Semantic Scholar Open Access 2014 402 sitasi

The emergence of peptides in the pharmaceutical business: From exploration to exploitation

T. Uhlig Themis-Dimitrios Kyprianou F. Martinelli Carlo Alberto Oppici D. Heiligers +3 lainnya

Lihat Sumber DOI

Abstrak

This minireview touches upon the challenges and opportunities peptides experience on the track to become an approved pharmaceutical. Peptide attributes originally considered troublesome with respect to drug development may now turn out to be more convenient rather than unfavourable. Besides characteristic high target affinity, biological peptides often exhibit higher than expected stability. Clearly natural selective pressure has optimised these biomolecules beyond what can be anticipated solely on the basis of their chemical nature. This concept is gradually finding its way into the pharma and biotech industry, as illustrated by a rise in medicinal peptide patent applications and developmental work.

Topik & Kata Kunci

Business

Penulis (8)

T. Uhlig

Themis-Dimitrios Kyprianou

F. Martinelli

Carlo Alberto Oppici

D. Heiligers

D. Hills

Xavier Ribes Calvo

P. Verhaert

Format Sitasi

APA MLA BibTeX

Uhlig, T., Kyprianou, T., Martinelli, F., Oppici, C.A., Heiligers, D., Hills, D. et al. (2014). The emergence of peptides in the pharmaceutical business: From exploration to exploitation. https://doi.org/10.1016/J.EUPROT.2014.05.003

Akses Cepat

Lihat di Sumber doi.org/10.1016/J.EUPROT.2014.05.003

Informasi Jurnal

Tahun Terbit: 2014
Bahasa: en
Total Sitasi: 402×
Sumber Database: Semantic Scholar
DOI: 10.1016/J.EUPROT.2014.05.003
Akses: Open Access ✓