Semantic Scholar Open Access 2017 298 sitasi

Role of reactive oxygen species in male infertility: An updated review of literature

H. Wagner Julie W. Cheng Edmund Y Ko

Lihat Sumber DOI

Abstrak

Abstract Objectives To review the literature and provide an updated summary on the role of reactive oxygen species (ROS) in male infertility. Methods A review of PubMed, Cochrane review, and Web of Science databases for full-text English-language articles published between 1943 and 2017 was performed, focusing on the aetiology of ROS, physiological role of ROS on spermatic function, pathological role of ROS in infertility, evaluation of ROS, and role of antioxidants in oxidative stress. Results ROS play a role in spermatic function and fertilisation. The literature describes both a physiological and a pathological role of ROS in fertility. A delicate balance between ROS necessary for physiological activity and antioxidants to protect from cellular oxidative injury is essential for fertility. Conclusion Although elevated levels of ROS are implicated as a cause of infertility, there is no consensus on selecting patients to test for ROS, which test to perform, or if treatment for ROS can have a positive impact on infertility rates and pregnancy.

Topik & Kata Kunci

Medicine

Penulis (3)

H. Wagner

Julie W. Cheng

Edmund Y Ko

Format Sitasi

APA MLA BibTeX

Wagner, H., Cheng, J.W., Ko, E.Y. (2017). Role of reactive oxygen species in male infertility: An updated review of literature. https://doi.org/10.1016/j.aju.2017.11.001

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.aju.2017.11.001

Informasi Jurnal

Tahun Terbit: 2017
Bahasa: en
Total Sitasi: 298×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.aju.2017.11.001
Akses: Open Access ✓