Semantic Scholar Open Access 2011 2447 sitasi

Pericytes: developmental, physiological, and pathological perspectives, problems, and promises.

A. Armulik G. Genové C. Betsholtz

Lihat Sumber DOI

Abstrak

Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators of vascular morphogenesis and function during development, cardiovascular homeostasis, and disease. Pericytes are implicated in the development of diabetic retinopathy and tissue fibrosis, and they are potential stromal targets for cancer therapy. Some pericytes are probably mesenchymal stem or progenitor cells, which give rise to adipocytes, cartilage, bone, and muscle. However, there is still confusion about the identity, ontogeny, and progeny of pericytes. Here, we review the history of these investigations, indicate emerging concepts, and point out problems and promise in the field of pericyte biology.

Topik & Kata Kunci

Biology Medicine

Penulis (3)

A. Armulik

G. Genové

C. Betsholtz

Format Sitasi

APA MLA BibTeX

Armulik, A., Genové, G., Betsholtz, C. (2011). Pericytes: developmental, physiological, and pathological perspectives, problems, and promises.. https://doi.org/10.1016/j.devcel.2011.07.001

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.devcel.2011.07.001

Informasi Jurnal

Tahun Terbit: 2011
Bahasa: en
Total Sitasi: 2447×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.devcel.2011.07.001
Akses: Open Access ✓