Semantic Scholar Open Access 2019 5413 sitasi

Improved metagenomic analysis with Kraken 2

Derrick E. Wood Jennifer Lu Ben Langmead

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Abstrak

Although Kraken’s k-mer-based approach provides a fast taxonomic classification of metagenomic sequence data, its large memory requirements can be limiting for some applications. Kraken 2 improves upon Kraken 1 by reducing memory usage by 85%, allowing greater amounts of reference genomic data to be used, while maintaining high accuracy and increasing speed fivefold. Kraken 2 also introduces a translated search mode, providing increased sensitivity in viral metagenomics analysis.

Topik & Kata Kunci

Medicine Biology Computer Science

Penulis (3)

Derrick E. Wood

Jennifer Lu

Ben Langmead

Format Sitasi

APA MLA BibTeX

Wood, D.E., Lu, J., Langmead, B. (2019). Improved metagenomic analysis with Kraken 2. https://doi.org/10.1186/s13059-019-1891-0

Akses Cepat

Lihat di Sumber doi.org/10.1186/s13059-019-1891-0

Informasi Jurnal

Tahun Terbit: 2019
Bahasa: en
Total Sitasi: 5413×
Sumber Database: Semantic Scholar
DOI: 10.1186/s13059-019-1891-0
Akses: Open Access ✓