. Kallman"},{"name":"T. Kamae"},{"name":"E. Kara"},{"name":"J. Kataoka"},{"name":"S. Katsuda"},{"name":"J. Katsuta"},{"name":"Madoka Kawaharada"},{"name":"N. Kawai"},{"name":"T. Kawano"},{"name":"S. Kawasaki"},{"name":"D. Khangulyan"},{"name":"C. Kilbourne"},{"name":"M. Kimball"},{"name":"A. King"},{"name":"T. Kitaguchi"},{"name":"S. Kitamoto"},{"name":"T. Kitayama"},{"name":"T. Kohmura"},{"name":"S. Konami"},{"name":"T. Kosaka"},{"name":"A. Koujelev"},{"name":"K. Koyama"},{"name":"S. Koyama"},{"name":"P. Kretschmar"},{"name":"H. Krimm"},{"name":"Aya Kubota"},{"name":"H. Kunieda"},{"name":"P. Laurent"},{"name":"Shiu-Hang Lee"},{"name":"M. Leutenegger"},{"name":"O. Limousin"},{"name":"M. Loewenstein"},{"name":"K. Long"},{"name":"D. Lumb"},{"name":"G. Madejski"},{"name":"Y. Maeda"},{"name":"D. Maier"},{"name":"K. Makishima"},{"name":"M. Markevitch"},{"name":"Candace Masters"},{"name":"H. Matsumoto"},{"name":"Kyoko Matsushita"},{"name":"D. McCammon"},{"name":"D. Mcguinness"},{"name":"B. McNamara"},{"name":"M. Mehdipour"},{"name":"J. Miko"},{"name":"E. Miller"},{"name":"Jonathan M. Miller"},{"name":"S. Mineshige"},{"name":"K. Minesugi"},{"name":"I. Mitsuishi"},{"name":"T. Miyazawa"},{"name":"T. Mizuno"},{"name":"H. Mori"},{"name":"K. Mori"},{"name":"Franco Moroso"},{"name":"H. Moseley"},{"name":"Theodore Muench"},{"name":"K. Mukai"},{"name":"H. Murakami"},{"name":"T. Murakami"},{"name":"R. Mushotzky"},{"name":"H. Nagano"},{"name":"Ryo Nagino"},{"name":"T. Nakagawa"},{"name":"H. Nakajima"},{"name":"T. Nakamori"},{"name":"T. Nakano"},{"name":"Shinya Nakashima"},{"name":"K. Nakazawa"},{"name":"Y. Namba"},{"name":"C. Natsukari"},{"name":"Y. Nishioka"},{"name":"K. Nobukawa"},{"name":"M. Nobukawa"},{"name":"H. Noda"},{"name":"M. Nomachi"},{"name":"H. Odaka"},{"name":"H. Ogawa"},{"name":"M. Ogawa"},{"name":"K. Ogi"},{"name":"M. Ohno"},{"name":"M. Ohta"},{"name":"T. Okajima"},{"name":"A. Okamoto"},{"name":"T. Okazaki"},{"name":"N. Ota"},{"name":"M. Ozaki"},{"name":"F. Paerels"},{"name":"S. Paltani"},{"name":"A. Parmar"},{"name":"R. Petre"},{"name":"C. Pinto"},{"name":"J. de Plaa"},{"name":"M. Pohl"},{"name":"J. Pontius"},{"name":"F. Porter"},{"name":"K. Pottschmidt"},{"name":"B. Ramsey"},{"name":"C. Reynolds"},{"name":"H. Russell"},{"name":"S. Safi-Harb"},{"name":"S. Saito"},{"name":"K. Sakai"},{"name":"S. Sakai"},{"name":"H. Sameshima"},{"name":"T. Sasaki"},{"name":"G. Sato"},{"name":"Kosuke Sato"},{"name":"R. Sato"},{"name":"Yoichi Sato"},{"name":"M. Sawada"},{"name":"N. Schartel"},{"name":"P. Serlemitsos"},{"name":"H. Seta"},{"name":"Y. Shibano"},{"name":"M. Shida"},{"name":"M. Shidatsu"},{"name":"T. Shimada"},{"name":"K. Shinozaki"},{"name":"P. Shirron"},{"name":"A. Simionescu"},{"name":"C. Simmons"},{"name":"Randall K. Smith"},{"name":"G. Sneiderman"},{"name":"Y. Soong"},{"name":"Ł. Stawarz"},{"name":"Y. Sugawara"},{"name":"S. Sugita"},{"name":"H. Sugita"},{"name":"A. Szymkowiak"},{"name":"H. Tajima"},{"name":"H. Takahashi"},{"name":"S. Takeda"},{"name":"Y. Takei"},{"name":"T. Tamagawa"},{"name":"T. Tamura"},{"name":"K. Tamura"},{"name":"Takaaki Tanaka"},{"name":"Yasuo Tanaka"},{"name":"Yasuyuki T. Tanaka"},{"name":"M. Tashiro"},{"name":"Y. Tawara"},{"name":"Y. Terada"},{"name":"Yuichi Terashima"},{"name":"F. Tombesi"},{"name":"H. Tomida"},{"name":"Y. Tsuboi"},{"name":"M. Tsujimoto"},{"name":"H. Tsunemi"},{"name":"T. Tsuru"},{"name":"H. Uchida"},{"name":"H. Uchiyama"},{"name":"Yasunobu Uchiyama"},{"name":"S. Ueda"},{"name":"Y. Ueda"},{"name":"S. Ueno"},{"name":"S. Uno"},{"name":"C. M. Urry"},{"name":"E. Ursino"},{"name":"C. D. de Vries"},{"name":"A. Wada"},{"name":"S. Watanabe"},{"name":"Tomomi Watanabe"},{"name":"N. Werner"},{"name":"D. Wik"},{"name":"D. Wilkins"},{"name":"B. Williams"},{"name":"S. Yamada"},{"name":"Takahiro Yamada"},{"name":"H. Yamaguchi"},{"name":"K. Yamaoka"},{"name":"N. Yamasaki"},{"name":"M. Yamauchi"},{"name":"S. Yamauchi"},{"name":"T. Yaqoob"},{"name":"Y. Yatsu"},{"name":"D. Yonetoku"},{"name":"A. Yoshida"},{"name":"T. Yuasa"},{"name":"I. Zhuravleva"},{"name":"A. Zoghbi"}],"abstract":"Abstract. The Hitomi (ASTRO-H) mission is the sixth Japanese x-ray astronomy satellite developed by a large international collaboration, including Japan, USA, Canada, and Europe. The mission aimed to provide the highest energy resolution ever achieved at E  \u003e  2  keV, using a microcalorimeter instrument, and to cover a wide energy range spanning four decades in energy from soft x-rays to gamma rays. After a successful launch on February 17, 2016, the spacecraft lost its function on March 26, 2016, but the commissioning phase for about a month provided valuable information on the onboard instruments and the spacecraft system, including astrophysical results obtained from first light observations. The paper describes the Hitomi (ASTRO-H) mission, its capabilities, the initial operation, and the instruments/spacecraft performances confirmed during the commissioning operations for about a month.","source":"Semantic Scholar","year":2018,"language":"en","subjects":["Engineering"],"doi":"10.1117/1.JATIS.4.2.021402","url":"https://www.semanticscholar.org/paper/a7d1ec91c524af1adfdb652c431a67834f159a54","pdf_url":"https://www.spiedigitallibrary.org/journals/Journal-of-Astronomical-Telescopes-Instruments-and-Systems/volume-4/issue-2/021402/Hitomi-ASTRO-H-X-ray-Astronomy-Satellite/10.1117/1.JATIS.4.2.021402.pdf","is_open_access":true,"citations":100,"published_at":"","score":65},{"id":"crossref_10.1108/sr-06-2017-0104","title":"Aqua-gel pH sensor: intelligent engineering and evaluation of pH sensor based on multi-factorial testing regimes","authors":[{"name":"Mariam Mir"},{"name":"Murtaza Najabat Ali"},{"name":"Umar Ansari"},{"name":"Patrick J. Smith"},{"name":"Amber Zahoor"},{"name":"Faisal Qayyum"},{"name":"Sabtain Abbas"}],"abstract":"PurposeThe fabrication and characterization of a hydrogel-based conductometric sensor have been carried out. The purpose of this research is to fabricate a small robust hydrogel-based conductometric sensor for real-time monitoring of pH in the physiological range.Design/methodology/approachA pH-responsive Chitosan/Gelatin composite hydrogel has been used for this purpose. This study reports and analyzes the sensing response obtained from four hydrogel compositions with varying Chitosan/Gelatin ratios. The pH-responsive nature of the hydrogel has been mapped out through volumetric and conductometric tests. An attempt has been made to correlate these characteristics with the physico-chemical nature of the hydrogel through scanning electron microscopy, Fourier transform infrared spectroscopy and X-ray diffraction techniques.FindingsThe four hydrogel compositions differed on the basis of gel composition ratios; the conductometric analysis results prove that the sensor with the hydrogel composition (Chitosan 2 per cent, Gelatin 7 per cent, ratio 1:2) produces the best pH resolution in the pH range of 4 to 9. The sensing mechanisms and the differences obtained between individual sensor outputs have been discussed in detail. On the basis of this extensivein vitroassessment, it has been concluded that while key pendant functional groups contribute to pH-responsive characteristics of the hydrogel, the overall sensitivity of the sensors gel component to surrounding pH is also determined by the crystalline to amorphous ratio of the hydrogel composite, its interpenetrating cross-linked structure and the relative ratio of the hydrophilic to the pH-sensitive components.Practical implicationsThe conductometric sensor results prove that the fabricated sensor with the shortlisted hydrogel composition shows good sensitivity in the physiological pH range (4 to 9) and it has the potential for use in point of care medical devices for diagnostic purposes.Originality/valueThis is the first reported version of the fabrication and testing and analysis/comparison of a hydrogel-based conductometric sensor based on this composition. The work is original and has not been replicated anywhere.","source":"CrossRef","year":2019,"language":"en","subjects":null,"doi":"10.1108/sr-06-2017-0104","url":"https://doi.org/10.1108/sr-06-2017-0104","is_open_access":true,"citations":6,"published_at":"","score":63.18},{"id":"ss_d876843e70c19c6e769cf64381b0e4153173360f","title":"The ASTRO-H (Hitomi) x-ray astronomy satellite","authors":[{"name":"Tadayuki Takahashi"},{"name":"M. Kokubun"},{"name":"K. Mitsuda"},{"name":"R. Kelley"},{"name":"T. Ohashi"},{"name":"F. Aharonian"},{"name":"H. Akamatsu"},{"name":"F. Akimoto"},{"name":"S. Allen"},{"name":"N. Anabuki"},{"name":"L. Angelini"},{"name":"K. Arnaud"},{"name":"M. Asai"},{"name":"M. Audard"},{"name":"H. Awaki"},{"name":"M. Axelsson"},{"name":"P. Azzarello"},{"name":"C. Baluta"},{"name":"A. Bamba"},{"name":"N. Bando"},{"name":"M. Bautz"},{"name":"T. Bialas"},{"name":"R. Blandford"},{"name":"K. Boyce"},{"name":"L. Brenneman"},{"name":"G. Brown"},{"name":"E. Bulbul"},{"name":"E. Cackett"},{"name":"E. Canavan"},{"name":"M. Chernyakova"},{"name":"M. Chiao"},{"name":"P. Coppi"},{"name":"E. Costantini"},{"name":"J. de Plaa"},{"name":"J. D. den Herder"},{"name":"M. Dipirro"},{"name":"C. Done"},{"name":"T. Dotani"},{"name":"J. Doty"},{"name":"K. Ebisawa"},{"name":"M. Eckart"},{"name":"T. Enoto"},{"name":"Y. Ezoe"},{"name":"A. Fabian"},{"name":"C. Ferrigno"},{"name":"A. Foster"},{"name":"R. Fujimoto"},{"name":"Y. Fukazawa"},{"name":"A. Furuzawa"},{"name":"M. Galeazzi"},{"name":"L. Gallo"},{"name":"P. Gandhi"},{"name":"K. Gilmore"},{"name":"M. Giustini"},{"name":"A. Goldwurm"},{"name":"L. Gu"},{"name":"M. Guainazzi"},{"name":"D. Haas"},{"name":"Y. Haba"},{"name":"K. Hagino"},{"name":"K. Hamaguchi"},{"name":"A. Harayama"},{"name":"I. Harrus"},{"name":"I. Hatsukade"},{"name":"T. Hayashi"},{"name":"K. Hayashi"},{"name":"K. Hayashida"},{"name":"J. Hiraga"},{"name":"K. Hirose"},{"name":"A. Hornschemeier"},{"name":"A. Hoshino"},{"name":"J. Hughes"},{"name":"Y. Ichinohe"},{"name":"R. Iizuka"},{"name":"Y. Inoue"},{"name":"H. Inoue"},{"name":"K. Ishibashi"},{"name":"M. Ishida"},{"name":"K. Ishikawa"},{"name":"K. Ishimura"},{"name":"Y. Ishisaki"},{"name":"M. Itoh"},{"name":"N. Iwata"},{"name":"N. Iyomoto"},{"name":"C. Jewell"},{"name":"J. Kaastra"},{"name":"T. Kallman"},{"name":"T. Kamae"},{"name":"E. Kara"},{"name":"J. Kataoka"},{"name":"S. Katsuda"},{"name":"J. Katsuta"},{"name":"Madoka Kawaharada"},{"name":"N. Kawai"},{"name":"T. Kawano"},{"name":"S. Kawasaki"},{"name":"D. Khangulyan"},{"name":"C. Kilbourne"},{"name":"M. Kimball"},{"name":"A. King"},{"name":"T. Kitaguchi"},{"name":"S. Kitamoto"},{"name":"T. Kitayama"},{"name":"T. Kohmura"},{"name":"T. Kosaka"},{"name":"A. Koujelev"},{"name":"K. Koyama"},{"name":"S. Koyama"},{"name":"P. Kretschmar"},{"name":"H. Krimm"},{"name":"A. Kubota"},{"name":"H. Kunieda"},{"name":"P. Laurent"},{"name":"F. Lebrun"},{"name":"Shiu-Huang Lee"},{"name":"M. Leutenegger"},{"name":"O. Limousin"},{"name":"M. Loewenstein"},{"name":"K. Long"},{"name":"D. Lumb"},{"name":"G. Madejski"},{"name":"Y. Maeda"},{"name":"D. Maier"},{"name":"K. Makishima"},{"name":"M. Markevitch"},{"name":"Candace Masters"},{"name":"H. Matsumoto"},{"name":"K. Matsushita"},{"name":"D. McCammon"},{"name":"D. Mcguinness"},{"name":"B. McNamara"},{"name":"M. Mehdipour"},{"name":"J. Miko"},{"name":"Jonathan M. Miller"},{"name":"E. Miller"},{"name":"S. Mineshige"},{"name":"K. Minesugi"},{"name":"I. Mitsuishi"},{"name":"T. Miyazawa"},{"name":"T. Mizuno"},{"name":"K. Mori"},{"name":"H. Mori"},{"name":"Franco Moroso"},{"name":"H. Moseley"},{"name":"Theodore Muench"},{"name":"K. Mukai"},{"name":"H. Murakami"},{"name":"T. Murakami"},{"name":"R. Mushotzky"},{"name":"H. Nagano"},{"name":"Ryo Nagino"},{"name":"T. Nakagawa"},{"name":"H. Nakajima"},{"name":"T. Nakamori"},{"name":"T. Nakano"},{"name":"S. Nakashima"},{"name":"K. Nakazawa"},{"name":"Y. Namba"},{"name":"C. Natsukari"},{"name":"Y. Nishioka"},{"name":"M. Nobukawa"},{"name":"K. Nobukawa"},{"name":"H. Noda"},{"name":"M. Nomachi"},{"name":"S. O’Dell"},{"name":"H. Odaka"},{"name":"H. Ogawa"},{"name":"M. Ogawa"},{"name":"K. Ogi"},{"name":"M. Ohno"},{"name":"M. Ohta"},{"name":"T. Okajima"},{"name":"A. Okamoto"},{"name":"T. Okazaki"},{"name":"N. Ota"},{"name":"M. Ozaki"},{"name":"F. Paerels"},{"name":"S. Paltani"},{"name":"A. Parmar"},{"name":"R. Petre"},{"name":"C. Pinto"},{"name":"M. Pohl"},{"name":"J. Pontius"},{"name":"F. Porter"},{"name":"K. Pottschmidt"},{"name":"B. Ramsey"},{"name":"C. Reynolds"},{"name":"H. Russell"},{"name":"S. Safi-Harb"},{"name":"S. Saito"},{"name":"S. Sakai"},{"name":"K. Sakai"},{"name":"H. Sameshima"},{"name":"T. Sasaki"},{"name":"G. Sato"},{"name":"Yoichi Sato"},{"name":"Kosuke Sato"},{"name":"R. Sato"},{"name":"M. Sawada"},{"name":"N. Schartel"},{"name":"P. Serlemitsos"},{"name":"H. Seta"},{"name":"Y. Shibano"},{"name":"M. Shida"},{"name":"M. Shidatsu"},{"name":"T. Shimada"},{"name":"K. Shinozaki"},{"name":"P. Shirron"},{"name":"A. Simionescu"},{"name":"C. Simmons"},{"name":"Randall K. Smith"},{"name":"G. Sneiderman"},{"name":"Y. Soong"},{"name":"Ł. Stawarz"},{"name":"Y. Sugawara"},{"name":"H. Sugita"},{"name":"S. Sugita"},{"name":"A. Szymkowiak"},{"name":"H. Tajima"},{"name":"H. Takahashi"},{"name":"S. Takeda"},{"name":"Y. Takei"},{"name":"T. Tamagawa"},{"name":"T. Tamura"},{"name":"K. Tamura"},{"name":"Takaaki Tanaka"},{"name":"Yasuo Tanaka"},{"name":"Yasuyuki T. Tanaka"},{"name":"M. Tashiro"},{"name":"Y. Tawara"},{"name":"Y. Terada"},{"name":"Y. Terashima"},{"name":"F. Tombesi"},{"name":"H. Tomida"},{"name":"Y. Tsuboi"},{"name":"M. Tsujimoto"},{"name":"H. Tsunemi"},{"name":"T. Tsuru"},{"name":"H. Uchida"},{"name":"Yasunobu Uchiyama"},{"name":"H. Uchiyama"},{"name":"Y. Ueda"},{"name":"S. Ueda"},{"name":"S. Ueno"},{"name":"S. Uno"},{"name":"M. Urry"},{"name":"E. Ursino"},{"name":"C. D. de Vries"},{"name":"A. Wada"},{"name":"S. Watanabe"},{"name":"Tomomi Watanabe"},{"name":"N. Werner"},{"name":"D. Wik"},{"name":"D. Wilkins"},{"name":"B. Williams"},{"name":"Takahiro Yamada"},{"name":"S. Yamada"},{"name":"H. Yamaguchi"},{"name":"K. Yamaoka"},{"name":"N. Yamasaki"},{"name":"M. Yamauchi"},{"name":"S. Yamauchi"},{"name":"T. Yaqoob"},{"name":"Y. Yatsu"},{"name":"D. Yonetoku"},{"name":"A. Yoshida"},{"name":"T. Yuasa"},{"name":"I. Zhuravleva"},{"name":"A. Zoghbi"}],"abstract":"The Hitomi (ASTRO-H) mission is the sixth Japanese X-ray astronomy satellite developed by a large international collaboration, including Japan, USA, Canada, and Europe. The mission aimed to provide the highest energy resolution ever achieved at E \u003e 2 keV, using a microcalorimeter instrument, and to cover a wide energy range spanning four decades in energy from soft X-rays to gamma-rays. After a successful launch on 2016 February 17, the spacecraft lost its function on 2016 March 26, but the commissioning phase for about a month provided valuable information on the on-board instruments and the spacecraft system, including astrophysical results obtained from first light observations. The paper describes the Hitomi (ASTRO-H) mission, its capabilities, the initial operation, and the instruments/spacecraft performances confirmed during the commissioning operations for about a month.","source":"Semantic Scholar","year":2016,"language":"en","subjects":["Engineering","Physics"],"doi":"10.1117/12.2232379","url":"https://www.semanticscholar.org/paper/d876843e70c19c6e769cf64381b0e4153173360f","pdf_url":"https://dspace.mit.edu/bitstream/1721.1/116931/1/99050U.pdf","is_open_access":true,"citations":86,"published_at":"","score":62.58},{"id":"ss_29c30ccc4945a656e6c97f2be812454af399cc55","title":"Twisted Magnetic Field Emergence, Interchange Reconnection, Flux Cancellation, and Blow-Out Eruptions in a Small Coronal Hole","authors":[{"name":"M. Adams"},{"name":"N. Panesar"},{"name":"R. Moore"}],"abstract":"","source":"Semantic Scholar","year":2018,"language":"en","subjects":["Physics"],"url":"https://www.semanticscholar.org/paper/29c30ccc4945a656e6c97f2be812454af399cc55","is_open_access":true,"published_at":"","score":62},{"id":"ss_c466aeef5993c4a749d9ddcfdd7c26a5efacc154","title":"Precision Oncology and Genomically Guided Radiation Therapy, A Report From the ASTRO/AAPM/NCI Precision Medicine Conference","authors":[{"name":"W. Hall"},{"name":"C. Bergom"},{"name":"Reid F Thompson"},{"name":"A. Baschnagel"},{"name":"Srinivasan Vijayakumar"},{"name":"Henning"},{"name":"Willers"},{"name":"Allen X. Li"},{"name":"C. Schultz"},{"name":"G. Wilson"},{"name":"C. West"},{"name":"J. Capala"},{"name":"C. N. Coleman"},{"name":"F. Javier"},{"name":"Torres-Roca"},{"name":"J. Weidhaas"},{"name":"F. Feng"}],"abstract":"","source":"Semantic Scholar","year":2017,"language":"en","subjects":null,"doi":"10.1016/j.ijrobp.2017.05.044","url":"https://www.semanticscholar.org/paper/c466aeef5993c4a749d9ddcfdd7c26a5efacc154","is_open_access":true,"citations":25,"published_at":"","score":61.75},{"id":"ss_ccab5e096c052c9f8b01a336faf2ef38a503779a","title":"Pulsar Search Using Supervised Machine Learning","authors":[{"name":"J. Ford"}],"abstract":"","source":"Semantic Scholar","year":2017,"language":"en","subjects":["Computer Science","Physics"],"url":"https://www.semanticscholar.org/paper/ccab5e096c052c9f8b01a336faf2ef38a503779a","is_open_access":true,"citations":5,"published_at":"","score":61.15},{"id":"ss_b3add62ff279ccc6c874cd35726cc206bd55c2e9","title":"Circumstellar discs in Galactic centre clusters: Disc-bearing B-type stars in the Quintuplet and Arches clusters","authors":[{"name":"A. Stolte"},{"name":"B. Hussmann"},{"name":"C. Olczak"},{"name":"W. Brandner"},{"name":"M. Habibi"},{"name":"A. Ghez"},{"name":"M. Morris"},{"name":"Jessica R. Lu"},{"name":"W. Clarkson"},{"name":"Jay Anderson"}],"abstract":"Astronomy \u0026 Astrophysics manuscript no. discs_astro_11feb2014 February 13, 2015 c ESO Circumstellar discs in Galactic centre clusters: Disc-bearing B-type stars in the Quintuplet and Arches clusters ? A. Stolte 1 , B. Husmann 1 , C. Olczak 2 , W. Brandner 3 , M. Habibi 1 , A. M. Ghez 4, 5 , M. R. Morris 4 , J. R. Lu 6 , W. I. Clarkson 7 , J. Anderson 8 arXiv:1502.03681v1 [astro-ph.SR] 12 Feb 2015 Argelander Institut fur Astronomie, Universitat Bonn, Auf dem Hugel 71, 53121 Bonn, Germany Astronomisches Recheninstitut, Universitat Heidelberg, Monchhofstr. 12-14, 69120 Heidelberg, Germany Max-Planck-Institut fur Astronomie, Konigstuhl 17, 69117 Heidelberg, Germany Division of Astronomy and Astrophysics, UCLA, Los Angeles, CA 90095-1547, USA Institute of Geophysics and Planetary Physics, UCLA, Los Angeles, CA 90095, USA Institute for Astronomy, University of Hawai’i, 2680 Woodlawn Drive, Honolulu, HI 96822, USA Department of Natural Sciences, University of Michigan-Dearborn, 125 Science Building, 4901 Evergreen Road, Dearborn, MI 48128, USA Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218, USA February 13, 2015 ABSTRACT We investigate the circumstellar disc fraction as determined from L-band excess observations of the young, massive Arches and Quintuplet clusters residing in the central molecular zone of the Milky Way. The Quintuplet cluster was searched for L-band excess sources for the first time. We find a total of 26 excess sources in the Quintuplet cluster, and 21 sources with L-band excesses in the Arches cluster, of which 13 are new detections. With the aid of proper motion membership samples, the disc fraction of the Quintuplet cluster could be derived for the first time to be 4.0 ± 0.7%. There is no evidence for a radially varying disc fraction in this cluster. In the case of the Arches cluster, a disc fraction of 9.2 ± 1.2% approximately out to the cluster’s predicted tidal radius, r \u003c 1.5 pc, is observed. This excess fraction is consistent with our previously found disc fraction in the cluster in the radial range 0.3 \u003c r \u003c 0.8 pc. In both clusters, the host star mass range covers late A- to early B-type stars, 2 \u003c M \u003c 15 M , as derived from J-band photospheric magnitudes. We discuss the unexpected finding of dusty circumstellar discs in these UV intense environments in the context of primordial disc survival and formation scenarios of secondary discs. We consider the possibility that the L-band excess sources in the Arches and Quintuplet clusters could be the high-mass counterparts to T Tauri pre-transitional discs. As such a scenario requires a long pre-transitional disc lifetime in a UV intense environment, we suggest that mass transfer discs in binary systems are a likely formation mechanism for the B-star discs observed in these starburst clusters. Key words. open clusters and associations: individual (Quintuplet,Arches)–Galaxy: centre– stars: circumstellar matter–techniques: high angular resolution 1. Introduction In view of the short lifetimes of primordial circumstellar discs around B-type stars in dense environments, the detection of cir- cumstellar discs in the UV-rich environment of the Galactic cen- tre Arches cluster came as a surprise (Stolte et al. 2010). This detection raised the question of whether discs can also be found in the more evolved Quintuplet cluster, and whether these discs can have their origin in massive primordial discs sustained over the clusters’ lifetimes of several million years (Myr). In partic- ular, the nature of the disc sources in the Arches cluster has re- mained unsolved (see the discussion in Stolte et al. 2010). In the past five years, we have extended our disc search to larger radii in the Arches cluster and have encompassed the Quintu- plet cluster. With the aim of shedding light on the nature of the L-band excess sources found in both starburst clusters, we com- Based on data obtained at the ESO VLT under programme IDs 085.D-0446, 089.D-0121 (PI: Stolte), 081.D-0572 (PI: Brandner), 087.D-0720, 089.D-0430 (PI: Olzcak), 071.C-0344 (PI: Eisenhauer), 60.A-9026 (NAOS/CONICA science verification), as well as Hubble Space Telescope observations under programmes 11671 (PI:Ghez). pare their physical properties to pre-transitional discs and dis- cuss secondary mass transfer discs as a possible origin of the circumstellar material. 1.1. Circumstellar disc survival The survival of primordial circumstellar discs in young star clus- ters is known to be a steep function of cluster age (Haisch et al. 2001, Hernandez et al. 2005). For discs around low-mass stars, M ∼ 1 M , planet formation theories suggest that dust ag- glomeration causes a period of grain growth, while at the same time the dense gas of the primordial disc is evaporated by the central star (Cieza et al. 2012, Williams \u0026 Cieza 2011, Owen et al. 2011). In consequence, the thermal excess of evolved discs is dominated by increasingly longer wavelength emission, while the near-infrared contribution decreases and vanishes with time (e.g. Espaillat et al. 2012). The disc survival timescale in young stellar clusters is observed to be 3-10 Myr for intermediate-mass stars, 2 \u003c M \u003c 10 M (Hernandez et al. 2005), albeit with lower disc fractions at any given age as compared to clusters dominated by their lower-mass T Tauri counterparts (see Stolte Article number, page 1 of 47","source":"Semantic Scholar","year":2015,"language":"en","subjects":["Physics"],"doi":"10.1051/0004-6361/201424132","url":"https://www.semanticscholar.org/paper/b3add62ff279ccc6c874cd35726cc206bd55c2e9","pdf_url":"https://www.aanda.org/articles/aa/pdf/2015/06/aa24132-14.pdf","is_open_access":true,"citations":25,"published_at":"","score":59.75},{"id":"crossref_10.1093/ofid/ofv133.1240","title":"Development of Anemia and Changes in Hemoglobin Concentrations With Amphotericin B Therapy for Cryptococcal Meningitis","authors":[{"name":"Lillian Tugume"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Bozena Morawski"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Mahsa Abassi"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Nathan Bahr"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Reuben Kiggundu"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Henry Nabeta"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Kathy Huppler Hullsiek"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Taseera Kabanda"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Abdu Musubire"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Charlotte Schutz"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Conrad Muzoora"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Darlisha Williams"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Melissa Rolfes"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Graeme Meintjes"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"Joshua Rhein"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"David Meya"},{"name":"COAT Trial and ASTRO-CM Trial Teams"},{"name":"David Boulware"},{"name":"COAT Trial and ASTRO-CM Trial Teams"}],"abstract":"","source":"CrossRef","year":2015,"language":"en","subjects":null,"doi":"10.1093/ofid/ofv133.1240","url":"https://doi.org/10.1093/ofid/ofv133.1240","is_open_access":true,"published_at":"","score":59},{"id":"crossref_10.1093/ofid/ofv133.507","title":"Enhanced Consolidation Therapy With High-Dose Fluconazole and Sertraline Ameliorates Negative Outcomes Associated With Persistent Cerebrospinal Fluid Culture Positivity in Cryptococcal Meningitis","authors":[{"name":"Mahsa Abassi"},{"name":"on behalf of the ASTRO-CM Trial Team"},{"name":"Joshua Rhein"},{"name":"on behalf of the ASTRO-CM Trial Team"},{"name":"Bozena Morawski"},{"name":"on behalf of the ASTRO-CM Trial Team"},{"name":"Kathy H. Hullsiek"},{"name":"on behalf of the ASTRO-CM Trial Team"},{"name":"Lillian Tugume"},{"name":"on behalf of the ASTRO-CM Trial Team"},{"name":"Henry Nabeta"},{"name":"on behalf of the ASTRO-CM Trial Team"},{"name":"Reuben Kiggundu"},{"name":"on behalf of the ASTRO-CM Trial Team"},{"name":"Andrew Akampurira"},{"name":"on behalf of the ASTRO-CM Trial Team"},{"name":"Darlisha Williams"},{"name":"on behalf of the ASTRO-CM Trial Team"},{"name":"David Meya"},{"name":"on behalf of the ASTRO-CM Trial Team"},{"name":"David Boulware"},{"name":"on behalf of the ASTRO-CM Trial Team"}],"abstract":"","source":"CrossRef","year":2015,"language":"en","subjects":null,"doi":"10.1093/ofid/ofv133.507","url":"https://doi.org/10.1093/ofid/ofv133.507","is_open_access":true,"published_at":"","score":59},{"id":"crossref_10.1515/astro-2017-0362","title":"Mass Transfer in Mira-Type Binaries","authors":[{"name":"S. Mohamed"},{"name":"Ph. Podsiadlowski"}],"abstract":"AbstractDetached, symbiotic binaries are generally assumed to interact via Bondi-Hoyle-Littleton (BHL) wind accretion. However, the accretion rates and outflow geometries that result from this mass-transfer mechanism cannot adequately explain the observations of the nearest and best studied symbiotic binary, Mira, or the formation of some post-AGB binaries, e.g. barium stars. We propose a new mass-transfer mode for Mira-type binaries, which we call ‘wind Roche-lobe overflow’ (WRLOF), and which we demonstrate with 3D hydrodynamic simulations. Importantly, we show that the circumstellar outflows which result from WRLOF tend to be highly aspherical and strongly focused towards the binary orbital plane. Furthermore, the subsequent mass-transfer rates are at least an order of magnitude greater than the analogous BHL values. We discuss the implications of these results for the shaping of bipolar (proto)-planetary nebulae and other related systems.","source":"CrossRef","year":2012,"language":"en","subjects":null,"doi":"10.1515/astro-2017-0362","url":"https://doi.org/10.1515/astro-2017-0362","is_open_access":true,"citations":45,"published_at":"","score":57.35},{"id":"ss_0b447709d53c0a25d928ddd649e31251b1bfed15","title":"Comments on\"Experimental study of radiative shocks at PALS facility\"by Chantal Stehle et al. (arXiv:1003.2739v1 [astro-ph.SR])","authors":[{"name":"M. Busquet"}],"abstract":"Discussion on paper\"Experimental study of radiative shocks at PALS facility\"by C. Stehle et al (arXiv:1003.2739v1 [astro-ph.SR]) is presented, findings are questioned.","source":"Semantic Scholar","year":2012,"language":"en","subjects":["Physics"],"url":"https://www.semanticscholar.org/paper/0b447709d53c0a25d928ddd649e31251b1bfed15","is_open_access":true,"citations":1,"published_at":"","score":56.03}],"total":369476,"page":1,"page_size":20,"sources":["CrossRef","Semantic Scholar"],"query":"astro-ph.SR"}