Semantic Scholar Open Access 2020 1288 sitasi

Pulmonary Pathology of Early-Phase 2019 Novel Coronavirus (COVID-19) Pneumonia in Two Patients With Lung Cancer

S. Tian Weidong Hu L. Niu Huan Liu Haibo Xu +1 lainnya

Lihat Sumber DOI

Abstrak

There is currently a lack of pathologic data on the novel coronavirus (severe acute respiratory syndrome coronavirus 2) pneumonia, or coronavirus disease 2019 (COVID-19), from autopsy or biopsy. Two patients who recently underwent lung lobectomies for adenocarcinoma were retrospectively found to have had COVID-19 at the time of the operation. These two cases thus provide important first opportunities to study the pathology of COVID-19. Pathologic examinations revealed that apart from the tumors, the lungs of both patients exhibited edema, proteinaceous exudate, focal reactive hyperplasia of pneumocytes with patchy inflammatory cellular infiltration, and multinucleated giant cells. Hyaline membranes were not prominent. Because both patients did not exhibit symptoms of pneumonia at the time of operation, these changes likely represent an early phase of the lung pathology of COVID-19 pneumonia.

Topik & Kata Kunci

Medicine

Penulis (6)

S. Tian

Weidong Hu

L. Niu

Huan Liu

Haibo Xu

S. Xiao

Format Sitasi

APA MLA BibTeX

Tian, S., Hu, W., Niu, L., Liu, H., Xu, H., Xiao, S. (2020). Pulmonary Pathology of Early-Phase 2019 Novel Coronavirus (COVID-19) Pneumonia in Two Patients With Lung Cancer. https://doi.org/10.1016/j.jtho.2020.02.010

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.jtho.2020.02.010

Informasi Jurnal

Tahun Terbit: 2020
Bahasa: en
Total Sitasi: 1288×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.jtho.2020.02.010
Akses: Open Access ✓