DOAJ Open Access 2023

Atypical Presentation of Acetylcholinesterase Inhibitor-Induced Diarrhea in Older Adults with Cognitive Decline: An Aspect not to be Underestimated

Raffaele Pagliuca Mario Virgilio Papa Pagliuca Mena Ilaria Virginia Federica Papa Gina Varricchio

Abstrak

The rivastigmine patch is the only existing transdermal delivery system used for the treatment of Alzheimer disease. Among the most common adverse events derived from its use are gastrointestinal events, particularly diarrhea. We report a clinical case of an 81-year-old patient admitted to our hospital under long-standing treatment with rivastigmine transdermal patch who presented with atypical watery diarrhea. Anamnesis showed that the patient presented with a likely infectious gastroenteric event, the diarrheal symptoms of which persisted upon resolution of the event and resolved only upon temporary discontinuation of acetylcholinesterase inhibitors. Failure to rapidly identify the causes of profuse diarrhea in older adults can have lethal consequences. When these symptoms occur, quickly recognizing the causes and providing proper management can be lifesaving.

Topik & Kata Kunci

Penulis (5)

R

Raffaele Pagliuca

M

Mario Virgilio Papa

P

Pagliuca Mena Ilaria

V

Virginia Federica Papa

G

Gina Varricchio

Format Sitasi

Pagliuca, R., Papa, M.V., Ilaria, P.M., Papa, V.F., Varricchio, G. (2023). Atypical Presentation of Acetylcholinesterase Inhibitor-Induced Diarrhea in Older Adults with Cognitive Decline: An Aspect not to be Underestimated. https://doi.org/10.4235/agmr.22.0116

Akses Cepat

Lihat di Sumber doi.org/10.4235/agmr.22.0116
Informasi Jurnal
Tahun Terbit
2023
Sumber Database
DOAJ
DOI
10.4235/agmr.22.0116
Akses
Open Access ✓