Semantic Scholar Open Access 2020 117 sitasi

Digoxin: Pharmacology and toxicology-A review.

J. Patočka E. Nepovimova Wenda Wu K. Kuča

Abstrak

Digoxin is a cardiac glycoside used as drug in case of heart problems, including congestive heart failure, atrial fibrillation or flutter, and certain cardiac arrhythmias. It has a very narrow therapeutic window of the medication. Digoxin is toxic substance with well known cardiotoxic effect. In this work, pharmacology and toxicology of digoxin are summarized; Its pharmacokinetics, pharmacodynamics, available acute toxicity data (different species, different administration routes) are summarized in this article. Moreover, its treatment side effect and human poisonings are thoroughly discussed. Finally, appropriate therapy regimen is proposed.

Topik & Kata Kunci

Medicine

Penulis (4)

J. Patočka

E. Nepovimova

Wenda Wu

K. Kuča

Format Sitasi

APA MLA BibTeX

Patočka, J., Nepovimova, E., Wu, W., Kuča, K. (2020). Digoxin: Pharmacology and toxicology-A review.. https://doi.org/10.1016/j.etap.2020.103400

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Informasi Jurnal

Tahun Terbit: 2020
Bahasa: en
Total Sitasi: 117×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.etap.2020.103400
Akses: Open Access ✓