Semantic Scholar Open Access 2022 93 sitasi

Advancements, challenges and future perspectives on peptide-based drugs: Focus on antimicrobial peptides.

Xiaofang Luo Huifang Chen Ya Song Zuodong Qin Lijian Xu +3 lainnya

Lihat Sumber DOI

Abstrak

Among other health related issues, the rising concerns on drug resistance led to look for alternative pharmaceutical drugs that are effective both against infectious and noninfectious diseases. Antimicrobial peptides (AMPs) emerged as potential therapeutic molecule with wide range of applications. With their limitations, AMPs have gained reputable attentions in research as well as in the pharmaceutical industry. This review highlighted the historical background, research trends, technological advancements, challenges, and future perspectives in the development and applications of peptide drugs. Some vital questions related with the need for pharmaceutical production, factors for the slow and steady journey, the importance of oral bioavailability, and the drug resistance possibilities of AMPs were raised and addressed accordingly. Therefore, the current study is believed to provide a profound understanding in the past and current scenarios and future directions on the therapeutic impacts of peptide drugs.

Topik & Kata Kunci

Medicine

Penulis (8)

Xiaofang Luo

Huifang Chen

Ya Song

Zuodong Qin

Lijian Xu

N. He

Yimin Tan

Wubliker Dessie

Format Sitasi

APA MLA BibTeX

Luo, X., Chen, H., Song, Y., Qin, Z., Xu, L., He, N. et al. (2022). Advancements, challenges and future perspectives on peptide-based drugs: Focus on antimicrobial peptides.. https://doi.org/10.1016/j.ejps.2022.106363

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.ejps.2022.106363

Informasi Jurnal

Tahun Terbit: 2022
Bahasa: en
Total Sitasi: 93×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.ejps.2022.106363
Akses: Open Access ✓