DOAJ Open Access 2018

Morphological, Release and Antibacterial Performances of Amoxicillin-Loaded Cellulose Aerogels

Shan Ye Shu He Chen Su Lei Jiang Yanyi Wen +2 lainnya

Lihat Sumber DOI

Abstrak

Cellulose has been widely used in the biomedical field. In this study, novel cellulose aerogels were firstly prepared in a NaOH-based solvent system by a facile casting method. Then amoxicillin was successfully loaded into cellulose aerogels with different loadings. The morphology and structure of the cellulose aerogels were characterized using scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). The drug release and antibacterial activities were also evaluated. The drug release results showed that cellulose aerogels have controlled amoxicillin release performance. In vitro antibacterial assay demonstrated that the cellulose aerogels exhibited excellent antibacterial activity with the amoxicillin dose-dependent activity. Therefore, the developed cellulose aerogels display controlled release behavior and efficient antibacterial performance, thus confirming their potential for biomedical applications.

Topik & Kata Kunci

Organic chemistry

Penulis (7)

Shan Ye

Shu He

Chen Su

Lei Jiang

Yanyi Wen

Zhongjie Zhu

Wei Shao

Format Sitasi

APA MLA BibTeX

Ye, S., He, S., Su, C., Jiang, L., Wen, Y., Zhu, Z. et al. (2018). Morphological, Release and Antibacterial Performances of Amoxicillin-Loaded Cellulose Aerogels. https://doi.org/10.3390/molecules23082082

Akses Cepat

Lihat di Sumber doi.org/10.3390/molecules23082082

Informasi Jurnal

Tahun Terbit: 2018
Sumber Database: DOAJ
DOI: 10.3390/molecules23082082
Akses: Open Access ✓