Semantic Scholar Open Access 2016 1091 sitasi

The sequence of sequencers: The history of sequencing DNA

J. Heather B. Chain

Lihat Sumber DOI

Abstrak

Determining the order of nucleic acid residues in biological samples is an integral component of a wide variety of research applications. Over the last fifty years large numbers of researchers have applied themselves to the production of techniques and technologies to facilitate this feat, sequencing DNA and RNA molecules. This time-scale has witnessed tremendous changes, moving from sequencing short oligonucleotides to millions of bases, from struggling towards the deduction of the coding sequence of a single gene to rapid and widely available whole genome sequencing. This article traverses those years, iterating through the different generations of sequencing technology, highlighting some of the key discoveries, researchers, and sequences along the way.

Topik & Kata Kunci

Medicine Biology

Penulis (2)

J. Heather

B. Chain

Format Sitasi

APA MLA BibTeX

Heather, J., Chain, B. (2016). The sequence of sequencers: The history of sequencing DNA. https://doi.org/10.1016/j.ygeno.2015.11.003

Akses Cepat

Lihat di Sumber doi.org/10.1016/j.ygeno.2015.11.003

Informasi Jurnal

Tahun Terbit: 2016
Bahasa: en
Total Sitasi: 1091×
Sumber Database: Semantic Scholar
DOI: 10.1016/j.ygeno.2015.11.003
Akses: Open Access ✓