DOAJ Open Access 2018

Acute generalised exanthematous pustulosis: An update

Abhishek De Sudip Das Aarti Sarda Dayamay Pal Projna Biswas

Abstrak

Acute generalised exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction and is attributed to drugs in more than 90% of cases. It is a rare disease, with an estimated incidence of 1–5 patients per million per year. The clinical manifestations characterised by the rapid development of sterile pustular lesions, fever and leucocytosis. Number of drugs has been reported to be associated with AGEP, most common being the antibiotics. Histopathologically there is intraepidermal pustules and papillary dermal oedema with neutrophilic and eosinophilic infiltrations. Systemic involvement can be present in more severe cases. Early diagnosis with withdrawal of the causative drug is the most important step in the management. Treatment includes supportive care, prevention of antibiotics and use of a potent topical steroid.

Topik & Kata Kunci

Dermatology

Penulis (5)

Abhishek De

Sudip Das

Aarti Sarda

Dayamay Pal

Projna Biswas

Format Sitasi

APA MLA BibTeX

De, A., Das, S., Sarda, A., Pal, D., Biswas, P. (2018). Acute generalised exanthematous pustulosis: An update. https://doi.org/10.4103/ijd.IJD_581_17

Akses Cepat

PDF tidak tersedia langsung

Cek di sumber asli →

Lihat di Sumber doi.org/10.4103/ijd.IJD_581_17

Informasi Jurnal

Tahun Terbit: 2018
Sumber Database: DOAJ
DOI: 10.4103/ijd.IJD_581_17
Akses: Open Access ✓