Semantic Scholar Open Access 2006 2647 sitasi

Glycosylation in cellular mechanisms of health and disease.

K. Ohtsubo J. Marth

Lihat Sumber DOI

Abstrak

Glycosylation produces an abundant, diverse, and highly regulated repertoire of cellular glycans that are frequently attached to proteins and lipids. The past decade of research on glycan function has revealed that the enzymes responsible for glycosylation-the glycosyltransferases and glycosidases-are essential in the development and physiology of living organisms. Glycans participate in many key biological processes including cell adhesion, molecular trafficking and clearance, receptor activation, signal transduction, and endocytosis. This review discusses the increasingly sophisticated molecular mechanisms being discovered by which mammalian glycosylation governs physiology and contributes to disease.

Topik & Kata Kunci

Medicine Biology

Penulis (2)

K. Ohtsubo

J. Marth

Format Sitasi

APA MLA BibTeX

Ohtsubo, K., Marth, J. (2006). Glycosylation in cellular mechanisms of health and disease.. https://doi.org/10.1016/J.CELL.2006.08.019

Akses Cepat

Lihat di Sumber doi.org/10.1016/J.CELL.2006.08.019

Informasi Jurnal

Tahun Terbit: 2006
Bahasa: en
Total Sitasi: 2647×
Sumber Database: Semantic Scholar
DOI: 10.1016/J.CELL.2006.08.019
Akses: Open Access ✓