The genetic prehistory of southern Africa
Abstrak
Southern and eastern African populations that speak non-Bantu languages with click consonants are known to harbour some of the most ancient genetic lineages in humans, but their relationships are poorly understood. Here, we report data from 23 populations analysed at over half a million single-nucleotide polymorphisms, using a genome-wide array designed for studying human history. The southern African Khoisan fall into two genetic groups, loosely corresponding to the northwestern and southeastern Kalahari, which we show separated within the last 30,000 years. We find that all individuals derive at least a few percent of their genomes from admixture with non-Khoisan populations that began ∼1,200 years ago. In addition, the East African Hadza and Sandawe derive a fraction of their ancestry from admixture with a population related to the Khoisan, supporting the hypothesis of an ancient link between southern and eastern Africa. Hunter-gatherer populations in Africa preserve unique information about human history, but genetic sub-structures of these populations remain unclear. Using newly designed microarray and statistical methods, these authors analyse genetic compositions of southern African populations and reveal an ancient link between southern and eastern Africa.
Penulis (21)
Joseph K. Pickrell
N. Patterson
Chiara Barbieri
Falko Berthold
Linda Gerlach
Tom Güldemann
Blesswell Kure
S. Mpoloka
Hirosi Nakagawa
Christfried Naumann
Mark Lipson
Po-Ru Loh
J. Lachance
J. Mountain
C. Bustamante
B. Berger
S. Tishkoff
B. Henn
M. Stoneking
D. Reich
B. Pakendorf
Akses Cepat
- Tahun Terbit
- 2012
- Bahasa
- en
- Total Sitasi
- 307×
- Sumber Database
- Semantic Scholar
- DOI
- 10.1038/ncomms2140
- Akses
- Open Access ✓