Semantic Scholar Open Access 2016 219 sitasi

Biosensor-based engineering of biosynthetic pathways.

Jameson K. Rogers N. Taylor G. Church

Lihat Sumber DOI

Abstrak

Biosynthetic pathways provide an enzymatic route from inexpensive renewable resources to valuable metabolic products such as pharmaceuticals and plastics. Designing these pathways is challenging due to the complexities of biology. Advances in the design and construction of genetic variants has enabled billions of cells, each possessing a slightly different metabolic design, to be rapidly generated. However, our ability to measure the quality of these designs lags by several orders of magnitude. Recent research has enabled cells to report their own success in chemical production through the use of genetically encoded biosensors. A new engineering discipline is emerging around the creation and application of biosensors. Biosensors, implemented in selections and screens to identify productive cells, are paving the way for a new era of biotechnological progress.

Topik & Kata Kunci

Medicine

Penulis (3)

Jameson K. Rogers

N. Taylor

G. Church

Format Sitasi

APA MLA BibTeX

Rogers, J.K., Taylor, N., Church, G. (2016). Biosensor-based engineering of biosynthetic pathways.. https://doi.org/10.1016/j.copbio.2016.03.005

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.copbio.2016.03.005

Informasi Jurnal

Tahun Terbit: 2016
Bahasa: en
Total Sitasi: 219×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.copbio.2016.03.005
Akses: Open Access ✓