Semantic Scholar Open Access 2001 1078 sitasi

Metalloproteinases in biology and pathology of the nervous system

V. W. Yong C. Power P. Forsyth D. Edwards

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Abstrak

Matrix metalloproteinases (MMPs) have been implicated in several diseases of the nervous system. Here we review the evidence that supports this idea and discuss the possible mechanisms of MMP action. We then consider some of the beneficial functions of MMPs during neural development and speculate on their roles in repair after brain injury. We also introduce a family of proteins known as ADAMs (a disintegrin and metalloproteinase), as some of the properties previously ascribed to MMPs are possibly the result of ADAM activity.

Topik & Kata Kunci

Biology Medicine

Penulis (4)

V. W. Yong

C. Power

P. Forsyth

D. Edwards

Format Sitasi

APA MLA BibTeX

Yong, V.W., Power, C., Forsyth, P., Edwards, D. (2001). Metalloproteinases in biology and pathology of the nervous system. https://doi.org/10.1038/35081571

Akses Cepat

Lihat di Sumber doi.org/10.1038/35081571

Informasi Jurnal

Tahun Terbit: 2001
Bahasa: en
Total Sitasi: 1078×
Sumber Database: Semantic Scholar
DOI: 10.1038/35081571
Akses: Open Access ✓