DOAJ Open Access 2016

New 30-Noroleanane Triterpenoid Saponins from Holboellia coriacea Diels

Wenbing Ding Ye Li Guanhua Li Hualiang He Zhiwen Li +1 lainnya

Lihat Sumber DOI

Abstrak

Three new 30-noroleanane triterpenoid saponins, akebonoic acid 28-O-β-d-glucopyranosyl-(1′′→6′)-β-d-glucopyranosyl ester (1), akebonoic acid 28-O-(6′′-O-caffeoyl)-β-d-glucopyranosyl-(1′′→6′)-β-d-glucopyranosyl ester (Holboelliside A, 2) and 3β,20α,24-trihydroxy-29-norolean-12-en-28-oic acid 3-O-(6′-O-caffeoyl)-β-d-glucopyranoside (Holboelliside B, 3) were isolated from the stems of Holboellia coriacea Diels, together with five known compounds, eupteleasaponin VIII (4), 3α-akebonoic acid (5), quinatic acid (6), 3β-hydroxy-30-norhederagenin (7) and quinatoside A (8). The structures of these compounds were determined on the basis of spectral and chemical evidence. Compounds 1–5 were evaluated for their inhibitory activity against three human tumors HepG2, HCT116 and SGC-7901 cell lines in vitro.

Topik & Kata Kunci

Organic chemistry

Penulis (6)

Wenbing Ding

Ye Li

Guanhua Li

Hualiang He

Zhiwen Li

Youzhi Li

Format Sitasi

APA MLA BibTeX

Ding, W., Li, Y., Li, G., He, H., Li, Z., Li, Y. (2016). New 30-Noroleanane Triterpenoid Saponins from Holboellia coriacea Diels. https://doi.org/10.3390/molecules21060734

Akses Cepat

Lihat di Sumber doi.org/10.3390/molecules21060734

Informasi Jurnal

Tahun Terbit: 2016
Sumber Database: DOAJ
DOI: 10.3390/molecules21060734
Akses: Open Access ✓