The Multifaceted Role of Curcumin in Advanced Nanocurcumin Form in the Treatment and Management of Chronic Disorders
Abstrak
Curcumin is the primary polyphenol in turmeric’s curcuminoid class. It has a wide range of therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic, hepatoprotective, antibacterial, and anticancer effects against various cancers, but has poor solubility and low bioavailability. Objective: To improve curcumin’s bioavailability, plasma concentration, and cellular permeability processes. The nanocurcumin approach over curcumin has been proven appropriate for encapsulating or loading curcumin (nanocurcumin) to increase its therapeutic potential. Conclusion: Though incorporating curcumin into nanocurcumin form may be a viable method for overcoming its intrinsic limitations, and there are reasonable concerns regarding its toxicological safety once it enters biological pathways. This review article mainly highlights the therapeutic benefits of nanocurcumin over curcumin.
Topik & Kata Kunci
Penulis (15)
Priti Tagde
Pooja Tagde
Fahadul Islam
Sandeep Tagde
Muddaser Shah
Zareen Delawar Hussain
Md. Habibur Rahman
Agnieszka Najda
Ibtesam S. Alanazi
Mousa O. Germoush
Hanan R. H. Mohamed
Mardi M. Algandaby
Mohammed Z. Nasrullah
Natalia Kot
Mohamed M. Abdel-Daim
Akses Cepat
- Tahun Terbit
- 2021
- Sumber Database
- DOAJ
- DOI
- 10.3390/molecules26237109
- Akses
- Open Access ✓