DOAJ Open Access 2022

Can prevent type 1 diabetes?

Gustavo Frechtel

Abstrak

Type 1 diabetes (T1D) is caused by the autoimmune destruction of β cells of the pancreas, driven by CD4+ and CD8+ T lymphocytes. The humoral branch represented by B lymphocytes is responsible for producing autoantibodies (AAs) against specific antigens such as glutamate decarboxylase (GADA), cellular membrane phosphatase (IA2A/ICA512A), zincT8 transporter (ZincT8A), and the insulin molecule (IAA), all markers of the autoimmune process. These AAs can be detected before the clinical onset of T1D, at the prediabetes type 1 stage (1). The overall risk of progression to T1D is regarded as the presence of 2 or more AAs but differs across patients, being higher with a greater number of AAs (2).

Topik & Kata Kunci

Nutritional diseases. Deficiency diseases Diseases of the endocrine glands. Clinical endocrinology

Penulis (1)

Gustavo Frechtel

Format Sitasi

APA MLA BibTeX

Frechtel, G. (2022). Can prevent type 1 diabetes?. https://doi.org/10.47196/diab.v56i3Sup.590

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Informasi Jurnal

Tahun Terbit: 2022
Sumber Database: DOAJ
DOI: 10.47196/diab.v56i3Sup.590
Akses: Open Access ✓