Semantic Scholar Open Access 2018 293 sitasi

The recent progress of isoxazole in medicinal chemistry.

Jie Zhu J. Mo Hongzhi Lin Yao Chen Haopeng Sun

Abstrak

Isoxazole compounds exhibit a wide spectrum of targets and broad biological activities. Developing compounds with heterocycle rings has been one of the trends. The integration of isoxazole ring can offer improved physical-chemical properties. Because of the unique profiles, isoxazole ring becomes a popular moiety in compounds design. In this review article, the major focus has been paid to the applications of isoxazole compounds in treating multiple diseases, including anticancer, antimicrobial, anti-inflammatory, etc. Strategies for compounds design for preclinical, clinical, and FDA approved drugs were discussed. Also, the emphasis has been addressed to the future perspectives and trend for the application.

Topik & Kata Kunci

Medicine Chemistry

Penulis (5)

Jie Zhu

J. Mo

Hongzhi Lin

Yao Chen

Haopeng Sun

Format Sitasi

APA MLA BibTeX

Zhu, J., Mo, J., Lin, H., Chen, Y., Sun, H. (2018). The recent progress of isoxazole in medicinal chemistry.. https://doi.org/10.1016/j.bmc.2018.05.013

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Informasi Jurnal

Tahun Terbit: 2018
Bahasa: en
Total Sitasi: 293×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.bmc.2018.05.013
Akses: Open Access ✓