Semantic Scholar Open Access 1996 154 sitasi

Criterion that determines the foldability of proteins.

D. Klimov D. Thirumalai

Abstrak

We point out that the correlation between folding times and $\sigma = (T_{\theta } - T_{f})/T_{\theta }$ in protein-like heteropolymer models where $T_{\theta }$ and $T_{f}$ are the collapse and folding transition temperatures was already established in 1993 before the other presumed equivalent criterion (folding times correlating with $T_{f}$ alone) was suggested. We argue that the folding times for these models show no useful correlation with the energy gap even if restricted to the ensemble of compact structures as suggested by Karplus and Shakhnovich (cond-mat/9606037).

Penulis (2)

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D. Klimov

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D. Thirumalai

Format Sitasi

Klimov, D., Thirumalai, D. (1996). Criterion that determines the foldability of proteins.. https://doi.org/10.1103/PhysRevLett.76.4070

Akses Cepat

Lihat di Sumber doi.org/10.1103/PhysRevLett.76.4070
Informasi Jurnal
Tahun Terbit
1996
Bahasa
en
Total Sitasi
154×
Sumber Database
Semantic Scholar
DOI
10.1103/PhysRevLett.76.4070
Akses
Open Access ✓