Semantic Scholar Open Access 2020 1811 sitasi

SMART: recent updates, new developments and status in 2020

Ivica Letunic Supriya Khedkar P. Bork

Lihat Sumber DOI

Abstrak

Abstract SMART (Simple Modular Architecture Research Tool) is a web resource (https://smart.embl.de) for the identification and annotation of protein domains and the analysis of protein domain architectures. SMART version 9 contains manually curated models for more than 1300 protein domains, with a topical set of 68 new models added since our last update article (1). All the new models are for diverse recombinase families and subfamilies and as a set they provide a comprehensive overview of mobile element recombinases namely transposase, integrase, relaxase, resolvase, cas1 casposase and Xer like cellular recombinase. Further updates include the synchronization of the underlying protein databases with UniProt (2), Ensembl (3) and STRING (4), greatly increasing the total number of annotated domains and other protein features available in architecture analysis mode. Furthermore, SMART’s vector-based protein display engine has been extended and updated to use the latest web technologies and the domain architecture analysis components have been optimized to handle the increased number of protein features available.

Topik & Kata Kunci

Medicine Computer Science Biology

Penulis (3)

Ivica Letunic

Supriya Khedkar

P. Bork

Format Sitasi

APA MLA BibTeX

Letunic, I., Khedkar, S., Bork, P. (2020). SMART: recent updates, new developments and status in 2020. https://doi.org/10.1093/nar/gkaa937

Akses Cepat

Lihat di Sumber doi.org/10.1093/nar/gkaa937

Informasi Jurnal

Tahun Terbit: 2020
Bahasa: en
Total Sitasi: 1811×
Sumber Database: Semantic Scholar
DOI: 10.1093/nar/gkaa937
Akses: Open Access ✓