Semantic Scholar Open Access 2019 518 sitasi

The role of interleukin-1 in general pathology

Naoe Kaneko M. Kurata Toshihiro Yamamoto Shinnosuke Morikawa J. Masumoto

Lihat Sumber DOI

Abstrak

Interleukin-1, an inflammatory cytokine, is considered to have diverse physiological functions and pathological significances and play an important role in health and disease. In this decade, interleukin-1 family members have been expanding and evidence is accumulating that highlights the importance of interleukin-1 in linking innate immunity with a broad spectrum of diseases beyond inflammatory diseases. In this review, we look back on the definition of “inflammation” in traditional general pathology and discuss new insights into interleukin-1 in view of its history and the molecular bases of diseases, as well as current progress in therapeutics.

Topik & Kata Kunci

Medicine

Penulis (5)

Naoe Kaneko

M. Kurata

Toshihiro Yamamoto

Shinnosuke Morikawa

J. Masumoto

Format Sitasi

APA MLA BibTeX

Kaneko, N., Kurata, M., Yamamoto, T., Morikawa, S., Masumoto, J. (2019). The role of interleukin-1 in general pathology. https://doi.org/10.1186/s41232-019-0101-5

Akses Cepat

Lihat di Sumber doi.org/10.1186/s41232-019-0101-5

Informasi Jurnal

Tahun Terbit: 2019
Bahasa: en
Total Sitasi: 518×
Sumber Database: Semantic Scholar
DOI: 10.1186/s41232-019-0101-5
Akses: Open Access ✓