Semantic Scholar Open Access 2018 167 sitasi

Dynamic Human Environmental Exposome Revealed by Longitudinal Personal Monitoring.

Chao Jiang Xin Wang Xiyan Li Jingga Inlora Tingli Wang +2 lainnya

Lihat Sumber DOI

Abstrak

Human health is dependent upon environmental exposures, yet the diversity and variation in exposures are poorly understood. We developed a sensitive method to monitor personal airborne biological and chemical exposures and followed the personal exposomes of 15 individuals for up to 890 days and over 66 distinct geographical locations. We found that individuals are potentially exposed to thousands of pan-domain species and chemical compounds, including insecticides and carcinogens. Personal biological and chemical exposomes are highly dynamic and vary spatiotemporally, even for individuals located in the same general geographical region. Integrated analysis of biological and chemical exposomes revealed strong location-dependent relationships. Finally, construction of an exposome interaction network demonstrated the presence of distinct yet interconnected human- and environment-centric clouds, comprised of interacting ecosystems such as human, flora, pets, and arthropods. Overall, we demonstrate that human exposomes are diverse, dynamic, spatiotemporally-driven interaction networks with the potential to impact human health.

Topik & Kata Kunci

Biology Medicine

Penulis (7)

Chao Jiang

Xin Wang

Xiyan Li

Jingga Inlora

Tingli Wang

Qing Liu

Michael Snyder

Format Sitasi

APA MLA BibTeX

Jiang, C., Wang, X., Li, X., Inlora, J., Wang, T., Liu, Q. et al. (2018). Dynamic Human Environmental Exposome Revealed by Longitudinal Personal Monitoring.. https://doi.org/10.1016/j.cell.2018.08.060

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.cell.2018.08.060

Informasi Jurnal

Tahun Terbit: 2018
Bahasa: en
Total Sitasi: 167×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.cell.2018.08.060
Akses: Open Access ✓