Semantic Scholar Open Access 2017 322 sitasi

Genomic adaptation to polyphagy and insecticides in a major East Asian noctuid pest

Tingcai Cheng Jiaqi Wu Yuqian Wu R. Chilukuri Lihua Huang +33 lainnya

Lihat Sumber DOI

Abstrak

The tobacco cutworm, Spodoptera litura, is among the most widespread and destructive agricultural pests, feeding on over 100 crops throughout tropical and subtropical Asia. By genome sequencing, physical mapping and transcriptome analysis, we found that the gene families encoding receptors for bitter or toxic substances and detoxification enzymes, such as cytochrome P450, carboxylesterase and glutathione-S-transferase, were massively expanded in this polyphagous species, enabling its extraordinary ability to detect and detoxify many plant secondary compounds. Larval exposure to insecticidal toxins induced expression of detoxification genes, and knockdown of representative genes using short interfering RNA (siRNA) reduced larval survival, consistent with their contribution to the insect’s natural pesticide tolerance. A population genetics study indicated that this species expanded throughout southeast Asia by migrating along a South India–South China–Japan axis, adapting to wide-ranging ecological conditions with diverse host plants and insecticides, surviving and adapting with the aid of its expanded detoxification systems. The findings of this study will enable the development of new pest management strategies for the control of major agricultural pests such as S. litura. Genome of the tobacco cutworm, Spodoptera litura, which is one of the most widespread and destructive agricultural pests in tropical and subtropical Asia.

Topik & Kata Kunci

Biology Medicine

Penulis (38)

Tingcai Cheng

Jiaqi Wu

Yuqian Wu

R. Chilukuri

Lihua Huang

Kohji Yamamoto

Li Feng

Wanshun Li

Zhiwei Chen

Huizhen Guo

Jianqiu Liu

Shenglong Li

Xiaoxiao Wang

Li Peng

Duolian Liu

Youbing Guo

Bohua Fu

Zhiqing Li

Chun Liu

Yuhui Chen

A. Tomar

F. Hilliou

N. Montagné

E. Jacquin‐Joly

E. d’Alençon

R. Seth

R. Bhatnagar

A. Jouraku

T. Shiotsuki

K. Kadono‐Okuda

A. Promboon

G. Smagghe

K. P. Arunkumar

H. Kishino

M. Goldsmith

Q. Feng

Q. Xia

K. Mita

Format Sitasi

APA MLA BibTeX

Cheng, T., Wu, J., Wu, Y., Chilukuri, R., Huang, L., Yamamoto, K. et al. (2017). Genomic adaptation to polyphagy and insecticides in a major East Asian noctuid pest. https://doi.org/10.1038/s41559-017-0314-4

Akses Cepat

Lihat di Sumber doi.org/10.1038/s41559-017-0314-4

Informasi Jurnal

Tahun Terbit: 2017
Bahasa: en
Total Sitasi: 322×
Sumber Database: Semantic Scholar
DOI: 10.1038/s41559-017-0314-4
Akses: Open Access ✓