Semantic Scholar Open Access 2020 1387 sitasi

Sex and gender: modifiers of health, disease, and medicine

F. Mauvais-Jarvis N. Merz P. Barnes R. Brinton J. Carrero +15 lainnya

Lihat Sumber DOI

Abstrak

Clinicians can encounter sex and gender disparities in diagnostic and therapeutic responses. These disparities are noted in epidemiology, pathophysiology, clinical manifestations, disease progression, and response to treatment. This Review discusses the fundamental influences of sex and gender as modifiers of the major causes of death and morbidity. We articulate how the genetic, epigenetic, and hormonal influences of biological sex influence physiology and disease, and how the social constructs of gender affect the behaviour of the community, clinicians, and patients in the health-care system and interact with pathobiology. We aim to guide clinicians and researchers to consider sex and gender in their approach to diagnosis, prevention, and treatment of diseases as a necessary and fundamental step towards precision medicine, which will benefit men's and women's health.

Topik & Kata Kunci

Medicine

Penulis (20)

F. Mauvais-Jarvis

N. Merz

P. Barnes

R. Brinton

J. Carrero

D. Demeo

G. J. Vries

C. Epperson

R. Govindan

S. Klein

A. Lonardo

P. Maki

L. McCullough

Vera Regitz-Zagrosek

J. Regensteiner

J. Rubin

K. Sandberg

Ayako Suzuki

Format Sitasi

APA MLA BibTeX

Mauvais-Jarvis, F., Merz, N., Barnes, P., Brinton, R., Carrero, J., Demeo, D. et al. (2020). Sex and gender: modifiers of health, disease, and medicine. https://doi.org/10.1016/S0140-6736(20)31561-0

Akses Cepat

Lihat di Sumber doi.org/10.1016/S0140-6736(20)31561-0

Informasi Jurnal

Tahun Terbit: 2020
Bahasa: en
Total Sitasi: 1387×
Sumber Database: Semantic Scholar
DOI: 10.1016/S0140-6736(20)31561-0
Akses: Open Access ✓