Semantic Scholar
Open Access
2013
542 sitasi
Basic Concepts in Physiologically Based Pharmacokinetic Modeling in Drug Discovery and Development
Hm Jones
K. Rowland-Yeo
Abstrak
The aim of this tutorial is to introduce the concept of physiologically based pharmacokinetic (PBPK) modeling to individuals in the pharmaceutical industry who may be relatively new to this area and to demonstrate application of this approach in a preclinical and clinical setting. The tutorial provides some background on PBPK models and their data requirements, introduces strategies for PBPK modeling in drug development, and includes a discussion on regulatory considerations and potential resource issues.
Topik & Kata Kunci
Penulis (2)
H
Hm Jones
K
K. Rowland-Yeo
Akses Cepat
Informasi Jurnal
- Tahun Terbit
- 2013
- Bahasa
- en
- Total Sitasi
- 542×
- Sumber Database
- Semantic Scholar
- DOI
- 10.1038/psp.2013.41
- Akses
- Open Access ✓