Semantic Scholar Open Access 2019 731 sitasi

Mesenchymal Stem Cells for Regenerative Medicine

Yuping Han Xue-zhou Li Yanbo Zhang Yuping Han F. Chang +1 lainnya

Lihat Sumber DOI

Abstrak

In recent decades, the biomedical applications of mesenchymal stem cells (MSCs) have attracted increasing attention. MSCs are easily extracted from the bone marrow, fat, and synovium, and differentiate into various cell lineages according to the requirements of specific biomedical applications. As MSCs do not express significant histocompatibility complexes and immune stimulating molecules, they are not detected by immune surveillance and do not lead to graft rejection after transplantation. These properties make them competent biomedical candidates, especially in tissue engineering. We present a brief overview of MSC extraction methods and subsequent potential for differentiation, and a comprehensive overview of their preclinical and clinical applications in regenerative medicine, and discuss future challenges.

Topik & Kata Kunci

Medicine

Penulis (6)

Yuping Han

Xue-zhou Li

Yanbo Zhang

Yuping Han

F. Chang

Jianxun Ding

Format Sitasi

APA MLA BibTeX

Han, Y., Li, X., Zhang, Y., Han, Y., Chang, F., Ding, J. (2019). Mesenchymal Stem Cells for Regenerative Medicine. https://doi.org/10.3390/cells8080886

Akses Cepat

Lihat di Sumber doi.org/10.3390/cells8080886

Informasi Jurnal

Tahun Terbit: 2019
Bahasa: en
Total Sitasi: 731×
Sumber Database: Semantic Scholar
DOI: 10.3390/cells8080886
Akses: Open Access ✓