Semantic Scholar Open Access 2017 413 sitasi

THPdb: Database of FDA-approved peptide and protein therapeutics

S. Usmani Gursimran Bedi Jesse S. Samuel Sandeep Singh Sourav Kalra +5 lainnya

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Abstrak

THPdb (http://crdd.osdd.net/raghava/thpdb/) is a manually curated repository of Food and Drug Administration (FDA) approved therapeutic peptides and proteins. The information in THPdb has been compiled from 985 research publications, 70 patents and other resources like DrugBank. The current version of the database holds a total of 852 entries, providing comprehensive information on 239 US-FDA approved therapeutic peptides and proteins and their 380 drug variants. The information on each peptide and protein includes their sequences, chemical properties, composition, disease area, mode of activity, physical appearance, category or pharmacological class, pharmacodynamics, route of administration, toxicity, target of activity, etc. In addition, we have annotated the structure of most of the protein and peptides. A number of user-friendly tools have been integrated to facilitate easy browsing and data analysis. To assist scientific community, a web interface and mobile App have also been developed.

Topik & Kata Kunci

Medicine

Penulis (10)

S. Usmani

Gursimran Bedi

Jesse S. Samuel

Sandeep Singh

Sourav Kalra

Pawan Kumar

A. Ahuja

Meenu Sharma

A. Gautam

G. Raghava

Format Sitasi

APA MLA BibTeX

Usmani, S., Bedi, G., Samuel, J.S., Singh, S., Kalra, S., Kumar, P. et al. (2017). THPdb: Database of FDA-approved peptide and protein therapeutics. https://doi.org/10.1371/journal.pone.0181748

Akses Cepat

Lihat di Sumber doi.org/10.1371/journal.pone.0181748

Informasi Jurnal

Tahun Terbit: 2017
Bahasa: en
Total Sitasi: 413×
Sumber Database: Semantic Scholar
DOI: 10.1371/journal.pone.0181748
Akses: Open Access ✓