Semantic Scholar Open Access 2024 10 sitasi

A Novel Benzothiazole-Based Fluorescent AIE Probe for the Detection of Hydrogen Peroxide in Living Cells

Dezhi Shi Yulong Yang Luan Tong Likang Zhang Fengqing Yang +2 lainnya

Lihat Sumber DOI

Abstrak

A benzothiazole-based derivative aggregation-induced emission (AIE) fluorescent ‘turn-on’ probe named 2-(2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)phenyl)benzo[d]thiazole (probe BT-BO) was developed and synthesized successfully for detecting hydrogen peroxide (H2O2) in living cells. The synthesis method of probe BT-BO is facile. Probe BT-BO demonstrates a well-resolved emission peak at 604 nm and the ability to prevent the interference of reactive oxygen species (ROS), various metal ions and anion ions, and good sensitivity. Additionally, the probe boasts impressive pH range versatility, a fast response time to H2O2 and low cytotoxicity. Finally, probe BT-BO was applied successfully to image A549 and Hep G2 cells to monitor both exogenous and endogenous H2O2.

Topik & Kata Kunci

Medicine

Penulis (7)

Dezhi Shi

Yulong Yang

Luan Tong

Likang Zhang

Fengqing Yang

Jiali Tao

Mingxia Zhao

Format Sitasi

APA MLA BibTeX

Shi, D., Yang, Y., Tong, L., Zhang, L., Yang, F., Tao, J. et al. (2024). A Novel Benzothiazole-Based Fluorescent AIE Probe for the Detection of Hydrogen Peroxide in Living Cells. https://doi.org/10.3390/molecules29215181

Akses Cepat

Lihat di Sumber doi.org/10.3390/molecules29215181

Informasi Jurnal

Tahun Terbit: 2024
Bahasa: en
Total Sitasi: 10×
Sumber Database: Semantic Scholar
DOI: 10.3390/molecules29215181
Akses: Open Access ✓