Semantic Scholar Open Access 2018 262 sitasi

Building Models of Brain Disorders with Three-Dimensional Organoids.

Neal D. Amin S. Pașca

Lihat Sumber DOI

Abstrak

Disorders of the nervous system are challenging to study and treat due to the relative inaccessibility of functional human brain tissue for research. Stem cell-derived 3D human brain organoids have the potential to recapitulate features of the human brain with greater complexity than 2D models and are increasingly being applied to model diseases affecting the central nervous system. Here, we review the use of human brain organoids to investigate neurological and psychiatric (neuropsychiatric) disorders and how this technology may ultimately advance our biological understanding of these conditions.

Topik & Kata Kunci

Medicine

Penulis (2)

Neal D. Amin

S. Pașca

Format Sitasi

APA MLA BibTeX

Amin, N.D., Pașca, S. (2018). Building Models of Brain Disorders with Three-Dimensional Organoids.. https://doi.org/10.1016/j.neuron.2018.10.007

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.neuron.2018.10.007

Informasi Jurnal

Tahun Terbit: 2018
Bahasa: en
Total Sitasi: 262×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.neuron.2018.10.007
Akses: Open Access ✓