DOAJ Open Access 2014

Cyclodepsipeptides and Other O-Containing Heterocyclic Metabolites from Beauveria felina EN-135, a Marine-Derived Entomopathogenic Fungus

Feng-Yu Du Xiao-Ming Li Peng Zhang Chun-Shun Li Bin-Gui Wang

Abstrak

Bioassay-guided fractionation of a culture extract of Beauveria felina EN-135, an entomopathogenic fungus isolated from a marine bryozoan, led to the isolation of a new cyclodepsipeptide, iso-isariin D (1); two new O-containing heterocyclic compounds that we have named felinones A and B (2 and 3); and four known cyclodepsipeptides (4–7). The structures were elucidated via spectroscopic analysis, and the absolute configurations of 1 and 2 were determined using single-crystal X-ray diffraction and CD, respectively. All isolated compounds were evaluated for antimicrobial activity and brine-shrimp (Artemia salina) lethality.

Topik & Kata Kunci

Penulis (5)

F

Feng-Yu Du

X

Xiao-Ming Li

P

Peng Zhang

C

Chun-Shun Li

B

Bin-Gui Wang

Format Sitasi

Du, F., Li, X., Zhang, P., Li, C., Wang, B. (2014). Cyclodepsipeptides and Other O-Containing Heterocyclic Metabolites from Beauveria felina EN-135, a Marine-Derived Entomopathogenic Fungus. https://doi.org/10.3390/md12052816

Akses Cepat

Lihat di Sumber doi.org/10.3390/md12052816
Informasi Jurnal
Tahun Terbit
2014
Sumber Database
DOAJ
DOI
10.3390/md12052816
Akses
Open Access ✓