Semantic Scholar Open Access 2020 1426 sitasi

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

D. Nepogodiev J. Glasbey E. Li O. Omar J. Simoes +495 lainnya

Lihat Sumber DOI

Abstrak

Summary Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p<0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p<0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p<0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research.

Topik & Kata Kunci

Medicine

Penulis (500)

D. Nepogodiev

J. Glasbey

E. Li

O. Omar

J. Simoes

T. Abbott

Osaid Alser, MD, MSc (Oxon)

A. Arnaud

B. Bankhead-Kendall

K. Breen

M. Cunha

G. Davidson

S. di Saverio

G. Gallo

E. Griffiths

R. Gujjuri

P. Hutchinson

H. Kaafarani

H. Lederhuber

M. Löffler

H. Mashbari

A. Minaya-Bravo

D. Morton

D. Moszkowicz

F. Pata

G. Tsoulfas

M. Venn

A. Bhangu

D. Cox

A. Roslani

F. Alakaloko

J. D. de Vries

M. A. Aaraj

S. Abbott

M. Abdalla

A. Abdelaal

A. Ademuyiwa

T. Aherne

O. Ali

G. Alkadeeki

A. C. Almeida

M. Alrahawy

G. Ambler

E. Alameer

S. Andreani

B. De Andrés-Asenjo

L. L. Antoñanzas

S. Aoun

F. Ashoush

K. Augestad

R. Avellana

F. Ayeni

J. Ayorinde

B. Babu

M. Baig

O. Bajomo

O. Baker

M. Baker

A. Baldwin

V. Ban

R. Baron

A. G. Barranquero

C. Barry

A. Di bartolomeo

Gary Alan Bass

M. Bath

H. Batjer

A. Beamish

A. Belgaumkar

M. Bence

R. Benson

J. C. Bernal-Sprekelsen

A. Bhama

A. Bhavaraju

W. Biffl

C. Blundell

A. Boddy

A. Borgstein

D. Bosanquet

K. Bosch

A. Bouhuwaish

M. Bozkurt

Collin Brathwaite

B. Brown

Oliver D Brown

Allison Brown

I. Buarque

A. Bueno-Cañones

M. Bulugma

J. Burke

M. Byrne

Elima P Cagigal-Ortega

R. Callcut

F. Di Candido

M. Canova

W. Carlos

E. Caruana

L. Cato

A. Catton

A. P. Ceretti

T. Chase

F. Chiara

A. Chowdhury

E. Chung

P. Cicerchia

E. Clough

Natasha L Coleman

C. Collins

M. Collins

E. Colonna

L. Comini

T. Connolly

P. Coughlin

Laura Fernández-Gomez Cruzado

B. Davidson

R. Davies

E. Davies

Niall F. Davis

B. E. Dawson

Benjamin John Floyd Dean

M. G. Delgado

J. Diaz

K. Dickson

M. Díez-Alonso

J. R. Dixon

M. Doe

T. Drake

F. T. Drake

J. Duffy

D. Dunne

N. Dunne

V. Durán-Muñoz-Cruzado

A. Durst

N. Eardley

J. Edwards

A. Elfallal

M. Elfiky

J. Elliott

S. Emile

K. Emslie

F. Endorf

J. Engel

D. Enjuto

E. Etchill

J. Evans

B. Fahey

C. Faria

C. Feo

H. Ferguson

B. Fernandez

A. G. Fernández

A. J. Fernández

Borja Camacho Fernández-Pacheco

J. Fitzgerald

G. B. Fonsi

Roser Farré Font

A. Fowler

G. Franco

Kenneth Fretwell

Lorena Sanchon Fructuoso

G. Fusai

Miguel Teodoro Hernandez Garcia

M. Garcia-Urena

C. Gill

S. Gisbertz

R. Del Giudice

M. Giuffrida

M. Di Giuseppe

Maria F. Gomez

J. González

C. Guariglia

A. Hainsworth

Bria J. Hall

J. R. Hall

J. Hammond

M. Haqqani

E. Harrison

J. Hazelton

M. van Heinsbergen

A. Hill

C. Hing

S. Hirji

M. W. Ho

C. Holbrook

T. Holme

James C. Hopkins

D. Hopkinson

F. Hossain

V. Hudson

J. Hughes

E. Hwang

M. Ibrahim

Simone M. Isolani

P. Jara

M. Jenkinson

H. Jenny

D. Jeyaretna

R. Jones

Andrew P. Jones

P. Jonker

M. Jönsson

D. Joyce

K. Kalkwarf

S. Kamarajah

M. El kassas

D. Kavanagh

J. Keatley

M. Khalefa

J. Khan

B. Kirmani

A. Kisiel

S. Kouris

M. Kowal

P. Labib

J. Larkin

J. Lauscher

W. Leclercq

Frances Ledesma

A. Leite-Moreira

E. Leung

S. Lewis

M. J. Lima

Daniel J. Lin

Helen Liu

A. Lowery

S. Lozano

C. Luney

Mariana Maia

N. Mariani

M. Marino

A. Marra

C. Marsh

R. C. Martin

S. McCluney

R. McIntyre

S. Mckay

K. McKevitt

A. Meagher

M. Mehdi

B. Mehigan

Melania Gonzalez-De Miguel

M. De Miguel-Ardevines

Carlos San Miguel-Méndez

S. Mills

H. Mohan

J. Moir

J. Monson

J. Monteiro

M. T. Montella

C. Montesinos

M. Morgom

F. Moura

J. Muguerza

S. Murphy

P. De Nardi

D. Naumann

P. Neary

D. Neely

J. Ng-Kamstra

A. Ngu

T. Nguyen

G. Niță

Q. Nunes

R. Nygaard

L. O'Meara

J. R. O'Neill

B. Okafor

S. Olson

A. Oo

P. C. Ormazabal

A. Osorio

M. Pachl

J. Parry

P. Patel

D. D. Pérez

C. Pérez

L. E. Pérez-Sánchez

Ana Nogués Pevidal

A. P. Pezzuto

M. Philp

T. Pinkney

J. Pollok

M. Povey

A. A. Poza

A. Rajgor

J. Rao

D. Raptis

H. Rice

P. Ridgway

A. Rivas

J. C. Rodríguez-Sanjuán

L. Rogers

A. Da Roit

R. Rollett

J. L. Romera

S. Rooney

V. Roxo

B. Le Roy

E. Rubio

C. Ruiz

M. Ruiz

É. Ryan

Abdel Rahman Saad

S. Saeed

Hiba A Salama

Abdulrauf A Salamah

María Gutiérrez Samaniego

G. Sampietro

D. Sarma

K. Schaffer

A. Schnitzbauer

R. Scurrah

O. Serevina

P. Serralheiro

J. Sewards

M. Shackcloth

A. Shaw

A. Sheel

G. Sica

V. De Simone

A. Singh

Rabindra P Singh

B. Skelly

Henry G. Smith

Amir H. Sohail

D. Spalding

L. Springford

A. Ssentongo

P. Steinkamp

K. Stevens

G. Stewart

N. Stylianides

T. Sullivan

A. Taher

M. Tamimy

A. Tang

G. Tebala

F. J. Tejero-Pintor

M. Thaha

Amy Thomas

G. De Toma

F. la Torre

A. Torres

D. Townshend

I. Trout

S. Tucker

H. Ubhi

V. Vega

G. Velmahos

C. Velopulos

Y. Viswanath

A. Vivas

R. Wade

M. Wadley

J. Wall

A. Walters

O. Warren

C. Weerasinghe

R. Wilkin

K. Williams

S. Winter

J. Wormald

F. Wright

S. Xyda

A. Young

M. Youssef

F. B. Yousuf

H. El Youzouri

M. Zappa

E. Abate

H. Abdalaziz

M. Abdelkarim

Hossam Abdou

Ahmad Aboelkassem-Ibrahim

A. Abuown

F. Acebes-García

M. Acharya

M. Adamina

E. Addae-Boateng

R. Aftab

A. Agarwal

J. Aguilar

Yousra Ahmed

E. Aitken

M. Al-Azzawi

S. Al-Embideen

M. Al-Masri

H. Al-Najjar

A. Al-Sukaini

R. Alam

D. Alderson

Z. Aliyeva

Firas Aljanadi

M. Almasri

Paula Alonso-Ortuño

F. Altıntoprak

G. Amira

Rabbia Amjad

G. Anania

T. Andabaka

D. Angelou

S. Annamalai

V. Annessi

J. Anthoney

S. Anwar

M. Anwer

J. Aragón-Chamizo

A. Ardito

M. Arigoni

T. Armao

A. Arminio

L. Armstrong

A. Arnaud

P. Asaad

J. Ashcroft

C. Ashmore

A. Asqalan

E. Asti

E. Aubry

E. Aytaç

Esther Ayuso-Herrera

M. Baeza

M. Bailon-Cuadrado

B. Bakmaz

C. Baldi

E. Baldini

Stefano Baldo

M. Ballabio

I. Baloyiannis

G. Baltazar

F. Bàmbina

A. Bandiera

E. Barlow

R. Barmasse

C. Barmpagianni

G. Baronio

F. Barra

A. Bartsch

A. Basgaran

A. Basha

V. Bashkirova

M. Bastazza

R. Baumber

E. Belcher

A. Belvedere

I. Benítez-Linero

D. Bergeat

M. Bernasconi

A. Bhalla

N. Bhutiani

F. Bianco

P. Bisagni

I. Blake

R. Blanco‐Colino

Alma Blázquez-Martín

M. Boal

L. Bonavina

G. Bonavina

G. Bond-Smith

K. Booth

F. Borges

F. Borghi

K. Bouchagier

G. Bourke

E. Boyle

G. Brachini

J. Brain

A. Brar

Lisa Breckles

F. Brétagnol

G. Brixton

P. Bruzzaniti

T. Bueser

N. Burnside

A. Caballero

Enrique Calcerrada-Alises

Miriam Callahan

E. Camarero

T. Campagnaro

M. Campanelli

M. Candiani

M. Cannoletta

M. Cantalejo-Díaz

H. Cao

P. Capelli

V. Capizzi

G. Carcano

F. Carissimi

M. Carlini

M. Carlucci

H. Carmichael

M. Carrasco

M. Carrillo

M. Carvello

M. Casati

C. Castoro

V. Catalán

S. Cavaleiro

P. Cellerino

G. Centinaio

Format Sitasi

APA MLA BibTeX

Nepogodiev, D., Glasbey, J., Li, E., Omar, O., Simoes, J., Abbott, T. et al. (2020). Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study. https://doi.org/10.1016/S0140-6736(20)31182-X

@article{nepogodiev2020, author = {D. Nepogodiev and J. Glasbey and E. Li and O. Omar and J. Simoes and T. Abbott and Osaid Alser, MD, MSc (Oxon) and A. Arnaud and B. Bankhead-Kendall and K. Breen and M. Cunha and G. Davidson and S. di Saverio and G. Gallo and E. Griffiths and R. Gujjuri and P. Hutchinson and H. Kaafarani and H. Lederhuber and M. Löffler and H. Mashbari and A. Minaya-Bravo and D. Morton and D. Moszkowicz and F. Pata and G. Tsoulfas and M. Venn and A. Bhangu and D. Cox and A. Roslani and F. Alakaloko and J. D. de Vries and M. A. Aaraj and S. Abbott and M. Abdalla and A. Abdelaal and A. Ademuyiwa and T. Aherne and O. Ali and G. Alkadeeki and A. C. Almeida and M. Alrahawy and G. Ambler and E. Alameer and S. Andreani and B. De Andrés-Asenjo and L. L. Antoñanzas and S. Aoun and F. Ashoush and K. Augestad and R. Avellana and F. Ayeni and J. Ayorinde and B. Babu and M. Baig and O. Bajomo and O. Baker and M. Baker and A. Baldwin and V. Ban and R. Baron and A. G. Barranquero and C. Barry and A. Di bartolomeo and Gary Alan Bass and M. Bath and H. Batjer and A. Beamish and A. Belgaumkar and M. Bence and R. Benson and J. C. Bernal-Sprekelsen and A. Bhama and A. Bhavaraju and W. Biffl and C. Blundell and A. Boddy and A. Borgstein and D. Bosanquet and K. Bosch and A. Bouhuwaish and M. Bozkurt and Collin Brathwaite and B. Brown and Oliver D Brown and Allison Brown and I. Buarque and A. Bueno-Cañones and M. Bulugma and J. Burke and M. Byrne and Elima P Cagigal-Ortega and R. Callcut and F. Di Candido and M. Canova and W. Carlos and E. Caruana and L. Cato and A. Catton and A. P. Ceretti and T. Chase and F. Chiara and A. Chowdhury and E. Chung and P. Cicerchia and E. Clough and Natasha L Coleman and C. Collins and M. Collins and E. Colonna and L. Comini and T. Connolly and P. Coughlin and Laura Fernández-Gomez Cruzado and B. Davidson and R. Davies and E. Davies and Niall F. Davis and B. E. Dawson and Benjamin John Floyd Dean and M. G. Delgado and J. Diaz and K. Dickson and M. Díez-Alonso and J. R. Dixon and M. Doe and T. Drake and F. T. Drake and J. Duffy and D. Dunne and N. Dunne and V. Durán-Muñoz-Cruzado and A. Durst and N. Eardley and J. Edwards and A. Elfallal and M. Elfiky and J. Elliott and S. Emile and K. Emslie and F. Endorf and J. Engel and D. Enjuto and E. Etchill and J. Evans and B. Fahey and C. Faria and C. Feo and H. Ferguson and B. Fernandez and A. G. Fernández and A. J. Fernández and Borja Camacho Fernández-Pacheco and J. Fitzgerald and G. B. Fonsi and Roser Farré Font and A. Fowler and G. Franco and Kenneth Fretwell and Lorena Sanchon Fructuoso and G. Fusai and Miguel Teodoro Hernandez Garcia and M. Garcia-Urena and C. Gill and S. Gisbertz and R. Del Giudice and M. Giuffrida and M. Di Giuseppe and Maria F. Gomez and J. González and C. Guariglia and A. Hainsworth and Bria J. Hall and J. R. Hall and J. Hammond and M. Haqqani and E. Harrison and J. Hazelton and M. van Heinsbergen and A. Hill and C. Hing and S. Hirji and M. W. Ho and C. Holbrook and T. Holme and James C. Hopkins and D. Hopkinson and F. Hossain and V. Hudson and J. Hughes and E. Hwang and M. Ibrahim and Simone M. Isolani and P. Jara and M. Jenkinson and H. Jenny and D. Jeyaretna and R. Jones and Andrew P. Jones and P. Jonker and M. Jönsson and D. Joyce and K. Kalkwarf and S. Kamarajah and M. El kassas and D. Kavanagh and J. Keatley and M. Khalefa and J. Khan and B. Kirmani and A. Kisiel and S. Kouris and M. Kowal and P. Labib and J. Larkin and J. Lauscher and W. Leclercq and Frances Ledesma and A. Leite-Moreira and E. Leung and S. Lewis and M. J. Lima and Daniel J. Lin and Helen Liu and A. Lowery and S. Lozano and C. Luney and Mariana Maia and N. Mariani and M. Marino and A. Marra and C. Marsh and R. C. Martin and S. McCluney and R. McIntyre and S. Mckay and K. McKevitt and A. Meagher and M. Mehdi and B. Mehigan and Melania Gonzalez-De Miguel and M. De Miguel-Ardevines and Carlos San Miguel-Méndez and S. Mills and H. Mohan and J. Moir and J. Monson and J. Monteiro and M. T. Montella and C. Montesinos and M. Morgom and F. Moura and J. Muguerza and S. Murphy and P. De Nardi and D. Naumann and P. Neary and D. Neely and J. Ng-Kamstra and A. Ngu and T. Nguyen and G. Niță and Q. Nunes and R. Nygaard and L. O'Meara and J. R. O'Neill and B. Okafor and S. Olson and A. Oo and P. C. Ormazabal and A. Osorio and M. Pachl and J. Parry and P. Patel and D. D. Pérez and C. Pérez and L. E. Pérez-Sánchez and Ana Nogués Pevidal and A. P. Pezzuto and M. Philp and T. Pinkney and J. Pollok and M. Povey and A. A. Poza and A. Rajgor and J. Rao and D. Raptis and H. Rice and P. Ridgway and A. Rivas and J. C. Rodríguez-Sanjuán and L. Rogers and A. Da Roit and R. Rollett and J. L. Romera and S. Rooney and V. Roxo and B. Le Roy and E. Rubio and C. Ruiz and M. Ruiz and É. Ryan and Abdel Rahman Saad and S. Saeed and Hiba A Salama and Abdulrauf A Salamah and María Gutiérrez Samaniego and G. Sampietro and D. Sarma and K. Schaffer and A. Schnitzbauer and R. Scurrah and O. Serevina and P. Serralheiro and J. Sewards and M. Shackcloth and A. Shaw and A. Sheel and G. Sica and V. De Simone and A. Singh and Rabindra P Singh and B. Skelly and Henry G. Smith and Amir H. Sohail and D. Spalding and L. Springford and A. Ssentongo and P. Steinkamp and K. Stevens and G. Stewart and N. Stylianides and T. Sullivan and A. Taher and M. Tamimy and A. Tang and G. Tebala and F. J. Tejero-Pintor and M. Thaha and Amy Thomas and G. De Toma and F. la Torre and A. Torres and D. Townshend and I. Trout and S. Tucker and H. Ubhi and V. Vega and G. Velmahos and C. Velopulos and Y. Viswanath and A. Vivas and R. Wade and M. Wadley and J. Wall and A. Walters and O. Warren and C. Weerasinghe and R. Wilkin and K. Williams and S. Winter and J. Wormald and F. Wright and S. Xyda and A. Young and M. Youssef and F. B. Yousuf and H. El Youzouri and M. Zappa and E. Abate and H. Abdalaziz and M. Abdelkarim and Hossam Abdou and Ahmad Aboelkassem-Ibrahim and A. Abuown and F. Acebes-García and M. Acharya and M. Adamina and E. Addae-Boateng and R. Aftab and A. Agarwal and J. Aguilar and Yousra Ahmed and E. Aitken and M. Al-Azzawi and S. Al-Embideen and M. Al-Masri and H. Al-Najjar and A. Al-Sukaini and R. Alam and D. Alderson and Z. Aliyeva and Firas Aljanadi and M. Almasri and Paula Alonso-Ortuño and F. Altıntoprak and G. Amira and Rabbia Amjad and G. Anania and T. Andabaka and D. Angelou and S. Annamalai and V. Annessi and J. Anthoney and S. Anwar and M. Anwer and J. Aragón-Chamizo and A. Ardito and M. Arigoni and T. Armao and A. Arminio and L. Armstrong and A. Arnaud and P. Asaad and J. Ashcroft and C. Ashmore and A. Asqalan and E. Asti and E. Aubry and E. Aytaç and Esther Ayuso-Herrera and M. Baeza and M. Bailon-Cuadrado and B. Bakmaz and C. Baldi and E. Baldini and Stefano Baldo and M. Ballabio and I. Baloyiannis and G. Baltazar and F. Bàmbina and A. Bandiera and E. Barlow and R. Barmasse and C. Barmpagianni and G. Baronio and F. Barra and A. Bartsch and A. Basgaran and A. Basha and V. Bashkirova and M. Bastazza and R. Baumber and E. Belcher and A. Belvedere and I. Benítez-Linero and D. Bergeat and M. Bernasconi and A. Bhalla and N. Bhutiani and F. Bianco and P. Bisagni and I. Blake and R. Blanco‐Colino and Alma Blázquez-Martín and M. Boal and L. Bonavina and G. Bonavina and G. Bond-Smith and K. Booth and F. Borges and F. Borghi and K. Bouchagier and G. Bourke and E. Boyle and G. Brachini and J. Brain and A. Brar and Lisa Breckles and F. Brétagnol and G. Brixton and P. Bruzzaniti and T. Bueser and N. Burnside and A. Caballero and Enrique Calcerrada-Alises and Miriam Callahan and E. Camarero and T. Campagnaro and M. Campanelli and M. Candiani and M. Cannoletta and M. Cantalejo-Díaz and H. Cao and P. Capelli and V. Capizzi and G. Carcano and F. Carissimi and M. Carlini and M. Carlucci and H. Carmichael and M. Carrasco and M. Carrillo and M. Carvello and M. Casati and C. Castoro and V. Catalán and S. Cavaleiro and P. Cellerino and G. Centinaio}, title = {Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study}, year = {2020}, journal = {Semantic Scholar}, doi = {10.1016/S0140-6736(20)31182-X}, url = {https://www.semanticscholar.org/paper/7a482ec2ed1256a05e559efb9766c39c24beb87d}, }

Akses Cepat

Lihat di Sumber doi.org/10.1016/S0140-6736(20)31182-X

Informasi Jurnal

Tahun Terbit: 2020
Bahasa: en
Total Sitasi: 1426×
Sumber Database: Semantic Scholar
DOI: 10.1016/S0140-6736(20)31182-X
Akses: Open Access ✓