Semantic Scholar Open Access 2018 1662 sitasi

Protein Phase Separation: A New Phase in Cell Biology.

S. Boeynaems S. Alberti N. Fawzi Tanja Mittag M. Polymenidou +7 lainnya

Lihat Sumber DOI

Abstrak

Cellular compartments and organelles organize biological matter. Most well-known organelles are separated by a membrane boundary from their surrounding milieu. There are also many so-called membraneless organelles and recent studies suggest that these organelles, which are supramolecular assemblies of proteins and RNA molecules, form via protein phase separation. Recent discoveries have shed light on the molecular properties, formation, regulation, and function of membraneless organelles. A combination of techniques from cell biology, biophysics, physical chemistry, structural biology, and bioinformatics are starting to help establish the molecular principles of an emerging field, thus paving the way for exciting discoveries, including novel therapeutic approaches for the treatment of age-related disorders.

Topik & Kata Kunci

Biology Medicine

Penulis (12)

S. Boeynaems

S. Alberti

N. Fawzi

Tanja Mittag

M. Polymenidou

F. Rousseau

J. Schymkowitz

J. Shorter

B. Wolozin

L. Van Den Bosch

P. Tompa

M. Fuxreiter

Format Sitasi

APA MLA BibTeX

Boeynaems, S., Alberti, S., Fawzi, N., Mittag, T., Polymenidou, M., Rousseau, F. et al. (2018). Protein Phase Separation: A New Phase in Cell Biology.. https://doi.org/10.1016/j.tcb.2018.02.004

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.tcb.2018.02.004

Informasi Jurnal

Tahun Terbit: 2018
Bahasa: en
Total Sitasi: 1662×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.tcb.2018.02.004
Akses: Open Access ✓