{"results":[{"id":"ss_a94f9b3182c805d0fe8aa4239501042eaa1b286d","title":"Postpartum Depression: Pathophysiology, Treatment, and Emerging Therapeutics.","authors":[{"name":"D. Stewart"},{"name":"S. Vigod"}],"abstract":"Postpartum depression (PPD) is common, disabling, and treatable. The strongest risk factor is a history of mood or anxiety disorder, especially having active symptoms during pregnancy. As PPD is one of the most common complications of childbirth, it is vital to identify best treatments for optimal maternal, infant, and family outcomes. New understanding of PPD pathophysiology and emerging therapeutics offer the potential for new ways to add to current medications, somatic treatments, and evidence-based psychotherapy. The benefits and potential harms of treatment, including during breastfeeding, are presented.","source":"Semantic Scholar","year":2019,"language":"en","subjects":["Medicine"],"doi":"10.1146/annurev-med-041217-011106","url":"https://www.semanticscholar.org/paper/a94f9b3182c805d0fe8aa4239501042eaa1b286d","is_open_access":true,"citations":342,"published_at":"","score":73.26},{"id":"ss_81ed444db895d169f3614a1ce0ee21f3ccf5380a","title":"Psychedelic therapeutics in psychiatric conditions.","authors":[{"name":"Philip D. Harvey"},{"name":"Charles B. Nemeroff"}],"abstract":"","source":"Semantic Scholar","year":2026,"language":"en","subjects":["Medicine"],"doi":"10.1038/s41386-026-02335-z","url":"https://www.semanticscholar.org/paper/81ed444db895d169f3614a1ce0ee21f3ccf5380a","is_open_access":true,"citations":2,"published_at":"","score":70.06},{"id":"arxiv_2603.07963","title":"Designing a Generative AI-Assisted Music Psychotherapy Tool for Deaf and Hard-of-Hearing Individuals","authors":[{"name":"Youjin Choi"},{"name":"Jaeyoung Moon"},{"name":"Jinyoung Yoo"},{"name":"Jennifer G. Kim"},{"name":"Jin-Hyuk Hong"}],"abstract":"Songwriting has long served as a powerful medium for expressing unconscious emotions and fostering self-awareness in psychotherapy. Due to the auditory-centric nature of traditional approaches, Deaf and Hard-of-Hearing (DHH) individuals have often been excluded from music's therapeutic benefits. In response, this study presents a music psychotherapy tool co-designed with therapists, integrating conversational agents (CAs) and music generative AI as symbolic and therapeutic media. Through a usage study with 23 DHH individuals, we found that collaborative song writing with the CA enabled them to experience emotional release, reinterpretation, and deeper self-understanding. In particular, the CA's strategies -- supportive empathy, example response options, and visual-based metaphors -- were found to facilitate musical dialogue effectively for DHH individuals. These findings contribute to inclusive AI design by showing the potential of human-AI collaboration to bridge therapeutic artistic practices.","source":"arXiv","year":2026,"language":"en","subjects":["cs.HC"],"url":"https://arxiv.org/abs/2603.07963","pdf_url":"https://arxiv.org/pdf/2603.07963","is_open_access":true,"published_at":"2026-03-09T05:01:09Z","score":70},{"id":"arxiv_2602.12450","title":"Empirical Modeling of Therapist-Client Dynamics in Psychotherapy Using LLM-Based Assessments","authors":[{"name":"Angela Chen"},{"name":"Siwei Jin"},{"name":"Canwen Wang"},{"name":"Holly Swartz"},{"name":"Tongshuang Wu"},{"name":"Robert E Kraut"},{"name":"Haiyi Zhu"}],"abstract":"Psychotherapy is a primary treatment for many mental health conditions, yet the interplay among therapist behaviors, client responses, and the therapeutic relationship remains difficult to untangle. This work advances a computational approach for modeling these moment-to-moment processes. We first developed automated methods using large language models (LLMs) to assess therapist behaviors (e.g., empathy, exploration), relational qualities (e.g., rapport), and client outcomes (e.g., disclosure, self-directed and outward-directed negative emotions). These measures showed strong alignment with human ratings (mean Pearson $r = .66$). We then analyzed nearly 2,000 hours of psychotherapy transcripts from the Alexander Street corpus using Structural Equation Modeling (SEM). SEM showed that therapist empathy and exploration directly shaped client disclosure and emotional expression, whereas rapport may contribute to reductions in internal emotional distress rather than increased willingness to express it. Together, these findings demonstrate how computational tools can capture core therapeutic processes at scale and offer new opportunities for understanding, modeling, and improving therapist training.","source":"arXiv","year":2026,"language":"en","subjects":["cs.CY"],"url":"https://arxiv.org/abs/2602.12450","pdf_url":"https://arxiv.org/pdf/2602.12450","is_open_access":true,"published_at":"2026-02-12T22:14:07Z","score":70},{"id":"ss_37d51677e30d1aaad9bfd3163b082f18b1252927","title":"Comparison of the Effectiveness of Acupuncture Combined with Psychotherapy Versus Antidepressants in Treating Depression Among Adolescents: A Meta-Analysis Based on Chinese Literature","authors":[{"name":"Yufei Guo"},{"name":"Haihan Chen"},{"name":"W. Jin"}],"abstract":"Non-Suicidal Self-Injury (NSSI) refers to deliberate and repeated acts of damaging one's own body tissue without suicidal intent. It has have become a serious public health problem in the world. This study is to set a meta-analysis for exploring effectiveness of acupuncture combined with psychotherapy compared to antidepressant in treatment of adolescent depressive patients. Chinese and English literature related to treatment with combination of acupuncture and psychotherapy compared to antidepressant for adolescent patients with depression in China were searched. The comments, letters, reviews, and case reports were excluded. The index of depression, anxiety, and effectiveness in patients with was synthesized and discussed. A total of three studies were included, in which their studying type is acupuncture combined with psychotherapy compared to antidepressant in treatment of depressive patients. The lower score of anxiety and depression were found in combined acupuncture with psychotherapy compared to antidepressant in the end of treatment in adolescent depressive patients. It is found that higher rate of efficacy in combined acupuncture with psychotherapy compared to antidepressant in the end of treatment in adolescent depressive patients. The severity of anxiety and depression was significantly lower and higher effective rate in adolescent depressive patients with combination of acupuncture and psychotherapy than antidepressant after treatment. These results fully demonstrate the important role of complying with treatment guideline, in which non-pharmacotherapy was first choice.","source":"Semantic Scholar","year":2026,"language":"en","subjects":null,"doi":"10.1177/03601293251413786","url":"https://www.semanticscholar.org/paper/37d51677e30d1aaad9bfd3163b082f18b1252927","is_open_access":true,"published_at":"","score":70},{"id":"ss_cf8ac5929035b39bf33234fb1e55bdb1711504df","title":"Developing interactive VR-based digital therapeutics for Acceptance and Commitment Therapy (ACT): a structured framework for the digital transformation integrating gamification and multimodal arts","authors":[{"name":"Hyungsook Kim"},{"name":"Yoonyoung Choi"}],"abstract":"Introduction Digital therapeutics (DTx) require structured methodologies to translate evidence-based psychotherapy into immersive digital formats. In response to this need, this study proposes a practical framework for the digital transformation of Acceptance and Commitment Therapy (ACT) into an interactive virtual reality (VR) system. Methods DTx-ACT, designed as a therapeutic intervention for depression, is a VR-based system that delivers ACT through an immersive virtual experience. Its development followed five structured phases: preliminary research, design, development, advancement, and commercialization. The original ACT protocol was modularized into VR environments using the Session Structuring System (SSS) model. To enhance user engagement, gamification and multimodal arts strategies were incorporated. As part of the development process, evaluation metrics were defined to assess both clinical effectiveness and user interaction. Results The final system comprises five immersive VR sessions, each lasting 6 to 12 minutes. These modules incorporate ACT metaphors, interactive tasks, and multisensory feedback to enhance therapeutic engagement. To support the digital transformation of ACT, three core components were established: (1) an evidence-based therapeutic protocol, (2) interactive VR elements—including gamification and multimodal arts-based guidance, and (3) a data-driven evaluation framework. Evaluation metrics, derived from a pilot study, were integrated into the system, which collects clinical and interaction data—such as real-time behavioral patterns and sensor-based information—to enable comprehensive evaluation. Discussion Based on this development process, we propose a practical framework for designing interactive VR-based DTx. This framework bridges clinical structure, creative engagement, and real-time evaluation to support personalized and scalable applications in digital mental healthcare. It contributes to the standardization of digital transformation in evidence-based therapy and offers a transferable model for future therapeutic content development.","source":"Semantic Scholar","year":2025,"language":"en","subjects":["Medicine"],"doi":"10.3389/fpsyt.2025.1554394","url":"https://www.semanticscholar.org/paper/cf8ac5929035b39bf33234fb1e55bdb1711504df","is_open_access":true,"citations":4,"published_at":"","score":69.12},{"id":"doaj_10.22098/jrp.2025.16251.1272","title":"The effectiveness of an educational board game on the symptoms of attention deficit and hyperactivity disorder in children with ADHD","authors":[{"name":"ehsan golestani"},{"name":"Akbar Atadokht"},{"name":"Niloofar Mikaeili"},{"name":"Nader Hajloo"}],"abstract":"This study designed an educational board game and investigated its effectiveness on the symptoms of attention deficit and hyperactivity disorder (ADHD) in children. The population included 40 children aged seven to nine years in Baharestan County, Tehran Province in 2023 and selected by purposeful sampling and divided into two experimental and control groups randomly. The educational game was employed for 10 sessions in the experimental group. The instruments included the SNAP-IV questionnaire and diagnostic interview. Data was analyzed using repeated measures variance test in SPSS 23 software. The results showed that the educational board game had a significant effect on reducing children's hyperactivity symptoms and there was a significant difference between the experimental and control groups. Also, these effects remained stable in the follow-up phase.​​​​​​​​​ According to the findings, it can be generally concluded that game therapy, including physical games and cognitive games such as educational board games, can be used alongside first-line treatments as a complement or as an independent intervention for these children.","source":"DOAJ","year":2025,"language":"","subjects":["Therapeutics. Psychotherapy"],"doi":"10.22098/jrp.2025.16251.1272","url":"https://jrp.uma.ac.ir/article_4203_0fa945eb624f52712d3583d3a67dedad.pdf","pdf_url":"https://jrp.uma.ac.ir/article_4203_0fa945eb624f52712d3583d3a67dedad.pdf","is_open_access":true,"published_at":"","score":69},{"id":"doaj_10.51214/002025071583000","title":"Validity and Reliability of the Objective Measure of Ego Identity Status Adaptation: The Rasch Model Approach","authors":[{"name":"Nur Fadhilah Umar"},{"name":"M. Fiqri  Syahril"},{"name":"Salsabila Nasution"},{"name":"Nurfaidah Ardis"},{"name":"Humairah azzahrah"},{"name":"Muhammad  Rafli"}],"abstract":"\nEgo identity plays a crucial role in shaping an individual’s self-concept, career decisions, and social relationships. Accurately measuring ego identity status is essential for understanding identity formation and promoting healthy psychological development. This study examines the validity and reliability of the adapted Objective Measure of Ego Identity Status (OMEIS) using the Rasch Model, a contemporary psychometric approach that enhances measurement precision. A sample of 431 university students participated in this study, with data collected through an online questionnaire. Rasch analysis was employed to assess item fit, rating scale effectiveness, person reliability, and item difficulty levels. The results indicate that the adapted OMEIS demonstrates strong structural validity and high item reliability (0.99), although person reliability (0.63) requires improvement. The Wright Map analysis confirms the instrument’s ability to capture variations in ego identity, while item difficulty analysis highlights areas for potential refinement. Findings suggest that the Rasch Model provides a robust framework for validating psychological instruments, ensuring their applicability across diverse populations. This study contributes to the refinement of identity measurement tools and underscores the importance of advanced psychometric methodologies in psychological research\n","source":"DOAJ","year":2025,"language":"","subjects":["Therapeutics. Psychotherapy","Psychology"],"doi":"10.51214/002025071583000","url":"https://journal.kurasinstitute.com/index.php/bocp/article/view/1583","is_open_access":true,"published_at":"","score":69},{"id":"doaj_The+Tower+is+Falling%3A+Collapse%2C+Connection%2C+and+the+Possibility+of+Reorientation","title":"The Tower is Falling: Collapse, Connection, and the Possibility of Reorientation","authors":[{"name":"Hugh Palmer"}],"abstract":"\nThis paper uses the Tarot arc of the Devil, the Tower, the Star, and the Fool to explore systemic collapse and the logics of masculinised power. Drawing on archetypal imagery, ecological systems theory, posthumanist feminism, and lived experience, it argues that the panmorphic crisis (Simon, 2021) of climate change, technological acceleration, and political instability are not merely failures of implementation. They reflect a deeper failure of imagination. The Tower is falling because it was built on the ideology of the Devil, to deny relationship, vulnerability, and feedback.  In its place, the Star offers a different kind of intelligence: attentive, embodied, and quietly relational. Figures such as Trump and Musk are read not as aberrations but as expressions of a system that rewards shamelessness and disconnection. The paper invites readers into an ethic of reorientation, recognising even those we most oppose as part of our systemic kin. The Fool, traditionally male, is reclaimed as a post-binary, post-certainty figure who gestures toward a different way of going on, a journey that is uncertain, attentive, and deeply relational.\n","source":"DOAJ","year":2025,"language":"","subjects":["Therapeutics. Psychotherapy"],"url":"http://murmurations.cloud/index.php/pub/article/view/325","is_open_access":true,"published_at":"","score":69},{"id":"arxiv_2503.16521","title":"Conversational Self-Play for Discovering and Understanding Psychotherapy Approaches","authors":[{"name":"Onno P Kampman"},{"name":"Michael Xing"},{"name":"Charmaine Lim"},{"name":"Ahmad Ishqi Jabir"},{"name":"Ryan Louie"},{"name":"Jimmy Lee"},{"name":"Robert JT Morris"}],"abstract":"This paper explores conversational self-play with LLMs as a scalable approach for analyzing and exploring psychotherapy approaches, evaluating how well AI-generated therapeutic dialogues align with established modalities.","source":"arXiv","year":2025,"language":"en","subjects":["cs.HC","cs.MA"],"url":"https://arxiv.org/abs/2503.16521","pdf_url":"https://arxiv.org/pdf/2503.16521","is_open_access":true,"published_at":"2025-03-17T02:16:41Z","score":69},{"id":"arxiv_2502.11095","title":"A Survey of Large Language Models in Psychotherapy: Current Landscape and Future Directions","authors":[{"name":"Hongbin Na"},{"name":"Yining Hua"},{"name":"Zimu Wang"},{"name":"Tao Shen"},{"name":"Beibei Yu"},{"name":"Lilin Wang"},{"name":"Wei Wang"},{"name":"John Torous"},{"name":"Ling Chen"}],"abstract":"Mental health is increasingly critical in contemporary healthcare, with psychotherapy demanding dynamic, context-sensitive interactions that traditional NLP methods struggle to capture. Large Language Models (LLMs) offer significant potential for addressing this gap due to their ability to handle extensive context and multi-turn reasoning. This review introduces a conceptual taxonomy dividing psychotherapy into interconnected stages--assessment, diagnosis, and treatment--to systematically examine LLM advancements and challenges. Our comprehensive analysis reveals imbalances in current research, such as a focus on common disorders, linguistic biases, fragmented methods, and limited theoretical integration. We identify critical challenges including capturing dynamic symptom fluctuations, overcoming linguistic and cultural biases, and ensuring diagnostic reliability. Highlighting future directions, we advocate for continuous multi-stage modeling, real-time adaptive systems grounded in psychological theory, and diversified research covering broader mental disorders and therapeutic approaches, aiming toward more holistic and clinically integrated psychotherapy LLMs systems.","source":"arXiv","year":2025,"language":"en","subjects":["cs.CL"],"url":"https://arxiv.org/abs/2502.11095","pdf_url":"https://arxiv.org/pdf/2502.11095","is_open_access":true,"published_at":"2025-02-16T12:18:40Z","score":69},{"id":"arxiv_2504.16271","title":"The Language of Attachment: Modeling Attachment Dynamics in Psychotherapy","authors":[{"name":"Frederik Bredgaard"},{"name":"Martin Lund Trinhammer"},{"name":"Elisa Bassignana"}],"abstract":"The delivery of mental healthcare through psychotherapy stands to benefit immensely from developments within Natural Language Processing (NLP), in particular through the automatic identification of patient specific qualities, such as attachment style. Currently, the assessment of attachment style is performed manually using the Patient Attachment Coding System (PACS; Talia et al., 2017), which is complex, resource-consuming and requires extensive training. To enable wide and scalable adoption of attachment informed treatment and research, we propose the first exploratory analysis into automatically assessing patient attachment style from psychotherapy transcripts using NLP classification models. We further analyze the results and discuss the implications of using automated tools for this purpose -- e.g., confusing `preoccupied' patients with `avoidant' likely has a more negative impact on therapy outcomes with respect to other mislabeling. Our work opens an avenue of research enabling more personalized psychotherapy and more targeted research into the mechanisms of psychotherapy through advancements in NLP.","source":"arXiv","year":2025,"language":"en","subjects":["cs.CL"],"url":"https://arxiv.org/abs/2504.16271","pdf_url":"https://arxiv.org/pdf/2504.16271","is_open_access":true,"published_at":"2025-04-22T21:07:44Z","score":69},{"id":"arxiv_2509.02144","title":"A Theoretical Framework of the Processes of Change in Psychotherapy Delivered by Artificial Agents","authors":[{"name":"Arthur Bran Herbener"},{"name":"Malene Flensborg Damholdt"}],"abstract":"The question of whether artificial agents (e.g., chatbots and social robots) can replace human therapists has received notable attention following the recent launch of large language models. However, little is known about the processes of change in psychotherapy delivered by artificial agents. To facilitate hypothesis development and stimulate scientific debate, the present article offers the first theoretical framework of the processes of change in psychotherapy delivered by artificial agents. The theoretical framework rests upon a conceptual analysis of what active ingredients may be inherently linked to the presence of human therapists. We propose that human therapists' ontological status as human beings and sociocultural status as socially sanctioned healthcare professionals play crucial roles in promoting treatment outcomes. In the absence of the ontological and sociocultural status of human therapists, we propose what we coin the genuineness gap and credibility gap can emerge and undermine key processes of change in psychotherapy. Based on these propositions, we propose avenues for scientific investigations and practical applications aimed at leveraging the strengths of artificial agents and human therapists respectively. We also highlight the intricate agentic nature of artificial agents and discuss how this complicates endeavors to establish universally applicable propositions regarding the processes of change in these interventions.","source":"arXiv","year":2025,"language":"en","subjects":["cs.HC","cs.AI"],"url":"https://arxiv.org/abs/2509.02144","pdf_url":"https://arxiv.org/pdf/2509.02144","is_open_access":true,"published_at":"2025-09-02T09:45:40Z","score":69},{"id":"ss_90f32d6dd85c5132a204b931f0bf3a51cd4772c8","title":"ADVANCEMENTS IN MENTAL HEALTH: INTEGRATING AI WITH NATURAL PRODUCT-BASED THERAPEUTICS FOR ENHANCED DETECTION AND TREATMENT","authors":[{"name":"Dr. Thadiyan Parambil Ijinu"}],"abstract":"Mental health disorders are a significant global health challenge, affecting millions of individuals each year and often resulting in long-term disability, impaired quality of life, and considerable societal burden. Conditions such as depression, anxiety, bipolar disorder, schizophrenia, and other psychiatric illnesses have traditionally been diagnosed and treated using clinical assessments, psychotherapy, and pharmaceutical interventions. However, despite ongoing advancements in mental health treatment, existing methods often fall short in terms of early detection, personalized care, and long-term effectiveness. In recent years, the integration of artificial intelligence (AI) with natural product-based therapeutics has emerged as a promising and innovative solution for addressing these gaps in mental health care. AI, with its ability to analyze large datasets, recognize complex patterns, and provide predictive insights, holds great potential in enhancing the early diagnosis, personalized treatment, and continuous monitoring of mental health conditions. Meanwhile, natural products, including herbs, plant-based compounds, and nutraceuticals, offer time-tested therapeutic benefits that are increasingly being recognized and studied within modern psychiatric care. AI-powered tools can offer precise, individualized predictions of mental health conditions by analyzing patient data, including genetic markers, behavior patterns, environmental factors, and treatment responses. These technologies enable the identification of early warning signs and more accurate diagnoses, which are crucial for initiating effective interventions at an earlier stage, ultimately improving patient outcomes. Moreover, AI can optimize treatment plans by tailoring them to each patient's unique biology, ensuring the right combination of therapies, whether pharmaceutical or natural, based on real-time feedback and monitoring. On the other hand, natural product-based therapeutics, with their rich history in traditional medicine and growing body of scientific evidence, present a natural complement to AI-based approaches. Herbs, adaptogens, and nutraceuticals have been shown to have mood-regulating, anti-anxiety, and neuroprotective properties that may help alleviate symptoms of mental health disorders. When integrated with AI systems, these natural products can be used in a more personalized, targeted manner, enhancing their therapeutic effectiveness and minimizing potential side effects. The potential benefits of combining AI and natural therapeutics in mental health care are Early Diagnosis, Personalized Treatment AND Continuous Monitoring and Optimization. This white paper aims to provide an in-depth exploration of the current state of mental health disorder detection and treatment, outline the role of AI in improving diagnosis and therapeutic outcomes, and highlight the potential for integrating AI with natural product-based treatments. By addressing the challenges and exploring the opportunities, this paper envisions a future where AI and natural therapeutics work in synergy to provide more effective, personalized, and accessible mental health care.","source":"Semantic Scholar","year":2025,"language":"en","subjects":null,"doi":"10.26483/ijarcs.v16i3.7282","url":"https://www.semanticscholar.org/paper/90f32d6dd85c5132a204b931f0bf3a51cd4772c8","is_open_access":true,"published_at":"","score":69},{"id":"ss_6f72c26aea4562d719caf54919c942109c2c40cd","title":"The Effects of an Accelerated Experiential Dynamic Psychotherapy based Group Figure Therapy Program on Self-Awareness and Self-Acceptance in Preparatory Play Therapists with Insecure Adult Attachment","authors":[{"name":"B. Shin"},{"name":"Nam-sook Roh"}],"abstract":"This study aimed to verify the effects of an AEDP based Group Figure Therapy Program on self-awareness and self-acceptance in preparatory play therapists with insecure adult attachment. The study involved 20 students from the Department of Child Psychotherapy at the Graduate School of Integrative Therapeutics, University of M. comprising an experimental group of 10 and a restricted group of 10. To measure the program’s impact, self-awareness and self-acceptance scales were administered as pre- and post-tests, with results analyzed using the Wilcoxon non-parametric statistical test method. Additionally, qualitative data-including video recordings, photographs, and verbatim transcripts of the sessions-were analyzed. The findings indicated a significant increase in self-awareness and self-acceptance scores among participants in the experimental group compared to their pre-test scores. That is, the program proved effective in enhancing self-awareness and self-acceptance among preparatory play therapists with insecure adult attachment.","source":"Semantic Scholar","year":2025,"language":"en","subjects":null,"doi":"10.23909/kjcc.2025.8.36.3.103.","url":"https://www.semanticscholar.org/paper/6f72c26aea4562d719caf54919c942109c2c40cd","is_open_access":true,"published_at":"","score":69},{"id":"ss_a5eed83a3d08fd153cd904a258ab621bbbc8a767","title":"Benefits of a 12-week psychotherapy course for people with Parkinson’s disease: a service improvement project","authors":[{"name":"A. Roussakis"},{"name":"Rima Hawkins"},{"name":"Cara Mackley"},{"name":"Paola Piccini"}],"abstract":"The psychological symptoms of Parkinson’s disease (PD) worsen the quality of life of patients and their partners. However, these non-motor symptoms (mainly anxiety and depression) remain undiagnosed and undertreated in PD. Here, we report the benefits of a 12-week intervention using talking therapy (psychotherapy and counselling). This work was conducted in a group of individuals (people living with PD, and partners) with mild-to-moderate anxiety and depression. We discuss our results in context and conclude that short-term talking therapy should be integrated into PD therapeutics.","source":"Semantic Scholar","year":2025,"language":"en","subjects":["Medicine"],"doi":"10.1007/s00415-024-12867-3","url":"https://www.semanticscholar.org/paper/a5eed83a3d08fd153cd904a258ab621bbbc8a767","pdf_url":"https://doi.org/10.1007/s00415-024-12867-3","is_open_access":true,"published_at":"","score":69},{"id":"ss_da6cc5cf6ca7006297df009b066f976ff13210f2","title":"The evolution of psychotherapy: from Freud to prescription digital therapeutics","authors":[{"name":"J. P. Docherty"},{"name":"Brett M. Colbert"}],"abstract":"The evolution of psychotherapeutic treatments from Freud to digitally administered evidence-based treatments reflects a history of progressive advance. This history is characterized by identification of problems with the current state of the art, followed by solutions inspired and supported by advances in basic science and technology leading to subsequent recognition of other limitations revealed by the new advance. The common thread running through this process is (a) increasing specificity of the psychotherapeutic interventions, (b) increasing evidence of efficacy and safety, (c) increasing integrity and reliability in the delivery of the intervention, (d) increased equality of access, and (e) recognition of the need for regulation to provide protection for the public from unsafe or ineffective products. This evolution of psychotherapeutic treatments, not surprisingly, has been foreshadowed by the precursor history of the evolution of pharmacologic treatment. Although intellectual history is lumpy and does not sort itself into discrete and coherent epochs, such sorting is a useful heuristic for describing the advance of medicine and the therapeutic enterprise. This paper will discuss six successive epochs of psychotherapy. For each it will discuss the problem of the preceding era it sought to solve, the advance it brought to the field, the emerging science and technology that supported that advance, and the precursor development in pharmacological treatments that foreshadowed that epoch of psychotherapy. Finally, it will conclude with some observations about the proximate future.","source":"Semantic Scholar","year":2024,"language":"en","subjects":["Medicine"],"doi":"10.3389/fpsyt.2024.1477543","url":"https://www.semanticscholar.org/paper/da6cc5cf6ca7006297df009b066f976ff13210f2","is_open_access":true,"citations":6,"published_at":"","score":68.18},{"id":"ss_93f6cb08da90bda6b0668bcf6e6a6478e86e900d","title":"Chronic Pain for Rheumatological Disorders: Pathophysiology, Therapeutics and Evidence.","authors":[{"name":"Yian Chen"},{"name":"Ariana M. Nelson"},{"name":"S. P. Cohen"}],"abstract":"Pain is the leading reason people seek orthopedic and rheumatological care. By definition, most pain can be classified as nociceptive, or pain resulting from non-neural tissue injury or potential injury, with between 15% and 50% of individuals suffering from concomitant neuropathic pain or the newest category of pain, nociplastic pain, defined as \"pain arising from altered nociception despite no clear evidence of actual or threatened tissue damage, or of a disease or lesion affecting the somatosensory system.‿ Pain classification is important because it affects treatment decisions at all levels of care. Although several instruments can assist with classifying treatment, physician designation is the reference standard. The appropriate treatment of pain should ideally involve multidisciplinary care including physical therapy, psychotherapy and integrative therapies when appropriate, and pharmacotherapy with non-steroidal anti-inflammatory drugs for acute, mechanical pain, membrane stabilizers for neuropathic and nociplastic pain, and serotonin-norepinephrine reuptake inhibitors and tricyclic antidepressants for all types of pain. For non-surgical interventions, there is evidence to support a small effect for epidural steroid injections for an intermediate-term duration, and conflicting evidence for radiofrequency ablation to provide at least 6 months of benefit for facet joint pain, knee osteoarthritis, and sacroiliac joint pain. Since pain and disability represent the top reason for elective surgery, it should be reserved for patients who fail conservative interventions. Risk factors for procedural failure are the same as risk factors for conservative treatment failure and include greater disease burden, psychopathology, opioid use, central sensitization and multiple co-morbid pain conditions, poorly controlled preoperative and postoperative pain, and secondary gain.","source":"Semantic Scholar","year":2024,"language":"en","subjects":["Medicine"],"doi":"10.1016/j.jbspin.2024.105750","url":"https://www.semanticscholar.org/paper/93f6cb08da90bda6b0668bcf6e6a6478e86e900d","is_open_access":true,"citations":3,"published_at":"","score":68.09},{"id":"crossref_10.1016/b978-0-443-18496-3.00001-x","title":"Interventional therapeutics in psychiatry: Beyond psychopharmacology and psychotherapy?","authors":[{"name":"Frank Padberg"},{"name":"Gerrit Burkhardt"}],"abstract":"","source":"CrossRef","year":2024,"language":"en","subjects":null,"doi":"10.1016/b978-0-443-18496-3.00001-x","url":"https://doi.org/10.1016/b978-0-443-18496-3.00001-x","is_open_access":true,"published_at":"","score":68}],"total":760111,"page":1,"page_size":20,"sources":["CrossRef","DOAJ","arXiv","Semantic Scholar"],"query":"Therapeutics. Psychotherapy"}