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DOAJ Open Access 2020

A Survey of Synthetic Routes and Antitumor Activities for Benzo[<i>g</i>]quinoxaline-5,10-diones

Alain G. Giuglio-Tonolo Christophe Curti Thierry Terme Patrice Vanelle
Lihat Sumber DOI

Abstrak

Anthracycline antibiotics play an important role in cancer chemotherapy. The need to improve their therapeutic index has stimulated an ongoing search for anthracycline analogs with enhanced properties. This review aims to summarize the common synthetic approaches to benzo[<i>g</i>]quinoxaline-5,10-diones and their uses in heterocyclic chemistry. Because of the valuable biological activities of the 1,4-diazaanthraquinone compounds, a summary of the most promising heterocyclic quinones is provided together with their antitumor properties.

Topik & Kata Kunci

Organic chemistry

Penulis (4)

A

Alain G. Giuglio-Tonolo

C

Christophe Curti

T

Thierry Terme

P

Patrice Vanelle

Format Sitasi

APA MLA BibTeX
Giuglio-Tonolo, A.G., Curti, C., Terme, T., Vanelle, P. (2020). A Survey of Synthetic Routes and Antitumor Activities for Benzo[<i>g</i>]quinoxaline-5,10-diones. https://doi.org/10.3390/molecules25245922

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Informasi Jurnal
Tahun Terbit
2020
Sumber Database
DOAJ
DOI
10.3390/molecules25245922
Akses
Open Access ✓