Semantic Scholar Open Access 2016 2741 sitasi

Fast gene set enrichment analysis

Gennady Korotkevich V. Sukhov A. Sergushichev

Lihat Sumber DOI

Abstrak

Preranked gene set enrichment analysis (GSEA) is a widely used method for interpretation of gene expression data in terms of biological processes. Here we present FGSEA method that is able to estimate arbitrarily low GSEA P-values with a higher accuracy and much faster compared to other implementations. We also present a polynomial algorithm to calculate GSEA P-values exactly, which we use to practically confirm the accuracy of the method.

Topik & Kata Kunci

Biology Computer Science

Penulis (3)

Gennady Korotkevich

V. Sukhov

A. Sergushichev

Format Sitasi

APA MLA BibTeX

Korotkevich, G., Sukhov, V., Sergushichev, A. (2016). Fast gene set enrichment analysis. https://doi.org/10.1101/060012

Akses Cepat

Lihat di Sumber doi.org/10.1101/060012

Informasi Jurnal

Tahun Terbit: 2016
Bahasa: en
Total Sitasi: 2741×
Sumber Database: Semantic Scholar
DOI: 10.1101/060012
Akses: Open Access ✓