Semantic Scholar Open Access 2009 505 sitasi

Genome sequence of the recombinant protein production host Pichia pastoris

K. Schutter Yao-cheng Lin P. Tiels A. V. Hecke Sascha Glinka +4 lainnya

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Abstrak

The methylotrophic yeast Pichia pastoris is widely used for the production of proteins and as a model organism for studying peroxisomal biogenesis and methanol assimilation. P. pastoris strains capable of human-type N-glycosylation are now available, which increases the utility of this organism for biopharmaceutical production. Despite its biotechnological importance, relatively few genetic tools or engineered strains have been generated for P. pastoris. To facilitate progress in these areas, we present the 9.43 Mbp genomic sequence of the GS115 strain of P. pastoris. We also provide manually curated annotation for its 5,313 protein-coding genes.

Topik & Kata Kunci

Medicine Biology

Penulis (9)

K. Schutter

Yao-cheng Lin

P. Tiels

A. V. Hecke

Sascha Glinka

J. Weber-Lehmann

P. Rouzé

Y. Peer

N. Callewaert

Format Sitasi

APA MLA BibTeX

Schutter, K., Lin, Y., Tiels, P., Hecke, A.V., Glinka, S., Weber-Lehmann, J. et al. (2009). Genome sequence of the recombinant protein production host Pichia pastoris. https://doi.org/10.1038/nbt.1544

Akses Cepat

Lihat di Sumber doi.org/10.1038/nbt.1544

Informasi Jurnal

Tahun Terbit: 2009
Bahasa: en
Total Sitasi: 505×
Sumber Database: Semantic Scholar
DOI: 10.1038/nbt.1544
Akses: Open Access ✓