Semantic Scholar
Open Access
2024
6 sitasi
Therapeutic Potential of Clusterin Inhibition in Human Cancer
D. Martín-García
M. García-Aranda
Maximino Redondo
Abstrak
Clusterin (CLU) protein is involved in various pathophysiological processes including carcinogenesis and tumor progression. In recent years, the role of the secretory isoform has been demonstrated in tumor cells, where it inhibits apoptosis and favors the acquisition of resistance to conventional treatments used to treat cancer. To determine the possible therapeutic potential of inhibiting this protein, numerous studies have been carried out in this field. In this article, we present the existing knowledge to date on the inhibition of this protein in different types of cancer and analyze the importance it could have in the development of new therapies targeted against this disease.
Topik & Kata Kunci
Penulis (3)
D
D. Martín-García
M
M. García-Aranda
M
Maximino Redondo
Akses Cepat
Informasi Jurnal
- Tahun Terbit
- 2024
- Bahasa
- en
- Total Sitasi
- 6×
- Sumber Database
- Semantic Scholar
- DOI
- 10.3390/cells13080665
- Akses
- Open Access ✓