Retrospective study
Abstrak
AbstractConventional forceps biopsy (CFB) is the most popular way to screen for gastric epithelial neoplasia (GEN) and adenocarcinoma of gastric epithelium. The aim of this study was to compare the diagnostic accuracy between conventional forceps biopsy and endoscopic submucosal dissection (ESD).Four hundred forty-four patients who finally undertook ESD in our hospital were enrolled from Jan 1, 2009 to Sep 1, 2015. We retrospectively assessed the characteristics of pathological results of CFB and ESD.The concordance rate between CFB and ESD specimens was 68.92% (306/444). Men showed a lower concordance rate (63.61% vs 79.33%; P = 0.001) and concordance patients were younger (P = 0.048). In multivariate analysis, men significantly had a lower concordance rate (coefficient −0.730, P = 0.002) and a higher rate of pathological upgrade (coefficient −0.648, P = 0.015). Locations of CFB did not influence the concordance rate statistically.The concordance rate was relatively high in our hospital. According to our analysis, old men plus gastric fundus or antrum of CFB were strongly suggested to perform ESD if precancerous lesions were found. And young women with low-grade intraepithelial neoplasia could select regular follow-up.
Topik & Kata Kunci
Penulis (8)
Chao Lu
Xueyou Lv
Yiming Lin
Dejian Li
Lihua Chen
Feng Ji
Youming Li
Chaohui Yu
Akses Cepat
- Tahun Terbit
- 2016
- Bahasa
- en
- Total Sitasi
- 4449×
- Sumber Database
- Semantic Scholar
- DOI
- 10.1097/MD.0000000000004353
- Akses
- Open Access ✓