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Semantic Scholar Open Access 2004 921 sitasi

The Brain-Derived Neurotrophic Factor val66met Polymorphism and Variation in Human Cortical Morphology

L. Pezawas B. Verchinski V. Mattay J. Callicott B. Kolachana +4 lainnya
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Abstrak

A variation in the BDNF gene (val66met) affects the function of BDNF in neurons, predicts variation in human memory, and is associated with several neurological and psychiatric disorders. Here, we show that, in magnetic resonance imaging scans of a large sample of normal individuals, this polymorphism affects the anatomy of the hippocampus and prefrontal cortex, identifying a genetic mechanism of variation in brain morphology related to learning and memory.

Topik & Kata Kunci

Medicine Psychology

Penulis (9)

L

L. Pezawas

B

B. Verchinski

V

V. Mattay

J

J. Callicott

B

B. Kolachana

R

R. Straub

M

M. Egan

A

A. Meyer-Lindenberg

D

D. Weinberger

Format Sitasi

APA MLA BibTeX
Pezawas, L., Verchinski, B., Mattay, V., Callicott, J., Kolachana, B., Straub, R. et al. (2004). The Brain-Derived Neurotrophic Factor val66met Polymorphism and Variation in Human Cortical Morphology. https://doi.org/10.1523/JNEUROSCI.2680-04.2004

Akses Cepat

Lihat di Sumber doi.org/10.1523/JNEUROSCI.2680-04.2004
Informasi Jurnal
Tahun Terbit
2004
Bahasa
en
Total Sitasi
921×
Sumber Database
Semantic Scholar
DOI
10.1523/JNEUROSCI.2680-04.2004
Akses
Open Access ✓