Non-Invasive Drug Delivery across the Blood–Brain Barrier: A Prospective Analysis
Abstrak
Non-invasive drug delivery across the blood–brain barrier (BBB) represents a significant advancement in treating neurological diseases. The BBB is a tightly packed layer of endothelial cells that shields the brain from harmful substances in the blood, allowing necessary nutrients to pass through. It is a highly selective barrier, which poses a challenge to delivering therapeutic agents into the brain. Several non-invasive procedures and devices have been developed or are currently being investigated to enhance drug delivery across the BBB. This paper presents a review and a prospective analysis of the art and science that address pharmacology, technology, delivery systems, regulatory approval, ethical concerns, and future possibilities.
Topik & Kata Kunci
Penulis (1)
Sarfaraz K. Niazi
Akses Cepat
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- 2023
- Sumber Database
- DOAJ
- DOI
- 10.3390/pharmaceutics15112599
- Akses
- Open Access ✓