Semantic Scholar Open Access 2017 383 sitasi

The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease.

K. Cooke L. Luznik S. Sarantopoulos F. Hakim M. Jagasia +12 lainnya

Abstrak

Chronic graft-versus-host disease (GVHD) is the leading cause of late, nonrelapse mortality and disability in allogeneic hematopoietic cell transplantation recipients and a major obstacle to improving outcomes. The biology of chronic GVHD remains enigmatic, but understanding the underpinnings of the immunologic mechanisms responsible for the initiation and progression of disease is fundamental to developing effective prevention and treatment strategies. The goals of this task force review are as follows: This document is intended as a review of our understanding of chronic GVHD biology and therapies resulting from preclinical studies, and as a platform for developing innovative clinical strategies to prevent and treat chronic GVHD.

Topik & Kata Kunci

Penulis (17)

K

K. Cooke

L

L. Luznik

S

S. Sarantopoulos

F

F. Hakim

M

M. Jagasia

D

D. Fowler

M

M. V. D. van den Brink

J

J. Hansen

R

R. Parkman

D

D. Miklos

P

P. Martin

S

S. Paczesny

G

G. Vogelsang

S

S. Pavletic

J

J. Ritz

K

K. Schultz

B

B. Blazar

Format Sitasi

Cooke, K., Luznik, L., Sarantopoulos, S., Hakim, F., Jagasia, M., Fowler, D. et al. (2017). The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease.. https://doi.org/10.1016/j.bbmt.2016.09.023

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.bbmt.2016.09.023
Informasi Jurnal
Tahun Terbit
2017
Bahasa
en
Total Sitasi
383×
Sumber Database
Semantic Scholar
DOI
10.1016/j.bbmt.2016.09.023
Akses
Open Access ✓