Semantic Scholar Open Access 2020 88 sitasi

Relmacabtagene autoleucel (relma‐cel) CD19 CAR‐T therapy for adults with heavily pretreated relapsed/refractory large B‐cell lymphoma in China

Z. Ying Haiyan Yang Ye Guo Wenyu Li D. Zou +11 lainnya

Abstrak

Despite numerous chimeric antigen receptor T‐cell (CAR‐T) trials conducted in China, no CAR‐T has been registered in the country. Furthermore, China law and regulations restrict the export of patient material for CAR‐T manufacture abroad. Relma‐cel (JWCAR029), an anti‐CD19 product produced with a commercial‐ready process in China, was evaluated in the first prospective, single‐arm, multicenter, pivotal study of CAR‐T therapy conducted under Chinese IND to support an NMPA‐accepted BLA submission in relapsed/refractory (r/r) LBCL (NCT04089215).

Topik & Kata Kunci

Penulis (16)

Z

Z. Ying

H

Haiyan Yang

Y

Ye Guo

W

Wenyu Li

D

D. Zou

D

Dao-bin Zhou

Z

Zhao Wang

M

Mingzhi Zhang

J

Jianqiu Wu

H

Hui Liu

P

Pian Zhang

S

Su Yang

Z

Zisong Zhou

H

Hongxia Zheng

Y

Yuqin Song

J

Jun Zhu

Format Sitasi

Ying, Z., Yang, H., Guo, Y., Li, W., Zou, D., Zhou, D. et al. (2020). Relmacabtagene autoleucel (relma‐cel) CD19 CAR‐T therapy for adults with heavily pretreated relapsed/refractory large B‐cell lymphoma in China. https://doi.org/10.1002/cam4.3686

Akses Cepat

Lihat di Sumber doi.org/10.1002/cam4.3686
Informasi Jurnal
Tahun Terbit
2020
Bahasa
en
Total Sitasi
88×
Sumber Database
Semantic Scholar
DOI
10.1002/cam4.3686
Akses
Open Access ✓