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Semantic Scholar Open Access 2019 16 sitasi

Phase 1 clinical study to assess the safety of a novel drug delivery system providing long‐term topical steroid therapy for chronic rhinosinusitis

R. Douglas A. Psaltis J. Rimmer Tom Kuruvilla A. Cervin +1 lainnya
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Abstrak

Chronic rhinosinusitis (CRS) patients who fail medical management have few treatment options other than endoscopic sinus surgery (ESS). A novel biodegradable mometasone furoate drug delivery system (LYR‐210) providing continuous topical steroid therapy to sinonasal mucosa over 24 weeks was developed to treat unoperated CRS patients who have failed medical management prior to ESS. LYR‐210 was designed to slowly expand in the middle meatus, ensuring efficient drug delivery as mucosal swelling reduces.

Topik & Kata Kunci

Medicine

Penulis (6)

R

R. Douglas

A

A. Psaltis

J

J. Rimmer

T

Tom Kuruvilla

A

A. Cervin

Y

Yina Kuang

Format Sitasi

APA MLA BibTeX
Douglas, R., Psaltis, A., Rimmer, J., Kuruvilla, T., Cervin, A., Kuang, Y. (2019). Phase 1 clinical study to assess the safety of a novel drug delivery system providing long‐term topical steroid therapy for chronic rhinosinusitis. https://doi.org/10.1002/alr.22288

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Informasi Jurnal
Tahun Terbit
2019
Bahasa
en
Total Sitasi
16×
Sumber Database
Semantic Scholar
DOI
10.1002/alr.22288
Akses
Open Access ✓