Semantic Scholar Open Access 2023 3 sitasi

A neuron-specific interaction between Alzheimer's disease risk factors SORL1, APOE, and CLU.

Pranav Preman Amaia M. Arranz

Lihat Sumber DOI

Abstrak

Lee et al.1 report that loss of the Alzheimer's disease risk factor SORL1 results in neuron-specific reduction in APOE and CLU, altered lipid homeostasis, and increased Aβ levels and phosphorylated Tau, both rescued by stabilizing retromer or enhancing autophagy.

Topik & Kata Kunci

Medicine

Penulis (2)

Pranav Preman

Amaia M. Arranz

Format Sitasi

APA MLA BibTeX

Preman, P., Arranz, A.M. (2023). A neuron-specific interaction between Alzheimer's disease risk factors SORL1, APOE, and CLU.. https://doi.org/10.1016/j.celrep.2023.113129

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.celrep.2023.113129

Informasi Jurnal

Tahun Terbit: 2023
Bahasa: en
Total Sitasi: 3×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.celrep.2023.113129
Akses: Open Access ✓