Semantic Scholar Open Access 2020 173 sitasi

The applied anatomy of human skin: A model for regeneration

J. Abdo N. Sopko S. Milner

Lihat Sumber DOI

Abstrak

Abstract Autologous keratinocyte cultures and combinations of scaffolds, different cell types, solutions of macromolecules, or growth factors have contributed to the resurfacing of burns and large wounds. There are, however, significant limitations with these therapies. No tissue-engineered substitute can fully replace the split-thickness skin graft for permanent coverage of full-thickness skin loss in one step, and none contain a functional vascular plexus. Current research characterizes skin as more than a barrier with sensory function, but as an intricate biological factory participating in cell signaling, metabolism, and protein synthesis, and as a vital component of the nervous, immune and endocrine systems. This paper provides a comprehensive review of the structure and function of skin, highlighting the importance of regenerating an organ that will function physiologically.

Topik & Kata Kunci

Medicine

Penulis (3)

J. Abdo

N. Sopko

S. Milner

Format Sitasi

APA MLA BibTeX

Abdo, J., Sopko, N., Milner, S. (2020). The applied anatomy of human skin: A model for regeneration. https://doi.org/10.1016/j.wndm.2020.100179

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.wndm.2020.100179

Informasi Jurnal

Tahun Terbit: 2020
Bahasa: en
Total Sitasi: 173×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.wndm.2020.100179
Akses: Open Access ✓